Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRPE |
Texto Completo: | http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5379 |
Resumo: | The Cortical Spreading Depression (CSD) was described as a wave of electric cortical activity suppression in reply to cortical stimulation. In this work we investigate the dynamics of the cerebral activity, registered in the electrocorticogram (ECoG), from the fractal dimension of the space of phase and the coefficient of Hurst (parameter that indicates the memory presence) of the ECoG. ECoG' s had been extracellularly recorded in the cerebral cortex of nourished and malnourished rats and analysed with a PC-compatible microcomputer. In the signal of the ECoG can be observed that after the stimulation occurred an increase, during few milliseconds, of the cortical electric activity (called avalanche phenomenon), followed of a depression of this electric activity for levels lower than normal electric activity of the cortex (called cortical spreading depression - CSD phenomenon). After some minutes the cortical electric activity returns to its level of normality, that one observed before the cortical stimulation. To carry through an analysis statistics of the time series of the cortical electric activity (ECoG), two parameters had been used: (i) the fractal dimension (D)of the space of phase of ECoG and (ii) coefficient H of R/S analysis of Hurst, parameter that identifies long-range correlation (memory) in time series. During the phenomenon of the avalanche the values of the fractal dimension of the space of phase (D =1,34 ± 0,06, n= 30, for nourished animals and D= 1,31 ± 0.07, n= 32, in animals malnourished) and of the memory (H =0,52 ± 0,13, n= 30, in nourished animals and H= 0,61±0,21, n= 32, in animals malnourished) were significantly different of the values of those parameters as before (D = 1,27 ± 0,10, n= 41 and H = 0,32 ± 0,07, n= 41, for nourished animals and D= 1,18 ± 0,14, n=29 and H = 0,44 ± 0,13, n= 29 , in animals malnourished) as after the CSD (D = 1,28 ± 0,10, n= 39 and H = 0,35 ± 0,10, n= 39, for nourished animals and D= 1,15 ± 0,15, n= 30 and H = 0,43 ± 0,13, n= 30, in animals malnourished). The Shapiro-Wilks test discloses that the parameters D and H do not follow a normal distribution. Thus a non-parametric test of Kruskal-Wallis and the post-hoc test of Dunn were used in the statistic analysis. That analysis showed that in nourished animals the fractal dimension of the space of phase of the ECoG in the avalanche is different of the fractal dimension (before and after the CSD), with equal levels of significance, p≤ 0,01. The coefficientH of the ECoG in the avalanche differs also from the H´s (before of the CSD andafter the CSD), with equal levels of significance, p≤ 0,001. For the malnourished animals the parameters D and H in avalanche differs significantly from values also before and after the CSD. When animals nourished and malnourished were compared, significant differences had been observed between the values of the parameters D and H only before of the CSD. In conclusion, the electric activity of the cerebral cortex of rats nourished and malnourished during the phenomenon of the spreading depression is a chaotic, reversible process and presents memory. |
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NOGUEIRA, Romildo de AlbuquerqueSANTOS, Laélia Pumilla Botêlho Campos dosLESSA, Rosângela Paula TeixeiraBARBOSA, Catão Temístocles Freitashttp://lattes.cnpq.br/2611786721869129SANTOS, Walter2016-08-17T14:23:10Z2007-02-28SANTOS, Walter. Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos. 2007. 88 f. Dissertação (Programa de Pós-Graduação em Biometria e Estatística Aplicada) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5379The Cortical Spreading Depression (CSD) was described as a wave of electric cortical activity suppression in reply to cortical stimulation. In this work we investigate the dynamics of the cerebral activity, registered in the electrocorticogram (ECoG), from the fractal dimension of the space of phase and the coefficient of Hurst (parameter that indicates the memory presence) of the ECoG. ECoG' s had been extracellularly recorded in the cerebral cortex of nourished and malnourished rats and analysed with a PC-compatible microcomputer. In the signal of the ECoG can be observed that after the stimulation occurred an increase, during few milliseconds, of the cortical electric activity (called avalanche phenomenon), followed of a depression of this electric activity for levels lower than normal electric activity of the cortex (called cortical spreading depression - CSD phenomenon). After some minutes the cortical electric activity returns to its level of normality, that one observed before the cortical