Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio
Autor(a) principal: | |
---|---|
Data de Publicação: | 2019 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da USC |
Texto Completo: | https://tede2.usc.br:8443/handle/tede/459 |
Resumo: | Titanium dioxide is extremely important because of its physical and chemical properties and different types of crystalline morphology (Anatase, Rutile and Broquita). It is currently used in the fields of science, environmental and energy. The nanoparticulate form has advantages or specificities, since this material achieves a more efficient relation between surface / volume, causing it to have a larger area of action mainly in the use of its photocatalytic properties. In this work the synthesis of the titanium dioxide nanoparticle was carried out using the Pechini method, varying the synthesis temperature in order to observe the changes in its morphology and physico-chemical properties. The nanoparticles (NPs) synthesized as well as the commercial titanium dioxide were characterized by X-ray diffraction (XRD) and morphologically by Scanning Electron Microscopy (SEM). Its ability to generate hydroxyl radicals was determined by Electron Spin Resonance (RSE). Since the Aspergillus niger fungus tends to develop in humid environments bringing harm to society and the environment, this work proposed the use of NPs as an antifungal agent. The antifungal activities of the materials were evaluated through the Minimum Inhibitory Concentration (MIC). The DRX showed that the obtained phase with a temperature of 400ºC is Anatase and presents a higher ratio surface / volume, the diameter of the smaller crystallite of 7.74nm, the other samples analyzed were crystallographically presented as Rutilo and its diameter of 34,89nm. The DLS of the TiO2A sample showed that the nanoparticles were in the diameter range of 60 to 120 nm. The experiments with RSE showed that this crystalline phase Anatase presents better photocatalytic characteristics than the other samples, since its relation surface / volume is bigger than the other samples. The CIM showed that Anatase sample obtained a more expressive result in the antifungal aspect where the concentration (750ug / ml) to eliminate the fungus was smaller than the other samples. |
id |
USC_b76ddf93720ce81b27c37c3711200d2c |
---|---|
oai_identifier_str |
oai:localhost:tede/459 |
network_acronym_str |
USC |
network_name_str |
Biblioteca Digital de Teses e Dissertações da USC |
repository_id_str |
|
spelling |
Kinoshita, Angela Mitie Otta10915343819http://lattes.cnpq.br/9357035017384643Chaves, Marcia Rodrigues De Morais18088282837http://lattes.cnpq.br/462303898764552844131325802http://lattes.cnpq.br/8907082465672671Michellotti, Michel Augusto Massambani2019-05-10T18:51:41Z2019-02-18Michellotti, Michel Augusto Massambani. Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio. 2019. 36f. Dissertação (Mestrado em Ciência e Tecnologia Ambiental) - Universidade do Sagrado Coração, Bauru, 2019 .https://tede2.usc.br:8443/handle/tede/459Titanium dioxide is extremely important because of its physical and chemical properties and different types of crystalline morphology (Anatase, Rutile and Broquita). It is currently used in the fields of science, environmental and energy. The nanoparticulate form has advantages or specificities, since this material achieves a more efficient relation between surface / volume, causing it to have a larger area of action mainly in the use of its photocatalytic properties. In this work the synthesis of the titanium dioxide nanoparticle was carried out using the Pechini method, varying the synthesis temperature in order to observe the changes in its morphology and physico-chemical properties. The nanoparticles (NPs) synthesized as well as the commercial titanium dioxide were characterized by X-ray diffraction (XRD) and morphologically by Scanning Electron Microscopy (SEM). Its ability to generate hydroxyl radicals was determined by Electron Spin Resonance (RSE). Since the Aspergillus niger fungus tends to develop in humid environments bringing harm to society and the environment, this work proposed the use of NPs as an antifungal agent. The antifungal activities of the materials were evaluated through the Minimum Inhibitory Concentration (MIC). The DRX showed that the obtained phase with a temperature of 400ºC is Anatase and presents a higher ratio surface / volume, the diameter of the smaller crystallite of 7.74nm, the other samples analyzed were crystallographically presented as Rutilo and its diameter of 34,89nm. The DLS of the TiO2A sample showed that the nanoparticles were in the diameter range of 60 to 120 nm. The experiments with RSE showed that this crystalline phase Anatase presents better photocatalytic characteristics than the other samples, since its relation surface / volume is bigger than the other samples. The CIM showed that Anatase sample obtained a more expressive result in the antifungal aspect where the concentration (750ug / ml) to eliminate the fungus was smaller than the other samples.O dióxido de titânio apresenta suma importância devido suas propriedades físicos-químicas e diferentes tipos de morfologia cristalina (Anatase, Rutilo e Broquita), sendo atualmente empregado em campos da ciência, na