Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRPE |
Texto Completo: | http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8815 |
Resumo: | The aim of this study was to determine the prevalence of Toxoplasma gondii (T. gondii) and Leptospira spp. in humans and identify risk factors associated with T. gondii infection in the Fernando de Noronha archipelago, Pernambuco, Brazil. For detection of anti-Toxoplasma gondii and anti-Leptospira antibodies, indirect fluorescent antibody test (IFAT) and Microscopic agglutination test (MAT), were used respectively. The risk factors were identified through the application of an epidemiological questionnaire and variables were analyzed by univariate analysis and logistic regression. The seroprevalence of immunoglobulin G anti-T. gondii antibodies was 50.4%. Factors associated with infection: consumption of well water or rainwater (odds ratio [OR]: 2.43, p=0.020) and consumption of game meat (OR: 1.80, p=0.026). The prevalence of anti-Leptospira antibodies was 1.17% (4/341), and the serovars identified were: Icterohaemorrhagiae, Javanica, Mini and Louisiana. This is the first study that addresses these infections in humans in the Fernando de Noronha Archipelago. The results of this study indicate the urgent need for intervention by local, health authorities with integrated and strategic measures in the prevention and control of these diseases. In addition, it is important aware the residents of the Island of Fernando de Noronha about of the transmission routes of Toxoplasma gondii and Leptospira spp. |
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MOTA, Rinaldo AparecidoPINHEIRO JUNIOR, José WiltonMELO, Renata Pimentel Bandeira deANDRADE, Müller RibeiroFERREIRA, Débora Rochelly Alveshttp://lattes.cnpq.br/6878921371244273CARVALHO, Maria da Conceição2023-02-03T22:13:40Z2020-02-20CARVALHO, Maria da Conceição. Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil. 2020. 124 f. Tese (Programa de Pós-Graduação em Ciência Animal Tropical) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8815The aim of this study was to determine the prevalence of Toxoplasma gondii (T. gondii) and Leptospira spp. in humans and identify risk factors associated with T. gondii infection in the Fernando de Noronha archipelago, Pernambuco, Brazil. For detection of anti-Toxoplasma gondii and anti-Leptospira antibodies, indirect fluorescent antibody test (IFAT) and Microscopic agglutination test (MAT), were used respectively. The risk factors were identified through the application of an epidemiological questionnaire and variables were analyzed by univariate analysis and logistic regression. The seroprevalence of immunoglobulin G anti-T. gondii antibodies was 50.4%. Factors associated with infection: consumption of well water or rainwater (odds ratio [OR]: 2.43, p=0.020) and consumption of game meat (OR: 1.80, p=0.026). The prevalence of anti-Leptospira antibodies was 1.17% (4/341), and the serovars identified were: Icterohaemorrhagiae, Javanica, Mini and Louisiana. This is the first study that addresses these infections in humans in the Fernando de Noronha Archipelago. The results of this study indicate the urgent need for intervention by local, health authorities with integrated and strategic measures in the prevention and control of these diseases. In addition, it is important aware the residents of the Island of Fernando de Noronha about of the transmission routes of Toxoplasma gondii and Leptospira spp.Objetivou-se determinar a prevalência da infecção por Toxoplasma gondii (T. gondii) e Leptospira spp. em humanos e identificar os fatores de risco associados à infecção por T. gondii no Arquipélago de Fernando de Noronha, Pernambuco, Brasil. Para detecção de anticorpos IgG anti-Toxoplasma gondii e anti-Leptospira empregaram-se a Reações de Imunofluorescência Indireta (RIFI) e Soroaglutinação Microscópica (SAM), respectivamente. Os fatores de risco foram identificados por meio da aplicação de um questionário epidemiológico e as variáveis foram analisadas por meio da análise univariada e regressão logística. A soroprevalência de anticorpos IgG anti-T. gondi foi de 50,4% (172/341) e foram identificados dois fatores de risco associados à infecção: consumo de água de poço/chuva (OR: 2,43; p= 0,020) e consumo de animais silvestres (OR: 1,80; p = 0,026). A prevalência de anticorpos anti-Leptospira foi de 1,17% (4/341) e os sorovares identificados foram: Icterohaemorrhagiae, Javanica, Mini e Louisiana. Esse é o primeiro estudo que aborda estas infecções em humanos no Arquipélago de Fernando de Noronha. Os resultados alertam para a necessidade de intervenção por parte das autoridades de saúde local, com medidas estratégicas e integradas na prevenção e controle dessas enfermidades. Além disso, é importante conscientizar os habitantes da ilha de Fernando de Noronha sobre as vias de tranmissão de Toxoplasma gondii e Leptospira spp.Submitted by (lucia.rodrigues@ufrpe.br) on 2023-02-03T22:13:40Z No. of bitstreams: 1 Maria da Conceicao Carvalho.pdf: 1929354 bytes, checksum: fa261eadb19cffe749e493b58684f820 (MD5)Made available in DSpace on 2023-02-03T22:13:40Z (GMT). No. of bitstreams: 1 Maria da Conceicao Carvalho.pdf: 1929354 bytes, checksum: fa261eadb19cffe749e493b58684f820 (MD5) Previous issue date: 2020-02-20application/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em Ciência Animal TropicalUFRPEBrasilDepartamento de Morfologia e Fisiologia AnimalToxoplasma gondiiLeptospira spp.SoroprevalênciaEpidemiologiaFernando de Noronha (PE)CIENCIAS AGRARIAS::MEDICINA VETERINARIASoroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis-6143187600765506511600600600-8922364187987396204453670264235017319info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRPEinstname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEORIGINALMaria da Conceicao Carvalho.pdfMaria da Conceicao Carvalho.pdfapplication/pdf1929354http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8815/2/Maria+da+Conceicao+Carvalho.pdffa261eadb19cffe749e493b58684f820MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8815/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede2/88152023-02-03 19:13:40.976oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.tede2.ufrpe.br:8080/tede/PUBhttp://www.tede2.ufrpe.br:8080/oai/requestbdtd@ufrpe.br ||bdtd@ufrpe.bropendoar:2024-05-28T12:37:27.999Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE)false |