stimulation. To carry through an analysis statistics of the time series of the cortical electric activity (ECoG), two parameters had been used: (i) the fractal dimension (D)of the space of phase of ECoG and (ii) coefficient H of R/S analysis of Hurst, parameter that identifies long-range correlation (memory) in time series. During the phenomenon of the avalanche the values of the fractal dimension of the space of phase (D =1,34 ± 0,06, n= 30, for nourished animals and D= 1,31 ± 0.07, n= 32, in animals malnourished) and of the memory (H =0,52 ± 0,13, n= 30, in nourished animals and H= 0,61±0,21, n= 32, in animals malnourished) were significantly different of the values of those parameters as before (D = 1,27 ± 0,10, n= 41 and H = 0,32 ± 0,07, n= 41, for nourished animals and D= 1,18 ± 0,14, n=29 and H = 0,44 ± 0,13, n= 29 , in animals malnourished) as after the CSD (D = 1,28 ± 0,10, n= 39 and H = 0,35 ± 0,10, n= 39, for nourished animals and D= 1,15 ± 0,15, n= 30 and H = 0,43 ± 0,13, n= 30, in animals malnourished). The Shapiro-Wilks test discloses that the parameters D and H do not follow a normal distribution. Thus a non-parametric test of Kruskal-Wallis and the post-hoc test of Dunn were used in the statistic analysis. That analysis showed that in nourished animals the fractal dimension of the space of phase of the ECoG in the avalanche is different of the fractal dimension (before and after the CSD), with equal levels of significance, p≤ 0,01. The coefficientH of the ECoG in the avalanche differs also from the H´s (before of the CSD andafter the CSD), with equal levels of significance, p≤ 0,001. For the malnourished animals the parameters D and H in avalanche differs significantly from values also before and after the CSD. When animals nourished and malnourished were compared, significant differences had been observed between the values of the parameters D and H only before of the CSD. In conclusion, the electric activity of the cerebral cortex of rats nourished and malnourished during the phenomenon of the spreading depression is a chaotic, reversible process and presents memory.A Depressão Alastrante (DA) foi descrita como uma onda de supressão da atividade elétrica do córtex em resposta a estímulos corticais. Neste trabalho investigamos a dinâmica da atividade cerebral registrada no eletrocorticograma (ECoG) a partir da dimensão fractal do espaço de fase e do coeficiente de Hurst (parâmetro que indica a presença de memória) do ECoG. Os ECoG’s foram obtidos através de registros extracelulares na região cortical de ratos nutridos e desnutridos e digitalizados num microcomputador PC compatível. No sinal do ECoG pode-se observar que após o estímulo ocorreu um aumento, durante poucos milissegundos, da atividade elétrica cortical (fenômeno denominado de avalanche) seguido de uma depressão dessa atividade elétrica a nível mais baixo que da atividade elétrica normal do córtex (fenômeno denominado depressão alastrante - DA). Após alguns minutos a atividade elétrica cortical retorna ao seu nível de normalidade, aquele observado antes da estimulação cortical. Para realizar uma análise estatística da série temporal da atividade elétrica cortical (ECoG) dois parâmetros foram utilizados:i) a dimensão fractal (D) do espaço de fase do ECoG, e ii) o coeficiente H da análise R/S de Hurst, parâmetro que identifica correlação de longo alcance (memória) emséries temporais. Durante o fenômeno da avalanche os valores da dimensão fractal do espaço de fase (D =1,34 ± 0,06, n= 30, para animais nutridos e D= 1,31 ± 0,07, n= 32, em animais desnutridos) e da memória (H = 0,52 ± 0,13, n= 30, em animais nutridos e H= 0,61±0,21, n= 32, em animais desnutridos) foram significativamente diferentes dos valores dos parâmetros tanto de antes da DA (D = 1,27 ± 0,10, n= 41 e H = 0,32 ± 0,07, n= 41, para animais nutridos e D= 1,18 ± 0,14, n= 29 e H = 0,44 ± 0,13, n= 29, em animais desnutridos) como de depois da DA (D = 1,28 ± 0,10, n= 39 e H = 0,35 ± 0,10, n= 39, para animais nutridos e D= 1,15 ± 0,15, n= 30 e H = 0,43 ± 0,13, n= 30, em animais desnutridos). Um teste de normalidade de Shapiro- Wilks mostrou que os parâmetros D e H não seguem distribuições normais. Por esta razão, um teste não paramétrico de Kruskal-Wallis e um teste post-hoc de Dunn foram usados na análise estatística. Esta análise mostra que em animais nutridos a dimensão fractal do espaço de fase do ECoG na avalanche é diferente das dimensões fractais (anterior e posterior a DA) com níveis de significância inferiores a 1%. O coeficiente H do ECoG na avalanche também difere dos H´s (antes da DA e após a DA) com níveis de significância inferiores a 0,1%. Para os animaisdesnutridos os parâmetros D e H na avalanche também diferiram significativamente dos seus valores antes