área ambiental e energética. A forma nanoparticulada tem vantagens ou especificidades, pois esse material consegue uma relação maiseficiente entre superfície/volume fazendo com que ela possua uma maior área de atuação principalmente no uso das suas propriedades fotocatalíticas. Nesse trabalho foi realizada a sintetização da nanopartícula de dióxido de titânio através do método Pechini, variando-se a temperatura de síntese fim de se observar as mudanças em sua morfologia e propriedades físico-quimicas. As nanopartículas (NPs) sintetizadas bem como o dióxido de titânio comercial foram caracterizadas cristalograficamente pela Difração de Raios-X (DRX) e morfologicamente pela Microscopia Eletrônica de Varredura (MEV). A sua capacidade de gerar radicais hidroxilas foi determinada por Ressonância de Spin Eletrônico (RSE). Uma vez que o fungo Aspergillus niger tende a se desenvolver em ambientes úmidos trazendo malefícios para a sociedade e ambiente, este trabalho propôs o uso das NPs como um agente antifúngico. As atividades antifúngicas dos materiais foram avaliadas através da Concentração Inibitória Mínima (CIM). A DRX demonstrou que a fase obtida com temperatura de 400ºC é a Anatase e apresenta maior razão superfície/volume, o diâmetro do menor cristalito de 7,74nm, as outras amostras analisadas foram cristalograficamente apresentada como Rutilo e seu diâmetro de 34,89 nm. O DLS da amostra TiO2A apresentou que as nanoparticulas ficaram na faixa de diâmetro de 60 á 120 nm. Os experimentos com RSE mostraram que esta fase cristalina Anatase apresenta melhores características fotocatalíticas do que as outras amostras, uma vez que sua relação superfice/volume é maior que as outras amostras. O CIM apresentou que amostra Anatase obteve resultado mais expressivo no aspecto antifúngico onde a concentração (750ug/ml) para eliminar o fungo foi menor que as outras amostras.Submitted by Lidyane Lima (lidyane.lima@usc.br) on 2019-05-10T18:51:41Z No. of bitstreams: 1 Sintese, caracterizacao e potencial uso como agente antifungico de nanoparticulas de dioxido de titanio (227046).pdf: 4140236 bytes, checksum: 36dbcaa6b2373a43232f8b0253f719ac (MD5)Made available in DSpace on 2019-05-10T18:51:41Z (GMT). No. of bitstreams: 1 Sintese, caracterizacao e potencial uso como agente antifungico de nanoparticulas de dioxido de titanio (227046).pdf: 4140236 bytes, checksum: 36dbcaa6b2373a43232f8b0253f719ac (MD5) Previous issue date: 2019-02-18Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade do Sagrado CoraçãoCiência e Tecnologia AmbientalUSCBrasilCiências da Saúde e BiológicasMétodo PechiniFotocatáliseAspergillus nigerAntifúngicoPechini methodPhotocatalystAspergillus nigerAntifungalCIENCIAS EXATAS E DA TERRASíntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânioSynthesis, characterization and potential use as antifungal agent of titanium dioxide nanoparticlesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8879801746566820546600600600600-753428887677182963-45373260596047840162075167498588264571info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da USCinstname:Universidade do Sagrado Coração (USC)instacron:USCORIGINALSintese, caracterizacao e potencial uso como agente antifungico de nanoparticulas de dioxido de titanio (227046).pdfSintese, caracterizacao e potencial uso como agente antifungico de nanoparticulas de dioxido de titanio (227046).pdfapplication/pdf4140236http://localhost:8080/tede/bitstream/tede/459/2/Sintese%2C+caracterizacao+e+potencial+uso+como+agente+antifungico+de+nanoparticulas+de+dioxido+de+titanio+%28227046%29.pdf36dbcaa6b2373a43232f8b0253f719acMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://localhost:8080/tede/bitstream/tede/459/1/license.txtbd3efa91386c1718a7f26a329fdcb468MD51tede/4592019-05-10 15:51:41.467oai:localhost: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Biblioteca Digital de Teses e Dissertaçõeshttps://tede2.usc.br:8443/http://tede2.usc.br:8080/oai/requestbiblicorjesu@unisagrado.edu.br||normalizacao@usc.bropendoar:2019-05-10T18:51:41Biblioteca Digital de Teses e Dissertações da USC - Universidade do Sagrado Coração (USC)false |
dc.title.eng.fl_str_mv |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
dc.title.alternative.eng.fl_str_mv |
Synthesis, characterization and potential use as antifungal agent of titanium dioxide nanoparticles |
title |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
spellingShingle |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio Michellotti, Michel Augusto Massambani Método Pechini Fotocatálise Aspergillus niger Antifúngico Pechini method Photocatalyst Aspergillus niger Antifungal CIENCIAS EXATAS E DA TERRA |
title_short |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
title_full |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
title_fullStr |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
title_full_unstemmed |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
title_sort |
Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio |
author |
Michellotti, Michel Augusto Massambani |
author_facet |
Michellotti, Michel Augusto Massambani |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Kinoshita, Angela Mitie Otta |
dc.contributor.advisor1ID.fl_str_mv |
10915343819 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/9357035017384643 |
