Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae

Detalhes bibliográficos
Autor(a) principal: HOLANDA, Luís Eduardo Gomes de
Data de Publicação: 2017
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFRPE
Texto Completo: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924
Resumo: Throughout the centuries, plants have been used and studied because they contain several substances that are responsible for pharmacological actions. The plant are widely used in folk medicine due to the biological properties of its fruits, is the Morinda citrifolia L., popularly known as noni. The Morinda citrifolia is member of the family Rubiaceae. It is a plant native to Southeast Asia and has received good acceptance in Brazil due to its biological activities. Morinda citrifolia has exploded in population and use; and because of it, carefully studied. Inserted in this context, the present work has the objective to present the chemical characterization of the essential oils of the different plant tissues and the evaluation of its antimicrobial potential. The essential oils of the Morinda citrifolia were obtained by hydrodistillation and the identification of their chemical constituents is determined by GC-MS. In short, the stem oil p-Menta-1- (7), 8-diene was identified as the major compound with a relative percentage of 9.64%, followed by the compound allyl decanoate (7.50%). In the leaf oil, phytol was identified as the major compound with 49.32%. In the essential fruit oil, octanoic acid was identified with 38.68%, hexanoic acid (20,00%) and methyl octanoate (16.98%). After the esterification reaction used by the carboxylic acids, the essential oils were methyl hexanoate (12.15%), methyl octanoate (83.38%) and methyl decanoate (4.46%). The essential oil of the fruits showed moderate to strong antimicrobial activity, being observed a greater activity against the fungi Candida albicans and Candida utilis with MIC from 39 μg/ml to 78.1 μg/ml, respectively. The essential oil of the fruits showed activity against all the bacteria tested, with a lower MIC of 156 μg/ml observed for Bacillus subtilis and the highest of 625 μg/ml for Pseudomonas aeruginosa. The results obtained contribute to the chemical and biological knowledge of Morinda citrifolia, which is widely reported as an excellent plant for therapeutic purposes.
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spelling RAMOS, Clécio SouzaAQUINO, Fabiana da SilvaMORAES, Marcílio Martins deOLIVEIRA, Lourinalda Luíza Dantas da Silva Selva deFREITAS FILHO, João Rufino dehttp://lattes.cnpq.br/0987602229023046HOLANDA, Luís Eduardo Gomes de2019-04-04T13:27:03Z2017-07-28HOLANDA, Luís Eduardo Gomes de. Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae. 2017. 81 f. Dissertação (Programa de Pós-Graduação em Química) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924Throughout the centuries, plants have been used and studied because they contain several substances that are responsible for pharmacological actions. The plant are widely used in folk medicine due to the biological properties of its fruits, is the Morinda citrifolia L., popularly known as noni. The Morinda citrifolia is member of the family Rubiaceae. It is a plant native to Southeast Asia and has received good acceptance in Brazil due to its biological activities. Morinda citrifolia has exploded in population and use; and because of it, carefully studied. Inserted in this context, the present work has the objective to present the chemical characterization of the essential oils of the different plant tissues and the evaluation of its antimicrobial potential. The essential oils of the Morinda citrifolia were obtained by hydrodistillation and the identification of their chemical constituents is determined by GC-MS. In short, the stem oil p-Menta-1- (7), 8-diene was identified as the major compound with a relative percentage of 9.64%, followed by the compound allyl decanoate (7.50%). In the leaf oil, phytol was identified as the major compound with 49.32%. In the essential fruit oil, octanoic acid was identified with 38.68%, hexanoic acid (20,00%) and methyl octanoate (16.98%). After the esterification reaction used by the carboxylic acids, the essential oils were methyl hexanoate (12.15%), methyl octanoate (83.38%) and methyl decanoate (4.46%). The essential oil of the fruits showed moderate to strong antimicrobial activity, being observed a greater activity against the fungi Candida albicans and Candida utilis with MIC from 39 μg/ml to 78.1 μg/ml, respectively. The essential oil of the fruits showed activity against all the bacteria tested, with a lower MIC of 156 μg/ml observed for Bacillus subtilis and the highest of 625 μg/ml for Pseudomonas aeruginosa. The results obtained contribute to the chemical and biological knowledge of Morinda citrifolia, which is widely reported as an excellent plant for therapeutic purposes.Ao longo dos séculos as plantas vêem sendo utilizadas e estudadas por conterem diversas substâncias que são responsáveis por ações farmacológicas. A planta é amplamente usada na medicina popular devido às propriedades biológicas de seus frutos é a Morinda citrifolia L., conhecida popularmente como noni. A Morinda citrifolia pertencente à família Rubiaceae é uma planta nativa do sudeste Asiático tem recebido atenção no Brasil devido as suas atividades biológicas, sendo difundidas na população e em estudos relatados previamente. Inserido neste contexto, o presente trabalho foi direcionado para caracterização química dos óleos essências dos diferentes tecidos vegetais da planta e avaliação do seu potencial antimicrobiano. Os óleos essências da Morinda citrifolia foram obtidos por hidrodestilação e a identificação de seus constituintes químicos determinada por CG-EM. No óleo essencial dos caules foi identificado a p-Menta-1-(7),8-dieno como composto majoritário com percentagem relativa de 9,64%, seguido pelo composto decanoato de alila (7,50%). No óleo das folhas o fitol foi identificado como composto majoritário com 49,32%. No óleo essencial dos frutos foi identificado o ácido octanóico com 38,68%, o ácido hexanóico (20,00%) e o octanoato de metila (16,98%). Óleo essencial dos frutos, após reação de esterificação para confirmação dos ácidos carboxílicos, apresentou como compostos majoritários os ésteres hexanoato de metila (12,15%), octanoato de metila (83,38%) e o decanoato de metila (4,46%). O óleo essencial dos frutos mostrou atividade antimicrobiana de forte a moderada, sendo observada uma maior atividade frente aos fungos Candida albicans e Candida utilis com CMI de 39 μg/ml a 78,1 μg/ml, respectivamente. O óleo essencial dos frutos mostrou atividade frente a todas as bactérias testadas, com menor CMI de 156 μg/ml observada para a Bacillus subtilis e a maior de 625 μg/ml para a Pseudomonas aeruginosa. Os resultados obtidos contribuem para o conhecimento químico e biológico da M. citrifolia, que é amplamente divulgada na população como uma excelente planta para fins terapêuticos.Submitted by Mario BC (mario@bc.ufrpe.br) on 2019-04-04T13:27:03Z No. of bitstreams: 1 Luis Eduardo Gomes de Holanda.pdf: 2642284 bytes, checksum: c91e713f697b1893e35ed0cb0376bc5a (MD5)Made available in DSpace on 2019-04-04T13:27:03Z (GMT). No. of bitstreams: 1 Luis Eduardo Gomes de Holanda.pdf: 2642284 bytes, checksum: c91e713f697b1893e35ed0cb0376bc5a (MD5) Previous issue date: 2017-07-28Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em QuímicaUFRPEBrasilDepartamento de QuímicaÓleo essencialMorinda citrifoliaAtividade antimicrobianaCIENCIAS EXATAS E DA TERRA::QUIMICAComposição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. 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dc.title.por.fl_str_mv Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
title Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
spellingShingle Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
HOLANDA, Luís Eduardo Gomes de
Óleo essencial
Morinda citrifolia
Atividade antimicrobiana
CIENCIAS EXATAS E DA TERRA::QUIMICA
title_short Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
title_full Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
title_fullStr Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
title_full_unstemmed Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
title_sort Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
author HOLANDA, Luís Eduardo Gomes de
author_facet HOLANDA, Luís Eduardo Gomes de
author_role author
dc.contributor.advisor1.fl_str_mv RAMOS, Clécio Souza
dc.contributor.referee1.fl_str_mv AQUINO, Fabiana da Silva
dc.contributor.referee2.fl_str_mv MORAES, Marcílio Martins de
dc.contributor.referee3.fl_str_mv OLIVEIRA, Lourinalda Luíza Dantas da Silva Selva de
dc.contributor.referee4.fl_str_mv FREITAS FILHO, João Rufino de
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0987602229023046
dc.contributor.author.fl_str_mv HOLANDA, Luís Eduardo Gomes de
contributor_str_mv RAMOS, Clécio Souza
AQUINO, Fabiana da Silva
MORAES, Marcílio Martins de
OLIVEIRA, Lourinalda Luíza Dantas da Silva Selva de
FREITAS FILHO, João Rufino de
dc.subject.por.fl_str_mv Óleo essencial
Morinda citrifolia
Atividade antimicrobiana
topic Óleo essencial
Morinda citrifolia
Atividade antimicrobiana
CIENCIAS EXATAS E DA TERRA::QUIMICA
dc.subject.cnpq.fl_str_mv CIENCIAS EXATAS E DA TERRA::QUIMICA
description Throughout the centuries, plants have been used and studied because they contain several substances that are responsible for pharmacological actions. The plant are widely used in folk medicine due to the biological properties of its fruits, is the Morinda citrifolia L., popularly known as noni. The Morinda citrifolia is member of the family Rubiaceae. It is a plant native to Southeast Asia and has received good acceptance in Brazil due to its biological activities. Morinda citrifolia has exploded in population and use; and because of it, carefully studied. Inserted in this context, the present work has the objective to present the chemical characterization of the essential oils of the different plant tissues and the evaluation of its antimicrobial potential. The essential oils of the Morinda citrifolia were obtained by hydrodistillation and the identification of their chemical constituents is determined by GC-MS. In short, the stem oil p-Menta-1- (7), 8-diene was identified as the major compound with a relative percentage of 9.64%, followed by the compound allyl decanoate (7.50%). In the leaf oil, phytol was identified as the major compound with 49.32%. In the essential fruit oil, octanoic acid was identified with 38.68%, hexanoic acid (20,00%) and methyl octanoate (16.98%). After the esterification reaction used by the carboxylic acids, the essential oils were methyl hexanoate (12.15%), methyl octanoate (83.38%) and methyl decanoate (4.46%). The essential oil of the fruits showed moderate to strong antimicrobial activity, being observed a greater activity against the fungi Candida albicans and Candida utilis with MIC from 39 μg/ml to 78.1 μg/ml, respectively. The essential oil of the fruits showed activity against all the bacteria tested, with a lower MIC of 156 μg/ml observed for Bacillus subtilis and the highest of 625 μg/ml for Pseudomonas aeruginosa. The results obtained contribute to the chemical and biological knowledge of Morinda citrifolia, which is widely reported as an excellent plant for therapeutic purposes.
publishDate 2017
dc.date.issued.fl_str_mv 2017-07-28
dc.date.accessioned.fl_str_mv 2019-04-04T13:27:03Z
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dc.identifier.citation.fl_str_mv HOLANDA, Luís Eduardo Gomes de. Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae. 2017. 81 f. Dissertação (Programa de Pós-Graduação em Química) - Universidade Federal Rural de Pernambuco, Recife.
dc.identifier.uri.fl_str_mv http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924
identifier_str_mv HOLANDA, Luís Eduardo Gomes de. Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae. 2017. 81 f. Dissertação (Programa de Pós-Graduação em Química) - Universidade Federal Rural de Pernambuco, Recife.
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dc.publisher.department.fl_str_mv Departamento de Química
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