e depois da DA. Quando animais nutridos e desnutridos foram comparados, diferenças significativas foram observadas entre os valores dos parâmetros D e H somente antes da DA. Concluindo assim, que a atividade elétrica do córtex cerebral de ratos nutridos e desnutridos durante o fenômeno da depressão alastrante é um processo caótico, reversível e apresenta memória.Submitted by (ana.araujo@ufrpe.br) on 2016-08-17T14:23:09Z No. of bitstreams: 1 Walter Santos.pdf: 5031272 bytes, checksum: 3d2990a03fd5d064b37a30e3665f9ecf (MD5)Made available in DSpace on 2016-08-17T14:23:10Z (GMT). No. of bitstreams: 1 Walter Santos.pdf: 5031272 bytes, checksum: 3d2990a03fd5d064b37a30e3665f9ecf (MD5) Previous issue date: 2007-02-28application/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em Biometria e Estatística AplicadaUFRPEBrasilDepartamento de Estatística e InformáticaEletrocorticogramaDepressão alastranteDimensão fractalCoeficiente de HurstElectrocorticogramCortical spreading depressionFractal dimensionHurst coefficientCIENCIAS EXATAS E DA TERRA::PROBABILIDADE E ESTATISTICAAnálise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis768382242446187918600600600-6774555140396120501-5836407828185143517info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRPEinstname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPELICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/5379/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51ORIGINALWalter Santos.pdfWalter Santos.pdfapplication/pdf5031272http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/5379/2/Walter+Santos.pdf3d2990a03fd5d064b37a30e3665f9ecfMD52tede2/53792024-02-23 15:20:10.776oai:tede2: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Biblioteca Digital de Teses e Dissertaçõeshttp://www.tede2.ufrpe.br:8080/tede/PUBhttp://www.tede2.ufrpe.br:8080/oai/requestbdtd@ufrpe.br ||bdtd@ufrpe.bropendoar:2024-02-23T18:20:10Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE)false |
dc.title.por.fl_str_mv |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
title |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
spellingShingle |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos SANTOS, Walter Eletrocorticograma Depressão alastrante Dimensão fractal Coeficiente de Hurst Electrocorticogram Cortical spreading depression Fractal dimension Hurst coefficient CIENCIAS EXATAS E DA TERRA::PROBABILIDADE E ESTATISTICA |
title_short |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
title_full |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
title_fullStr |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
title_full_unstemmed |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
title_sort |
Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos |
author |
SANTOS, Walter |
author_facet |
SANTOS, Walter |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
NOGUEIRA, Romildo de Albuquerque |
dc.contributor.referee1.fl_str_mv |
SANTOS, Laélia Pumilla Botêlho Campos dos |
dc.contributor.referee2.fl_str_mv |
LESSA, Rosângela Paula Teixeira |
dc.contributor.referee3.fl_str_mv |
BARBOSA, Catão Temístocles Freitas |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2611786721869129 |
dc.contributor.author.fl_str_mv |
SANTOS, Walter |
contributor_str_mv |
NOGUEIRA, Romildo de Albuquerque SANTOS, Laélia Pumilla Botêlho Campos dos LESSA, Rosângela Paula Teixeira BARBOSA, Catão Temístocles Freitas |
dc.subject.por.fl_str_mv |
Eletrocorticograma Depressão alastrante Dimensão fractal Coeficiente de Hurst |
topic |
Eletrocorticograma Depressão alastrante Dimensão fractal Coeficiente de Hurst Electrocorticogram Cortical spreading depression Fractal dimension Hurst coefficient CIENCIAS EXATAS E DA TERRA::PROBABILIDADE E ESTATISTICA |
dc.subject.eng.fl_str_mv |
Electrocorticogram Cortical spreading depression Fractal dimension Hurst coefficient |
dc.subject.cnpq.fl_str_mv |
CIENCIAS EXATAS E DA TERRA::PROBABILIDADE E ESTATISTICA |
description |
The Cortical Spreading Depression (CSD) was described as a wave of electric cortical activity suppression in reply to cortical stimulation. In this work we investigate the dynamics of the cerebral activity, registered in the electrocorticogram (ECoG), from the fractal dimension of the space of phase and the coefficient of Hurst (parameter that indicates the memory presence) of the ECoG. ECoG' s had been extracellularly recorded in the cerebral cortex of nourished and malnourished rats and analysed with a PC-compatible microcomputer. In the signal of the ECoG can be observed that after the stimulation occurred an increase, during few milliseconds, of the cortical electric activity (called avalanche phenomenon), followed of a depression of this electric activity for levels lower than normal electric activity