Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades

Detalhes bibliográficos
Autor(a) principal: ANDRADE NETO, Adony Querubino de
Data de Publicação: 2021
Tipo de documento: Tese
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFRPE
Texto Completo: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8864
Resumo: There are still many questions about the etiopathogenesis of abomasum ulcers that affect cattle and that impact on animal production, causing significant economic losses. In the last ten years, there has been greater interest from the scientific community in clarifying the possible cause and effect relationships of this disease. Therefore, the aim of this study was to conduct an epidemiological and anatomopathological study in cattle with abomasal ulcers and carriers the comorbidities. A total of 201 cattle were used, 40/201 (20%) young animals under the age of two years and 161/201 (80%) adults, aged over two and a half years, and diagnosed with type 1 or 2 ulcers in the pathological examination and 25 cattle, young (n=8, less than two years old) and adults (n=17, older than two and a half years), diagnosed with perforated abomasal ulcers of the type 3, 4 or 5, in clinical, ultrasonographic, exploratory laparotomy, abdominal centesis or pathological examination. Epidemiological risk indicators such as; sex, race, age, type of rearing, feeding, time of year, health practices and stage of lactation, as well as clinical, pathological diagnostic data were collected through medical records. At necropsy, the ulcers were analyzed for the degree of penetration into the mucosa, bleeding and topographic distribution by affected region, cardia, fundus and pylorus, as well as the abdominal cavity was evaluated for the presence of peritonitis. For histopathological examination, the ulcers were fixed in 10% buffered formalin, processed by routine protocol and stained with hematoxylin-eosin (HE). There was a higher occurrence of cases of abomasum ulcers in females, in the dry period (October to March). In the macroscopic examination of the abomasum, focal ulcers subtype 1b and multifocal ulcers subtype 1a and 1b were the most common, respectively. Ulcers abomasum type 1 and 2 were characterized by focal inflammatory process, focally extensive multifocal or diffuse, particularly by mononuclear cells. Abomasitis associated with ulcerated mucosa was found in 160/201 (79.60%), with lymphoid follicle hyperplasia in 104/201 (51.74%). On 26/201 (12.93%), abomasitis had diffuse foci of multifocal lymphocytic proliferation by atypical lymphocytes. In the histopathology of perforated ulcers, lymphocytic and neutrophilic abomasitis was found in most cases, associated with fibrosis with thrombosis of vessels. The main clinical findings in animals with perforated ulcer were: apathy, dehydration, intestinal hypomotility, diarrheal stools, hypomotile or atonic rumen, tachycardia, tachypnea, abdominal distension with bilateral bulging and increased abdominal tension. The most frequent abnormal hematological findings were hypoproteinemia and leukocytosis due to neutrophilia with a left shift. Peritoneal fluid (LP) from animals with perforated ulcers showed an inflammatory reaction in cytology, characteristic of exudate. The diagnosis of perforated ulcer was possible in three cases on ultrasound and in two cases on exploratory laparotomy. In the postmortem examination, all cases of type 3, 4 or 5 ulcers presented focal peritonitis, diffuse peritonitis or omental bursitis, respectively. Comorbidities were present in 68% and 100% of cases in animals with perforated ulcers and type 1 and 2, respectively, the most frequent being related to the digestive system. Thus, the results of this study emphasize the occurrence of type 1 abomasal ulcers in dairy cattle carriers the primary comorbidities. Although type 1 ulcers do not cause characteristic clinical signs, it is possible that they are an important cause of abdominal pain and decreased production in dairy cattle, on the other hand, perforated ulcers cause clinical signs suggestive of pertitonitis, and thus ultrasonography with abdominal centesis and exploratory laparotomy are necessary tools to predict them, and a diagnosis is always possible when these tests are combined, helping the veterinarian in making decisions to avoid further animal suffering and unnecessary treatment costs. Once, the cases of type 4 or 5 ulcers present unfavorable clinical evolution.
