Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRPE |
Texto Completo: | http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924 |
Resumo: | Throughout the centuries, plants have been used and studied because they contain several substances that are responsible for pharmacological actions. The plant are widely used in folk medicine due to the biological properties of its fruits, is the Morinda citrifolia L., popularly known as noni. The Morinda citrifolia is member of the family Rubiaceae. It is a plant native to Southeast Asia and has received good acceptance in Brazil due to its biological activities. Morinda citrifolia has exploded in population and use; and because of it, carefully studied. Inserted in this context, the present work has the objective to present the chemical characterization of the essential oils of the different plant tissues and the evaluation of its antimicrobial potential. The essential oils of the Morinda citrifolia were obtained by hydrodistillation and the identification of their chemical constituents is determined by GC-MS. In short, the stem oil p-Menta-1- (7), 8-diene was identified as the major compound with a relative percentage of 9.64%, followed by the compound allyl decanoate (7.50%). In the leaf oil, phytol was identified as the major compound with 49.32%. In the essential fruit oil, octanoic acid was identified with 38.68%, hexanoic acid (20,00%) and methyl octanoate (16.98%). After the esterification reaction used by the carboxylic acids, the essential oils were methyl hexanoate (12.15%), methyl octanoate (83.38%) and methyl decanoate (4.46%). The essential oil of the fruits showed moderate to strong antimicrobial activity, being observed a greater activity against the fungi Candida albicans and Candida utilis with MIC from 39 μg/ml to 78.1 μg/ml, respectively. The essential oil of the fruits showed activity against all the bacteria tested, with a lower MIC of 156 μg/ml observed for Bacillus subtilis and the highest of 625 μg/ml for Pseudomonas aeruginosa. The results obtained contribute to the chemical and biological knowledge of Morinda citrifolia, which is widely reported as an excellent plant for therapeutic purposes. |
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RAMOS, Clécio SouzaAQUINO, Fabiana da SilvaMORAES, Marcílio Martins deOLIVEIRA, Lourinalda Luíza Dantas da Silva Selva deFREITAS FILHO, João Rufino dehttp://lattes.cnpq.br/0987602229023046HOLANDA, Luís Eduardo Gomes de2019-04-04T13:27:03Z2017-07-28HOLANDA, Luís Eduardo Gomes de. Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae. 2017. 81 f. Dissertação (Programa de Pós-Graduação em Química) - Universidade Federal Rural de Pernambuco, Recife.http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924Throughout the centuries, plants have been used and studied because they contain several substances that are responsible for pharmacological actions. The plant are widely used in folk medicine due to the biological properties of its fruits, is the Morinda citrifolia L., popularly known as noni. The Morinda citrifolia is member of the family Rubiaceae. It is a plant native to Southeast Asia and has received good acceptance in Brazil due to its biological activities. Morinda citrifolia has exploded in population and use; and because of it, carefully studied. Inserted in this context, the present work has the objective to present the chemical characterization of the essential oils of the different plant tissues and the evaluation of its antimicrobial potential. The essential oils of the Morinda citrifolia were obtained by hydrodistillation and the identification of their chemical constituents is determined by GC-MS. In short, the stem oil p-Menta-1- (7), 8-diene was identified as the major compound with a relative percentage of 9.64%, followed by the compound allyl decanoate (7.50%). In the leaf oil, phytol was identified as the major compound with 49.32%. In the essential fruit oil, octanoic acid was identified with 38.68%, hexanoic acid (20,00%) and methyl octanoate (16.98%). After the esterification reaction used by the carboxylic acids, the essential oils were methyl hexanoate (12.15%), methyl octanoate (83.38%) and methyl decanoate (4.46%). The essential oil of the fruits showed moderate to strong antimicrobial activity, being observed a greater activity against the fungi Candida albicans and Candida utilis with MIC from 39 μg/ml to 78.1 μg/ml, respectively. The essential oil of the fruits showed activity against all the bacteria tested, with a lower MIC of 156 μg/ml observed for Bacillus subtilis and the highest of 625 μg/ml for Pseudomonas aeruginosa. The results obtained contribute to the chemical and biological knowledge of Morinda citrifolia, which is widely reported as an excellent plant for therapeutic purposes.Ao longo dos séculos as plantas vêem sendo utilizadas e estudadas por conterem diversas substâncias que são responsáveis por ações farmacológicas. A planta é amplamente usada na medicina popular devido às propriedades biológicas de seus frutos é a Morinda citrifolia L., conhecida popularmente como noni. A Morinda citrifolia pertencente à família Rubiaceae é uma planta nativa do sudeste Asiático tem recebido atenção no Brasil devido as suas atividades biológicas, sendo difundidas na população e em estudos relatados previamente. Inserido neste contexto, o presente trabalho foi direcionado para caracterização química dos óleos essências dos diferentes tecidos vegetais da planta e avaliação do seu potencial antimicrobiano. Os óleos essências da Morinda citrifolia foram obtidos por hidrodestilação e a identificação de seus constituintes químicos determinada por CG-EM. No óleo essencial dos caules foi identificado a p-Menta-1-(7),8-dieno como composto majoritário com percentagem relativa de 9,64%, seguido pelo composto decanoato de alila (7,50%). No óleo das folhas o fitol foi identificado como composto majoritário com 49,32%. No óleo essencial dos frutos foi identificado o ácido octanóico com 38,68%, o ácido hexanóico (20,00%) e o octanoato de metila (16,98%). Óleo essencial dos frutos, após reação de esterificação para confirmação dos ácidos carboxílicos, apresentou como compostos majoritários os ésteres hexanoato de metila (12,15%), octanoato de metila (83,38%) e o decanoato de metila (4,46%). O óleo essencial dos frutos mostrou atividade antimicrobiana de forte a moderada, sendo observada uma maior atividade frente aos fungos Candida albicans e Candida utilis com CMI de 39 μg/ml a 78,1 μg/ml, respectivamente. O óleo essencial dos frutos mostrou atividade frente a todas as bactérias testadas, com menor CMI de 156 μg/ml observada para a Bacillus subtilis e a maior de 625 μg/ml para a Pseudomonas aeruginosa. Os resultados obtidos contribuem para o conhecimento químico e biológico da M. citrifolia, que é amplamente divulgada na população como uma excelente planta para fins terapêuticos.Submitted by Mario BC (mario@bc.ufrpe.br) on 2019-04-04T13:27:03Z No. of bitstreams: 1 Luis Eduardo Gomes de Holanda.pdf: 2642284 bytes, checksum: c91e713f697b1893e35ed0cb0376bc5a (MD5)Made available in DSpace on 2019-04-04T13:27:03Z (GMT). No. of bitstreams: 1 Luis Eduardo Gomes de Holanda.pdf: 2642284 bytes, checksum: c91e713f697b1893e35ed0cb0376bc5a (MD5) Previous issue date: 2017-07-28Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal Rural de PernambucoPrograma de Pós-Graduação em QuímicaUFRPEBrasilDepartamento de QuímicaÓleo essencialMorinda citrifoliaAtividade antimicrobianaCIENCIAS EXATAS E DA TERRA::QUIMICAComposição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. 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dc.title.por.fl_str_mv |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
title |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
spellingShingle |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae HOLANDA, Luís Eduardo Gomes de Óleo essencial Morinda citrifolia Atividade antimicrobiana CIENCIAS EXATAS E DA TERRA::QUIMICA |
title_short |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
title_full |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
title_fullStr |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
title_full_unstemmed |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
title_sort |
Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae |
author |
HOLANDA, Luís Eduardo Gomes de |
author_facet |
HOLANDA, Luís Eduardo Gomes de |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
RAMOS, Clécio Souza |
dc.contributor.referee1.fl_str_mv |
AQUINO, Fabiana da Silva |
dc.contributor.referee2.fl_str_mv |
MORAES, Marcílio Martins de |
dc.contributor.referee3.fl_str_mv |
OLIVEIRA, Lourinalda Luíza Dantas da Silva Selva de |
dc.contributor.referee4.fl_str_mv |
FREITAS FILHO, João Rufino de |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0987602229023046 |
dc.contributor.author.fl_str_mv |
HOLANDA, Luís Eduardo Gomes de |
contributor_str_mv |
RAMOS, Clécio Souza AQUINO, Fabiana da Silva MORAES, Marcílio Martins de OLIVEIRA, Lourinalda Luíza Dantas da Silva Selva de FREITAS FILHO, João Rufino de |
dc.subject.por.fl_str_mv |
Óleo essencial Morinda citrifolia Atividade antimicrobiana |
topic |
Óleo essencial Morinda citrifolia Atividade antimicrobiana CIENCIAS EXATAS E DA TERRA::QUIMICA |
dc.subject.cnpq.fl_str_mv |
CIENCIAS EXATAS E DA TERRA::QUIMICA |
description |
Throughout the centuries, plants have been used and studied because they contain several substances that are responsible for pharmacological actions. The plant are widely used in folk medicine due to the biological properties of its fruits, is the Morinda citrifolia L., popularly known as noni. The Morinda citrifolia is member of the family Rubiaceae. It is a plant native to Southeast Asia and has received good acceptance in Brazil due to its biological activities. Morinda citrifolia has exploded in population and use; and because of it, carefully studied. Inserted in this context, the present work has the objective to present the chemical characterization of the essential oils of the different plant tissues and the evaluation of its antimicrobial potential. The essential oils of the Morinda citrifolia were obtained by hydrodistillation and the identification of their chemical constituents is determined by GC-MS. In short, the stem oil p-Menta-1- (7), 8-diene was identified as the major compound with a relative percentage of 9.64%, followed by the compound allyl decanoate (7.50%). In the leaf oil, phytol was identified as the major compound with 49.32%. In the essential fruit oil, octanoic acid was identified with 38.68%, hexanoic acid (20,00%) and methyl octanoate (16.98%). After the esterification reaction used by the carboxylic acids, the essential oils were methyl hexanoate (12.15%), methyl octanoate (83.38%) and methyl decanoate (4.46%). The essential oil of the fruits showed moderate to strong antimicrobial activity, being observed a greater activity against the fungi Candida albicans and Candida utilis with MIC from 39 μg/ml to 78.1 μg/ml, respectively. The essential oil of the fruits showed activity against all the bacteria tested, with a lower MIC of 156 μg/ml observed for Bacillus subtilis and the highest of 625 μg/ml for Pseudomonas aeruginosa. The results obtained contribute to the chemical and biological knowledge of Morinda citrifolia, which is widely reported as an excellent plant for therapeutic purposes. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017-07-28 |
dc.date.accessioned.fl_str_mv |
2019-04-04T13:27:03Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/masterThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
HOLANDA, Luís Eduardo Gomes de. Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae. 2017. 81 f. Dissertação (Programa de Pós-Graduação em Química) - Universidade Federal Rural de Pernambuco, Recife. |
dc.identifier.uri.fl_str_mv |
http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924 |
identifier_str_mv |
HOLANDA, Luís Eduardo Gomes de. Composição química e atividade antimicrobiana dos óleos essenciais dos diferentes tecidos de Morinda citrifolia Linn. Rubiaceae. 2017. 81 f. Dissertação (Programa de Pós-Graduação em Química) - Universidade Federal Rural de Pernambuco, Recife. |
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http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/7924 |
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Universidade Federal Rural de Pernambuco |
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Universidade Federal Rural de Pernambuco |
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