Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats
Autor(a) principal: | |
---|---|
Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000500011 |
Resumo: | OBJECTIVE: This study evaluated experimentally-induced periapical bone loss sites using digital radiographic and histopathologic parameters. MATERIAL AND METHODS: Twenty-seven Wistar rats were submitted to coronal opening of their mandibular right first molars. They were radiographed at 2, 15 and 30 days after the operative procedure by two digital radiographic storage phosphor plates (Digora®). The images were analyzed by creating a region of interest at the periapical region of each tooth (ImageJ) and registering the corresponding pixel values. After the sacrifice, the specimens were submitted to microscopic analysis in order to confirm the pulpal and periapical status of the tooth. RESULTS: There was significant statistically difference between the control and test sides in all the experimental periods regarding the pixel values (two-way ANOVA; p<0.05). CONCLUSIONS: The microscopic analysis proved that a periapical disease development occurred during the experimental periods with an evolution from pulpal necrosis to periapical bone resorption. |
id |
USP-17_19fe08ab032106b5e7e93cceed089303 |
---|---|
oai_identifier_str |
oai:scielo:S1678-77572011000500011 |
network_acronym_str |
USP-17 |
network_name_str |
Journal of applied oral science (Online) |
repository_id_str |
|
spelling |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in ratsRadiologyPeriapical diseasesHistologyRatsOBJECTIVE: This study evaluated experimentally-induced periapical bone loss sites using digital radiographic and histopathologic parameters. MATERIAL AND METHODS: Twenty-seven Wistar rats were submitted to coronal opening of their mandibular right first molars. They were radiographed at 2, 15 and 30 days after the operative procedure by two digital radiographic storage phosphor plates (Digora®). The images were analyzed by creating a region of interest at the periapical region of each tooth (ImageJ) and registering the corresponding pixel values. After the sacrifice, the specimens were submitted to microscopic analysis in order to confirm the pulpal and periapical status of the tooth. RESULTS: There was significant statistically difference between the control and test sides in all the experimental periods regarding the pixel values (two-way ANOVA; p<0.05). CONCLUSIONS: The microscopic analysis proved that a periapical disease development occurred during the experimental periods with an evolution from pulpal necrosis to periapical bone resorption.Faculdade De Odontologia De Bauru - USP2011-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000500011Journal of Applied Oral Science v.19 n.5 2011reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/S1678-77572011005000020info:eu-repo/semantics/openAccessTeixeira,Renata CordeiroRubira,Cassia Maria FischerAssis,Gerson FranciscoLauris,José Roberto PereiraCestari,Tania MaryRubira-Bullen,Izabel Regina Fischereng2011-09-29T00:00:00Zoai:scielo:S1678-77572011000500011Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2011-09-29T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
title |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
spellingShingle |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats Teixeira,Renata Cordeiro Radiology Periapical diseases Histology Rats |
title_short |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
title_full |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
title_fullStr |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
title_full_unstemmed |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
title_sort |
Radiological and histopathological evaluation of experimentally-induced periapical lesion in rats |
author |
Teixeira,Renata Cordeiro |
author_facet |
Teixeira,Renata Cordeiro Rubira,Cassia Maria Fischer Assis,Gerson Francisco Lauris,José Roberto Pereira Cestari,Tania Mary Rubira-Bullen,Izabel Regina Fischer |
author_role |
author |
author2 |
Rubira,Cassia Maria Fischer Assis,Gerson Francisco Lauris,José Roberto Pereira Cestari,Tania Mary Rubira-Bullen,Izabel Regina Fischer |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Teixeira,Renata Cordeiro Rubira,Cassia Maria Fischer Assis,Gerson Francisco Lauris,José Roberto Pereira Cestari,Tania Mary Rubira-Bullen,Izabel Regina Fischer |
dc.subject.por.fl_str_mv |
Radiology Periapical diseases Histology Rats |
topic |
Radiology Periapical diseases Histology Rats |
description |
OBJECTIVE: This study evaluated experimentally-induced periapical bone loss sites using digital radiographic and histopathologic parameters. MATERIAL AND METHODS: Twenty-seven Wistar rats were submitted to coronal opening of their mandibular right first molars. They were radiographed at 2, 15 and 30 days after the operative procedure by two digital radiographic storage phosphor plates (Digora®). The images were analyzed by creating a region of interest at the periapical region of each tooth (ImageJ) and registering the corresponding pixel values. After the sacrifice, the specimens were submitted to microscopic analysis in order to confirm the pulpal and periapical status of the tooth. RESULTS: There was significant statistically difference between the control and test sides in all the experimental periods regarding the pixel values (two-way ANOVA; p<0.05). CONCLUSIONS: The microscopic analysis proved that a periapical disease development occurred during the experimental periods with an evolution from pulpal necrosis to periapical bone resorption. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000500011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000500011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1678-77572011005000020 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade De Odontologia De Bauru - USP |
publisher.none.fl_str_mv |
Faculdade De Odontologia De Bauru - USP |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science v.19 n.5 2011 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1748936437071347712 |