id URPE_7396c5d0895da945ab74944a1d49bc29
oai_identifier_str oai:tede2:tede2/8864
network_acronym_str URPE
network_name_str Biblioteca Digital de Teses e Dissertações da UFRPE
repository_id_str
spelling SILVA, José Augusto Bastos Afonso daMENDONÇA, Carla Lopes deBORGES, José Renato JunqueiraSÁ, Lilian Rose Marques deSUCUPIRA, Maria Claudia Araripehttp://lattes.cnpq.br/5290238321402289ANDRADE NETO, Adony Querubino de2023-03-09T22:49:04Z2021-02-23ANDRADE NETO, Adony Querubino de. Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades. 2021. 141 f. Tese (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8864There are still many questions about the etiopathogenesis of abomasum ulcers that affect cattle and that impact on animal production, causing significant economic losses. In the last ten years, there has been greater interest from the scientific community in clarifying the possible cause and effect relationships of this disease. Therefore, the aim of this study was to conduct an epidemiological and anatomopathological study in cattle with abomasal ulcers and carriers the comorbidities. A total of 201 cattle were used, 40/201 (20%) young animals under the age of two years and 161/201 (80%) adults, aged over two and a half years, and diagnosed with type 1 or 2 ulcers in the pathological examination and 25 cattle, young (n=8, less than two years old) and adults (n=17, older than two and a half years), diagnosed with perforated abomasal ulcers of the type 3, 4 or 5, in clinical, ultrasonographic, exploratory laparotomy, abdominal centesis or pathological examination. Epidemiological risk indicators such as; sex, race, age, type of rearing, feeding, time of year, health practices and stage of lactation, as well as clinical, pathological diagnostic data were collected through medical records. At necropsy, the ulcers were analyzed for the degree of penetration into the mucosa, bleeding and topographic distribution by affected region, cardia, fundus and pylorus, as well as the abdominal cavity was evaluated for the presence of peritonitis. For histopathological examination, the ulcers were fixed in 10% buffered formalin, processed by routine protocol and stained with hematoxylin-eosin (HE). There was a higher occurrence of cases of abomasum ulcers in females, in the dry period (October to March). In the macroscopic examination of the abomasum, focal ulcers subtype 1b and multifocal ulcers subtype 1a and 1b were the most common, respectively. Ulcers abomasum type 1 and 2 were characterized by focal inflammatory process, focally extensive multifocal or diffuse, particularly by mononuclear cells. Abomasitis associated with ulcerated mucosa was found in 160/201 (79.60%), with lymphoid follicle hyperplasia in 104/201 (51.74%). On 26/201 (12.93%), abomasitis had diffuse foci of multifocal lymphocytic proliferation by atypical lymphocytes. In the histopathology of perforated ulcers, lymphocytic and neutrophilic abomasitis was found in most cases, associated with fibrosis with thrombosis of vessels. The main clinical findings in animals with perforated ulcer were: apathy, dehydration, intestinal hypomotility, diarrheal stools, hypomotile or atonic rumen, tachycardia, tachypnea, abdominal distension with bilateral bulging and increased abdominal tension. The most frequent abnormal hematological findings were hypoproteinemia and leukocytosis due to neutrophilia with a left shift. Peritoneal fluid (LP) from animals with perforated ulcers showed an inflammatory reaction in cytology, characteristic of exudate. The diagnosis of perforated ulcer was possible in three cases on ultrasound and in two cases on exploratory laparotomy. In the postmortem examination, all cases of type 3, 4 or 5 ulcers presented focal peritonitis, diffuse peritonitis or omental bursitis, respectively. Comorbidities were present in 68% and 100% of cases in animals with perforated ulcers and type 1 and 2, respectively, the most frequent being related to the digestive system. Thus, the results of this study emphasize the occurrence of type 1 abomasal ulcers in dairy cattle carriers the primary comorbidities. Although type 1 ulcers do not cause characteristic clinical signs, it is possible that they are an important cause of abdominal pain and decreased production in dairy cattle, on the other hand, perforated ulcers cause clinical signs suggestive of pertitonitis, and thus ultrasonography with abdominal centesis and exploratory laparotomy are necessary tools to predict them, and a diagnosis is always possible when these tests are combined, helping the veterinarian in making decisions to avoid further animal suffering and unnecessary treatment costs. Once, the cases