Comparative study of rules employed for calculation of pediatric drug dosage

Detalhes bibliográficos
Autor(a) principal: Elias, Gracieli Prado
Data de Publicação: 2005
Outros Autores: Antoniali, Cristina, Mariano, Ronaldo Célio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3260
Resumo: The present study was conducted to evaluate the utilization of Clark's, Salisbury and Penna's rules and the Body Surface Area (BSA) formula for calculation of pediatric drug dosage, as well as their reliability and viability in the clinical use. These rules are frequently cited in the literature, but much controversy still exists with regards to their use. The pediatric drug dosage was calculated by utilization of the aforementioned rules and using the drugs Paracetamol, Dipyrone, Diclofenac Potassium, Nimesulide, Amoxicillin and Erythromycin, widely employed in Pediatric Dentistry. Weight and body surface areas were considered of children with ages between 1 and 12 years old as well as the dosage for the adult. The pediatric dosages achieved were compared to the predetermined dosages in mg kg-1 herein-named standard dosages. The results were submitted to the parametric test ANOVA and to the Tukey test (p
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spelling Comparative study of rules employed for calculation of pediatric drug dosage Estudo comparativo de fórmulas empregadas no cálculo de doses medicamentosas infantis OdontopediatriaAdministração oral de medicamentosposologiaPediatric dentistryOral administrationposology The present study was conducted to evaluate the utilization of Clark's, Salisbury and Penna's rules and the Body Surface Area (BSA) formula for calculation of pediatric drug dosage, as well as their reliability and viability in the clinical use. These rules are frequently cited in the literature, but much controversy still exists with regards to their use. The pediatric drug dosage was calculated by utilization of the aforementioned rules and using the drugs Paracetamol, Dipyrone, Diclofenac Potassium, Nimesulide, Amoxicillin and Erythromycin, widely employed in Pediatric Dentistry. Weight and body surface areas were considered of children with ages between 1 and 12 years old as well as the dosage for the adult. The pediatric dosages achieved were compared to the predetermined dosages in mg kg-1 herein-named standard dosages. The results were submitted to the parametric test ANOVA and to the Tukey test (p O presente estudo foi realizado com a finalidade de avaliar as fórmulas de Clark, Salisbury, Área da Superfície Corpórea (ASC) e Penna, quanto a sua confiabilidade e viabilidade de uso clínico para o cálculo de doses medicamentosas infantis, uma vez que tais fórmulas são freqüentemente citadas na literatura, mas muita controvérsia ainda existe com relação ao seu uso. As doses infantis foram calculadas utilizando as fórmulas descritas e os medicamentos Paracetamol, Dipirona, Diclofenaco de Potássio, Nimesulida, Amoxicilina e Eritromicina, largamente usados na clínica odontopediátrica. Foram considerados parâmetros como o peso e área da superfície corpórea de crianças com idades entre 1 e 12 anos e a dose para o adulto. As doses obtidas foram comparadas às doses em mg/kg consideradas como padrão de referência para os medicamentos. Os resultados foram submetidos ao teste paramétrico ANOVA e de Tukey (PUniversidade de São Paulo. Faculdade de Odontologia de Bauru2005-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/326010.1590/S1678-77572005000200004Journal of Applied Oral Science; Vol. 13 No. 2 (2005); 114-119 Journal of Applied Oral Science; Vol. 13 Núm. 2 (2005); 114-119 Journal of Applied Oral Science; v. 13 n. 2 (2005); 114-119 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3260/3950Copyright (c) 2005 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessElias, Gracieli PradoAntoniali, CristinaMariano, Ronaldo Célio2012-04-27T11:50:02Zoai:revistas.usp.br:article/3260Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T11:50:02Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Comparative study of rules employed for calculation of pediatric drug dosage
Estudo comparativo de fórmulas empregadas no cálculo de doses medicamentosas infantis
title Comparative study of rules employed for calculation of pediatric drug dosage
spellingShingle Comparative study of rules employed for calculation of pediatric drug dosage
Elias, Gracieli Prado
Odontopediatria
Administração oral de medicamentos
posologia
Pediatric dentistry
Oral administration
posology
title_short Comparative study of rules employed for calculation of pediatric drug dosage
title_full Comparative study of rules employed for calculation of pediatric drug dosage
title_fullStr Comparative study of rules employed for calculation of pediatric drug dosage
title_full_unstemmed Comparative study of rules employed for calculation of pediatric drug dosage
title_sort Comparative study of rules employed for calculation of pediatric drug dosage
author Elias, Gracieli Prado
author_facet Elias, Gracieli Prado
Antoniali, Cristina
Mariano, Ronaldo Célio
author_role author
author2 Antoniali, Cristina
Mariano, Ronaldo Célio
author2_role author
author
dc.contributor.author.fl_str_mv Elias, Gracieli Prado
Antoniali, Cristina
Mariano, Ronaldo Célio
dc.subject.por.fl_str_mv Odontopediatria
Administração oral de medicamentos
posologia
Pediatric dentistry
Oral administration
posology
topic Odontopediatria
Administração oral de medicamentos
posologia
Pediatric dentistry
Oral administration
posology
description The present study was conducted to evaluate the utilization of Clark's, Salisbury and Penna's rules and the Body Surface Area (BSA) formula for calculation of pediatric drug dosage, as well as their reliability and viability in the clinical use. These rules are frequently cited in the literature, but much controversy still exists with regards to their use. The pediatric drug dosage was calculated by utilization of the aforementioned rules and using the drugs Paracetamol, Dipyrone, Diclofenac Potassium, Nimesulide, Amoxicillin and Erythromycin, widely employed in Pediatric Dentistry. Weight and body surface areas were considered of children with ages between 1 and 12 years old as well as the dosage for the adult. The pediatric dosages achieved were compared to the predetermined dosages in mg kg-1 herein-named standard dosages. The results were submitted to the parametric test ANOVA and to the Tukey test (p
publishDate 2005
dc.date.none.fl_str_mv 2005-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3260
10.1590/S1678-77572005000200004
url https://www.revistas.usp.br/jaos/article/view/3260
identifier_str_mv 10.1590/S1678-77572005000200004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3260/3950
dc.rights.driver.fl_str_mv Copyright (c) 2005 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2005 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 13 No. 2 (2005); 114-119
Journal of Applied Oral Science; Vol. 13 Núm. 2 (2005); 114-119
Journal of Applied Oral Science; v. 13 n. 2 (2005); 114-119
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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