dc.title.por.fl_str_mv |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
title |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
spellingShingle |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil CARVALHO, Maria da Conceição Toxoplasma gondii Leptospira spp. Soroprevalência Epidemiologia Fernando de Noronha (PE) CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
title_full |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
title_fullStr |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
title_full_unstemmed |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
title_sort |
Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil |
author |
CARVALHO, Maria da Conceição |
author_facet |
CARVALHO, Maria da Conceição |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
MOTA, Rinaldo Aparecido |
dc.contributor.referee1.fl_str_mv |
PINHEIRO JUNIOR, José Wilton |
dc.contributor.referee2.fl_str_mv |
MELO, Renata Pimentel Bandeira de |
dc.contributor.referee3.fl_str_mv |
ANDRADE, Müller Ribeiro |
dc.contributor.referee4.fl_str_mv |
FERREIRA, Débora Rochelly Alves |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/6878921371244273 |
dc.contributor.author.fl_str_mv |
CARVALHO, Maria da Conceição |
contributor_str_mv |
MOTA, Rinaldo Aparecido PINHEIRO JUNIOR, José Wilton MELO, Renata Pimentel Bandeira de ANDRADE, Müller Ribeiro FERREIRA, Débora Rochelly Alves |
dc.subject.por.fl_str_mv |
Toxoplasma gondii Leptospira spp. Soroprevalência Epidemiologia Fernando de Noronha (PE) |
topic |
Toxoplasma gondii Leptospira spp. Soroprevalência Epidemiologia Fernando de Noronha (PE) CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.cnpq.fl_str_mv |
CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
The aim of this study was to determine the prevalence of Toxoplasma gondii (T. gondii) and Leptospira spp. in humans and identify risk factors associated with T. gondii infection in the Fernando de Noronha archipelago, Pernambuco, Brazil. For detection of anti-Toxoplasma gondii and anti-Leptospira antibodies, indirect fluorescent antibody test (IFAT) and Microscopic agglutination test (MAT), were used respectively. The risk factors were identified through the application of an epidemiological questionnaire and variables were analyzed by univariate analysis and logistic regression. The seroprevalence of immunoglobulin G anti-T. gondii antibodies was 50.4%. Factors associated with infection: consumption of well water or rainwater (odds ratio [OR]: 2.43, p=0.020) and consumption of game meat (OR: 1.80, p=0.026). The prevalence of anti-Leptospira antibodies was 1.17% (4/341), and the serovars identified were: Icterohaemorrhagiae, Javanica, Mini and Louisiana. This is the first study that addresses these infections in humans in the Fernando de Noronha Archipelago. The results of this study indicate the urgent need for intervention by local, health authorities with integrated and strategic measures in the prevention and control of these diseases. In addition, it is important aware the residents of the Island of Fernando de Noronha about of the transmission routes of Toxoplasma gondii and Leptospira spp. |
publishDate |
2020 |
dc.date.issued.fl_str_mv |
2020-02-20 |
dc.date.accessioned.fl_str_mv |
2023-02-03T22:13:40Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
format |
doctoralThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
CARVALHO, Maria da Conceição. Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil. 2020. 124 f. Tese (Programa de Pós-Graduação em Ciência Animal Tropical) - Universidade Federal Rural de Pernambuco, Recife. |
dc.identifier.uri.fl_str_mv |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8815 |
identifier_str_mv |
CARVALHO, Maria da Conceição. Soroepidemiologia da infecção por Toxoplasma gondii e Leptospira spp. em humanos no Arquipélago de Fernando de Noronha, Pernambuco, Brasil. 2020. 124 f. Tese (Programa de Pós-Graduação em Ciência Animal Tropical) - Universidade Federal Rural de Pernambuco, Recife. |
url |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8815 |
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por |
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por |
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600 600 600 |
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453670264235017319 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Universidade Federal Rural de Pernambuco |
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Programa de Pós-Graduação em Ciência Animal Tropical |
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UFRPE |
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Brasil |
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Departamento de Morfologia e Fisiologia Animal |
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Universidade Federal Rural de Pernambuco |
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