of type 4 or 5 ulcers present unfavorable clinical evolution.Muitos são ainda os questionamentos quanto a etiopatogenia das úlceras do abomaso que acometem os bovinos e que impactam na produção animal, causando prejuízos econômicos expressivos. Nos últimos dez anos, houve um maior interesse da comunidade científica em esclarecer as possíveis relações de causa e efeitos desta enfermidade. Diante disso, o objetivo deste trabalho foi realizar um estudo, epidemiológico e anatomopatológico em bovinos com úlceras do abomaso e portadores de comorbidades. Foram utilizados 201 bovinos, 40/201 (20%) jovens com idade inferior a dois anos e 161/201 (80%) adultos, com idade superior a dois anos e meio, e diagnosticados com úlceras tipo 1 ou 2 no exame anatomopatologico e 25 bovinos, jovens (n=8, idade inferior a dois anos) e adultos (n=17, idade superior a dois anos e meio), diagnosticados com úlceras do abomaso perfuradas do tipo 3, 4 ou 5, no exame clínico, ultrassonografico, de laparotomia exploratória, centese abdominal ou anatomopatológico. Os indicadores epidemiológicos de risco como; sexo, raça, idade, tipo de criação, alimentação, época do ano, práticas sanitárias e estágio de lactação, assim como os dados clínicos, anatomopatológico e de diagnóstico foram coletados por meio dos prontuários clínicos. Na necropsia as úlceras foram analisadas quanto ao grau de penetração na mucosa, sangramento e distribuição topográfica por região acometida, cárdica, fúndica e pilórica bem como a cavidade abdominal foi avaliada quanto a presença de peritonite. Para o exame histopatológico, as úlceras foram fixadas em formalina tamponada a 10%, processadas por protocolo de rotina e coradas com hematoxilina-eosina (HE). Houve uma maior ocorrência dos casos de úlceras do abomaso em fêmeas, no período seco (outubro a março). No exame macroscópico do abomaso, úlceras focais subtipo 1b e úlceras múltifocais subtipo 1a e 1b foram as mais encontradas, respectivamente. As úlceras do abomaso tipo 1 e 2 foram caracterizadas por processo inflamatório focal, focalmente extenso, multifocais ou difusos, principalmente por células mononucleares. Abomasite associada a mucosa ulcerada foi encontrada em 160/201 (79,60%), com hiperplasia de folículos linfoides em 104/201 (51,74%). Em 26/201 (12,93%) a abomasite apresentava focos difusos de proliferação linfocítica multifocal por linfócitos atípicos. Na histopatologia das úlceras perfuradas, abomasite linfocítica e neutrofílica foi encontrada na maioria dos casos, associado a fibrose com trombose de vasos. Os principais achados clínicos nos animais com úlcera perfurada foram: apatia, desidratação, hipomotilidade intestinal, fezes diarreicas, rúmen hipomotílico ou atônico, taquicardia, taquipneia, distensão abdominal com abaulamento bilateral e tensão abdominal aumentada. Os achados hematológicos anormais mais frequentes foram hipoproteinemia e leucocitose por neutrofilia com desvio a esquerda. O líquido peritoneal (LP) dos animais com úlcera perfurada, evidenciou reação inflamatória, na citologia, característica de exsudato. O diagnóstico de úlcera perfurada foi possível em três casos na ultrassonografia e em dois casos na laparotomia exploratória. No exame posmortem todos os casos de úlcera tipo 3, 4 ou 5, apresentaram peritonite focal, peritonite difusa ou bursite omental, respectivamente. As comorbidades estavam presentes em 68% e 100% dos casos em animais com ulceras perfuradas e do tipo 1 e 2, respectivamente, sendo as mais frequentes relacionadas ao sistema digestivo. Sendo assim, os resultados deste estudo enfatiza a ocorrência de úlceras do abomaso tipo 1 em bovinos leiteiros com diferentes comorbidades prmárias. Embora, as úlceras tipo 1 não causem sinais clínicos característicos, é possível que sejam causa importante de dor abdominal e da diminuição da produção em bovinos leiteiros, por outro lado, as úlceras perfuradas causam sinais clinicos sugestivos de pertitonite, e dessa forma a ultrassonografia com a centese abdominal e a laparotomia exploratória, constituem ferramentas necessárias para predizê-las, e sempre é possível um diagnóstico quando esses exames são combinados, auxiliando o veterinário na tomada de decisões para evitar mais sofrimento do animal e custos desnecessários com o tratamento. Uma vez que, os casos de úlceras tipo 4 ou 5 apresentam evolução clinica desfavorável.Submitted by (lucia.rodrigues@ufrpe.br) on 2023-03-09T22:49:04Z No. of bitstreams: 1 Adony Querubino de Andrade Neto.pdf: 3019996 bytes, checksum: 01e4c8ee17cb39c32c624534238965bf (MD5)Made available in DSpace on 2023-03-09T22:49:04Z (GMT). No. of bitstreams: 1 Adony Querubino de Andrade Neto.pdf: 3019996 bytes, checksum: 