dc.contributor.advisor-co1.fl_str_mv |
Chaves, Marcia Rodrigues De Morais |
dc.contributor.advisor-co1ID.fl_str_mv |
18088282837 |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/4623038987645528 |
dc.contributor.authorID.fl_str_mv |
44131325802 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/8907082465672671 |
dc.contributor.author.fl_str_mv |
Michellotti, Michel Augusto Massambani |
contributor_str_mv |
Kinoshita, Angela Mitie Otta Chaves, Marcia Rodrigues De Morais |
dc.subject.por.fl_str_mv |
Método Pechini Fotocatálise Aspergillus niger Antifúngico |
topic |
Método Pechini Fotocatálise Aspergillus niger Antifúngico Pechini method Photocatalyst Aspergillus niger Antifungal CIENCIAS EXATAS E DA TERRA |
dc.subject.eng.fl_str_mv |
Pechini method Photocatalyst Aspergillus niger Antifungal |
dc.subject.cnpq.fl_str_mv |
CIENCIAS EXATAS E DA TERRA |
description |
Titanium dioxide is extremely important because of its physical and chemical properties and different types of crystalline morphology (Anatase, Rutile and Broquita). It is currently used in the fields of science, environmental and energy. The nanoparticulate form has advantages or specificities, since this material achieves a more efficient relation between surface / volume, causing it to have a larger area of action mainly in the use of its photocatalytic properties. In this work the synthesis of the titanium dioxide nanoparticle was carried out using the Pechini method, varying the synthesis temperature in order to observe the changes in its morphology and physico-chemical properties. The nanoparticles (NPs) synthesized as well as the commercial titanium dioxide were characterized by X-ray diffraction (XRD) and morphologically by Scanning Electron Microscopy (SEM). Its ability to generate hydroxyl radicals was determined by Electron Spin Resonance (RSE). Since the Aspergillus niger fungus tends to develop in humid environments bringing harm to society and the environment, this work proposed the use of NPs as an antifungal agent. The antifungal activities of the materials were evaluated through the Minimum Inhibitory Concentration (MIC). The DRX showed that the obtained phase with a temperature of 400ºC is Anatase and presents a higher ratio surface / volume, the diameter of the smaller crystallite of 7.74nm, the other samples analyzed were crystallographically presented as Rutilo and its diameter of 34,89nm. The DLS of the TiO2A sample showed that the nanoparticles were in the diameter range of 60 to 120 nm. The experiments with RSE showed that this crystalline phase Anatase presents better photocatalytic characteristics than the other samples, since its relation surface / volume is bigger than the other samples. The CIM showed that Anatase sample obtained a more expressive result in the antifungal aspect where the concentration (750ug / ml) to eliminate the fungus was smaller than the other samples. |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-05-10T18:51:41Z |
dc.date.issued.fl_str_mv |
2019-02-18 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Michellotti, Michel Augusto Massambani. Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio. 2019. 36f. Dissertação (Mestrado em Ciência e Tecnologia Ambiental) - Universidade do Sagrado Coração, Bauru, 2019 . |
dc.identifier.uri.fl_str_mv |
https://tede2.usc.br:8443/handle/tede/459 |
identifier_str_mv |
Michellotti, Michel Augusto Massambani. Síntese, caracterização e potencial uso como agente antifúngico de nanopartículas de dióxido de titânio. 2019. 36f. Dissertação (Mestrado em Ciência e Tecnologia Ambiental) - Universidade do Sagrado Coração, Bauru, 2019 . |
url |
https://tede2.usc.br:8443/handle/tede/459 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
8879801746566820546 |
dc.relation.confidence.fl_str_mv |
600 600 600 600 |
dc.relation.department.fl_str_mv |
-753428887677182963 |
dc.relation.cnpq.fl_str_mv |
-4537326059604784016 |
dc.relation.sponsorship.fl_str_mv |
2075167498588264571 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade do Sagrado Coração |
dc.publisher.program.fl_str_mv |
Ciência e Tecnologia Ambiental |
dc.publisher.initials.fl_str_mv |
USC |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Ciências da Saúde e Biológicas |
publisher.none.fl_str_mv |
Universidade do Sagrado Coração |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações da USC instname:Universidade do Sagrado Coração (USC) instacron:USC |
instname_str |
Universidade do Sagrado Coração (USC) |
instacron_str |
USC |
institution |
USC |
reponame_str |
Biblioteca Digital de Teses e Dissertações da USC |
collection |
Biblioteca Digital de Teses e Dissertações da USC |
bitstream.url.fl_str_mv |
http://localhost:8080/tede/bitstream/tede/459/2/Sintese%2C+caracterizacao+e+potencial+uso+como+agente+antifungico+de+nanoparticulas+de+dioxido+de+titanio+%28227046%29.pdf http://localhost:8080/tede/bitstream/tede/459/1/license.txt |
bitstream.checksum.fl_str_mv |
36dbcaa6b2373a43232f8b0253f719ac bd3efa91386c1718a7f26a329fdcb468 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações da USC - Universidade do Sagrado Coração (USC) |
repository.mail.fl_str_mv |
biblicorjesu@unisagrado.edu.br||normalizacao@usc.br |
_version_ |
1800410547879936000 |