Avaliação do programa de vigilância da febre amarela silvestre em primatas não humanos no estado de Pernambuco, Brasil

• Autor(a) principal: ANASTACIO, Daniela Bandeira
• Data de Publicação: 2019
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UFRPE
• Texto Completo: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/8182
• topic: Febre amarela; Arbovirose; Saúde pública; Vigilância ambiental; CIENCIAS AGRARIAS::MEDICINA VETERINARIA

Yellow fever (YF) has been endemic and enzootic disease in 47 countries of America and Africa. Early virus detection in sentinels Non-Human Primates (NHP) is essential to implement preventive measures to avoid the human disease, thus this study aimed to evaluate the Sylvatic Yellow Fever Surveillance Program in the State of Pernambuco. Currently, four Sentinel Units (SU) are responsible for receiving, preparing and delivering the organ samples from deceased NHP to the reference laboratory. From 2017 and 2018 it was observed less than 18% of the 185 municipalities of the state notified epizootic events, with the majority in the metropolitan region of Recife (MRR). In 2017, 37 epizootics were notified involving 67 NHP and in 2018, 79 events from 96 NHP. In both cases, over 75% of notifications were performed by SU from the MRR and Agreste, especially from the cities of Recife and Caruaru, respectively. The present study demonstrates the low rate of participation from the SU of the countryside of the state. The analysis showed around 30% of deceased NHP arriving at the SU without conditions to collect samples, demonstrating the loss at the service entrance. Moreover, only 58,3% and 47,8% of the samples from 2017 and 2018, respectively, were analyzed by immunohistochemistry, and were negative for YF virus. Consequently, the high number of pending results will not allow discarding the circulation of this arbovirus in the state of Pernambuco. This study revealed 72.7% of deceased NHP with causa mortis by trauma through physical aggression. The results showed the necessity of a greater commitment of the Municipal Health Secretaries in the process of collection and notification of deceased NHP, in order to promote an opportune surveillance of Yellow Fever in the State of Pernambuco.