01e4c8ee17cb39c32c624534238965bf (MD5) Previous issue date: 2021-02-23Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em Ciência VeterináriaUFRPEBrasilDepartamento de Medicina VeterináriaAbomasoBovino de leiteDiagnósticoLesão ulcerativaMelenaPeritoniteComorbidadeExame anatomopatológicoCIENCIAS AGRARIAS::MEDICINA VETERINARIAÚlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidadesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis-3061482854177903105600600600600-30202105637636167804536702642350173192075167498588264571info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRPEinstname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEORIGINALAdony Querubino de Andrade Neto.pdfAdony Querubino de Andrade Neto.pdfapplication/pdf3019996http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8864/2/Adony+Querubino+de+Andrade+Neto.pdf01e4c8ee17cb39c32c624534238965bfMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8864/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede2/88642023-03-09 19:49:05.031oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.tede2.ufrpe.br:8080/tede/PUBhttp://www.tede2.ufrpe.br:8080/oai/requestbdtd@ufrpe.br ||bdtd@ufrpe.bropendoar:2024-05-28T12:37:31.807500Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE)false
dc.title.por.fl_str_mv Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
title Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
spellingShingle Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
ANDRADE NETO, Adony Querubino de
Abomaso
Bovino de leite
Diagnóstico
Lesão ulcerativa
Melena
Peritonite
Comorbidade
Exame anatomopatológico
CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
title_full Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
title_fullStr Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
title_full_unstemmed Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
title_sort Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades
author ANDRADE NETO, Adony Querubino de
author_facet ANDRADE NETO, Adony Querubino de
author_role author
dc.contributor.advisor1.fl_str_mv SILVA, José Augusto Bastos Afonso da
dc.contributor.referee1.fl_str_mv MENDONÇA, Carla Lopes de
dc.contributor.referee2.fl_str_mv BORGES, José Renato Junqueira
dc.contributor.referee3.fl_str_mv SÁ, Lilian Rose Marques de
dc.contributor.referee4.fl_str_mv SUCUPIRA, Maria Claudia Araripe
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/5290238321402289
dc.contributor.author.fl_str_mv ANDRADE NETO, Adony Querubino de
contributor_str_mv SILVA, José Augusto Bastos Afonso da
MENDONÇA, Carla Lopes de
BORGES, José Renato Junqueira
SÁ, Lilian Rose Marques de
SUCUPIRA, Maria Claudia Araripe
dc.subject.por.fl_str_mv Abomaso
Bovino de leite
Diagnóstico
Lesão ulcerativa
Melena
Peritonite
Comorbidade
Exame anatomopatológico
topic Abomaso
Bovino de leite
Diagnóstico
Lesão ulcerativa
Melena
Peritonite
Comorbidade
Exame anatomopatológico
CIENCIAS AGRARIAS::MEDICINA VETERINARIA
dc.subject.cnpq.fl_str_mv CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description There are still many questions about the etiopathogenesis of abomasum ulcers that affect cattle and that impact on animal production, causing significant economic losses. In the last ten years, there has been greater interest from the scientific community in clarifying the possible cause and effect relationships of this disease. Therefore, the aim of this study was to conduct an epidemiological and anatomopathological study in cattle with abomasal ulcers and carriers the comorbidities. A total of 201 cattle were used, 40/201 (20%) young animals under the age of two years and 161/201 (80%) adults, aged over two and a half years, and diagnosed with type 1 or 2 ulcers in the pathological examination and 25 cattle, young (n=8, less than two years old) and adults (n=17, older than two and a half years), diagnosed with perforated abomasal ulcers of the type 3, 4 or 5, in clinical, ultrasonographic, exploratory laparotomy, abdominal centesis or pathological examination. Epidemiological risk indicators such as; sex, race, age, type of rearing, feeding, time of year, health practices and stage of lactation, as well as clinical, pathological diagnostic data were collected through medical records. At necropsy, the ulcers were analyzed for the degree of penetration into the mucosa, bleeding and topographic distribution by affected region, cardia, fundus and pylorus, as well as the abdominal cavity was evaluated for the presence of peritonitis. For histopathological examination, the ulcers were fixed in 10% buffered formalin, processed by routine protocol and stained with hematoxylin-eosin (HE). There was a higher occurrence