of the cortex (called cortical spreading depression - CSD phenomenon). After some minutes the cortical electric activity returns to its level of normality, that one observed before the cortical stimulation. To carry through an analysis statistics of the time series of the cortical electric activity (ECoG), two parameters had been used: (i) the fractal dimension (D)of the space of phase of ECoG and (ii) coefficient H of R/S analysis of Hurst, parameter that identifies long-range correlation (memory) in time series. During the phenomenon of the avalanche the values of the fractal dimension of the space of phase (D =1,34 ± 0,06, n= 30, for nourished animals and D= 1,31 ± 0.07, n= 32, in animals malnourished) and of the memory (H =0,52 ± 0,13, n= 30, in nourished animals and H= 0,61±0,21, n= 32, in animals malnourished) were significantly different of the values of those parameters as before (D = 1,27 ± 0,10, n= 41 and H = 0,32 ± 0,07, n= 41, for nourished animals and D= 1,18 ± 0,14, n=29 and H = 0,44 ± 0,13, n= 29 , in animals malnourished) as after the CSD (D = 1,28 ± 0,10, n= 39 and H = 0,35 ± 0,10, n= 39, for nourished animals and D= 1,15 ± 0,15, n= 30 and H = 0,43 ± 0,13, n= 30, in animals malnourished). The Shapiro-Wilks test discloses that the parameters D and H do not follow a normal distribution. Thus a non-parametric test of Kruskal-Wallis and the post-hoc test of Dunn were used in the statistic analysis. That analysis showed that in nourished animals the fractal dimension of the space of phase of the ECoG in the avalanche is different of the fractal dimension (before and after the CSD), with equal levels of significance, p≤ 0,01. The coefficientH of the ECoG in the avalanche differs also from the H´s (before of the CSD andafter the CSD), with equal levels of significance, p≤ 0,001. For the malnourished animals the parameters D and H in avalanche differs significantly from values also before and after the CSD. When animals nourished and malnourished were compared, significant differences had been observed between the values of the parameters D and H only before of the CSD. In conclusion, the electric activity of the cerebral cortex of rats nourished and malnourished during the phenomenon of the spreading depression is a chaotic, reversible process and presents memory. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-02-28 |
dc.date.accessioned.fl_str_mv |
2016-08-17T14:23:10Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SANTOS, Walter. Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos. 2007. 88 f. Dissertação (Programa de Pós-Graduação em Biometria e Estatística Aplicada) - Universidade Federal Rural de Pernambuco, Recife. |
dc.identifier.uri.fl_str_mv |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5379 |
identifier_str_mv |
SANTOS, Walter. Análise estatística do eletrocorticograma durante o fenômeno da depressão alastrante em córtex cerebral de ratos nutridos e desnutridos. 2007. 88 f. Dissertação (Programa de Pós-Graduação em Biometria e Estatística Aplicada) - Universidade Federal Rural de Pernambuco, Recife. |
url |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5379 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
768382242446187918 |
dc.relation.confidence.fl_str_mv |
600 600 600 |
dc.relation.department.fl_str_mv |
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eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal Rural de Pernambuco |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Biometria e Estatística Aplicada |
dc.publisher.initials.fl_str_mv |
UFRPE |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Departamento de Estatística e Informática |
publisher.none.fl_str_mv |
Universidade Federal Rural de Pernambuco |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da UFRPE instname:Universidade Federal Rural de Pernambuco (UFRPE) instacron:UFRPE |
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Universidade Federal Rural de Pernambuco (UFRPE) |
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UFRPE |
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UFRPE |
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Biblioteca Digital de Teses e Dissertações da UFRPE |
collection |
Biblioteca Digital de Teses e Dissertações da UFRPE |
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http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/5379/1/license.txt http://www.tede2.ufrpe.br:8080/tede2/bitstream/tede2/5379/2/Walter+Santos.pdf |
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Biblioteca Digital de Teses e Dissertações da UFRPE - Universidade Federal Rural de Pernambuco (UFRPE) |
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bdtd@ufrpe.br ||bdtd@ufrpe.br |
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