of cases of abomasum ulcers in females, in the dry period (October to March). In the macroscopic examination of the abomasum, focal ulcers subtype 1b and multifocal ulcers subtype 1a and 1b were the most common, respectively. Ulcers abomasum type 1 and 2 were characterized by focal inflammatory process, focally extensive multifocal or diffuse, particularly by mononuclear cells. Abomasitis associated with ulcerated mucosa was found in 160/201 (79.60%), with lymphoid follicle hyperplasia in 104/201 (51.74%). On 26/201 (12.93%), abomasitis had diffuse foci of multifocal lymphocytic proliferation by atypical lymphocytes. In the histopathology of perforated ulcers, lymphocytic and neutrophilic abomasitis was found in most cases, associated with fibrosis with thrombosis of vessels. The main clinical findings in animals with perforated ulcer were: apathy, dehydration, intestinal hypomotility, diarrheal stools, hypomotile or atonic rumen, tachycardia, tachypnea, abdominal distension with bilateral bulging and increased abdominal tension. The most frequent abnormal hematological findings were hypoproteinemia and leukocytosis due to neutrophilia with a left shift. Peritoneal fluid (LP) from animals with perforated ulcers showed an inflammatory reaction in cytology, characteristic of exudate. The diagnosis of perforated ulcer was possible in three cases on ultrasound and in two cases on exploratory laparotomy. In the postmortem examination, all cases of type 3, 4 or 5 ulcers presented focal peritonitis, diffuse peritonitis or omental bursitis, respectively. Comorbidities were present in 68% and 100% of cases in animals with perforated ulcers and type 1 and 2, respectively, the most frequent being related to the digestive system. Thus, the results of this study emphasize the occurrence of type 1 abomasal ulcers in dairy cattle carriers the primary comorbidities. Although type 1 ulcers do not cause characteristic clinical signs, it is possible that they are an important cause of abdominal pain and decreased production in dairy cattle, on the other hand, perforated ulcers cause clinical signs suggestive of pertitonitis, and thus ultrasonography with abdominal centesis and exploratory laparotomy are necessary tools to predict them, and a diagnosis is always possible when these tests are combined, helping the veterinarian in making decisions to avoid further animal suffering and unnecessary treatment costs. Once, the cases of type 4 or 5 ulcers present unfavorable clinical evolution.
publishDate 2021
dc.date.issued.fl_str_mv 2021-02-23
dc.date.accessioned.fl_str_mv 2023-03-09T22:49:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv ANDRADE NETO, Adony Querubino de. Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades. 2021. 141 f. Tese (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.
dc.identifier.uri.fl_str_mv http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8864
identifier_str_mv ANDRADE NETO, Adony Querubino de. Úlceras do abomaso: estudo epidemiológico e anatomopatológico em bovinos com comorbidades. 2021. 141 f. Tese (Programa de Pós-Graduação em Ciência Veterinária) - Universidade Federal Rural de Pernambuco, Recife.
url http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8864
dc.language.iso.fl_str_mv por
language por
dc.relation.program.fl_str_mv -3061482854177903105
dc.relation.confidence.fl_str_mv 600
600
600
600
dc.relation.department.fl_str_mv -3020210563763616780
dc.relation.cnpq.fl_str_mv 453670264235017319
dc.relation.sponsorship.fl_str_mv 2075167498588264571
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal Rural de Pernambuco
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Ciência Veterinária
dc.publisher.initials.fl_str_mv UFRPE
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Departamento de Medicina Veterinária
publisher.none.fl_str_mv Universidade Federal Rural de Pernambuco
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações da UFRPE
instname:Universidade Federal Rural de Pernambuco (UFRPE)
instacron:UFRPE
instname_str Universidade Federal Rural de Pernambuco (UFRPE)
instacron_str UFRPE
institution UFRPE
reponame_str Biblioteca Digital de Teses e Dissertações da UFRPE
collection Biblioteca Digital de Teses e Dissertações da UFRPE
bitstream.url.fl_str_mv http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8864/2/Adony+Querubino+de+Andrade+Neto.pdf
http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/8864/1/license.txt
bitstream.checksum.fl_str_mv 01e4c8ee17cb39c32c624534238965bf
bd3efa91386c1718a7f26a329fdcb468
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE)
repository.mail.fl_str_mv bdtd@ufrpe.br ||bdtd@ufrpe.br
_version_ 1810102268588982272