Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/200538 |
Resumo: | Objectives: This study aimed to compare two different soft tissue replacement grafts in their ability to treat gingival recession defects and successfully integrate with the surrounding tissues. Methodology: Nine beagle dogs were included and followed up to 10 weeks. Sites for intervention were allocated to one of the grafting materials investigated. Treatment consisted of coronally advanced flap combined with one of the two soft tissue substitutes on a previous surgically created defect. Materials employed were porcine-derived acellular dermal matrix (ADM) [Novomatrix™ (Test)] and collagen-based matrix (CBM) [Mucograft® (Control)]. Animals were sacrificed at 2, 6, and 10 weeks postoperatively and compared using descriptive histology and histomorphometric outcomes. Results: Macroscopic findings were similar between test and control groups at all intervals. After 10 weeks, both groups demonstrated successful incorporation of the grafting materials without signs of rejection and with comparable tissue integration. The histomorphometric data were similar between groups at 2 weeks; however, the test group provided greater root coverage and increase in tissue thickness than the control at 6- and 10-weeks post surgically. Conclusions: Both porcine-derived ADM and CBM revealed similar histological outcomes with successful integration and absence of adverse events. Test group provided superior outcomes regarding root coverage and increase in tissue thickness. |
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Journal of applied oral science (Online) |
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Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological studyGingival recessionEsthetics; DentalSurgeryPlasticTreatment outcomeObjectives: This study aimed to compare two different soft tissue replacement grafts in their ability to treat gingival recession defects and successfully integrate with the surrounding tissues. Methodology: Nine beagle dogs were included and followed up to 10 weeks. Sites for intervention were allocated to one of the grafting materials investigated. Treatment consisted of coronally advanced flap combined with one of the two soft tissue substitutes on a previous surgically created defect. Materials employed were porcine-derived acellular dermal matrix (ADM) [Novomatrix™ (Test)] and collagen-based matrix (CBM) [Mucograft® (Control)]. Animals were sacrificed at 2, 6, and 10 weeks postoperatively and compared using descriptive histology and histomorphometric outcomes. Results: Macroscopic findings were similar between test and control groups at all intervals. After 10 weeks, both groups demonstrated successful incorporation of the grafting materials without signs of rejection and with comparable tissue integration. The histomorphometric data were similar between groups at 2 weeks; however, the test group provided greater root coverage and increase in tissue thickness than the control at 6- and 10-weeks post surgically. Conclusions: Both porcine-derived ADM and CBM revealed similar histological outcomes with successful integration and absence of adverse events. Test group provided superior outcomes regarding root coverage and increase in tissue thickness.Universidade de São Paulo. Faculdade de Odontologia de Bauru2022-07-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/20053810.1590/1678-7757-2018-0584Journal of Applied Oral Science; Vol. 27 (2019); e20180584Journal of Applied Oral Science; Vol. 27 (2019); e20180584Journal of Applied Oral Science; v. 27 (2019); e201805841678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/200538/184750Copyright (c) 2022 Journal of Applied Oral Sciencehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDel Amo, Fernando Suárez-López Rodriguez, Juan C. Asa'ad, Farah Wang, Hom-Lay 2022-07-29T13:57:51Zoai:revistas.usp.br:article/200538Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2022-07-29T13:57:51Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
title |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
spellingShingle |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study Del Amo, Fernando Suárez-López Gingival recession Esthetics; Dental Surgery Plastic Treatment outcome |
title_short |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
title_full |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
title_fullStr |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
title_full_unstemmed |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
title_sort |
Comparison of two soft tissue substitutes for the treatment of gingival recession defects: an animal histological study |
author |
Del Amo, Fernando Suárez-López |
author_facet |
Del Amo, Fernando Suárez-López Rodriguez, Juan C. Asa'ad, Farah Wang, Hom-Lay |
author_role |
author |
author2 |
Rodriguez, Juan C. Asa'ad, Farah Wang, Hom-Lay |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Del Amo, Fernando Suárez-López Rodriguez, Juan C. Asa'ad, Farah Wang, Hom-Lay |
dc.subject.por.fl_str_mv |
Gingival recession Esthetics; Dental Surgery Plastic Treatment outcome |
topic |
Gingival recession Esthetics; Dental Surgery Plastic Treatment outcome |
description |
Objectives: This study aimed to compare two different soft tissue replacement grafts in their ability to treat gingival recession defects and successfully integrate with the surrounding tissues. Methodology: Nine beagle dogs were included and followed up to 10 weeks. Sites for intervention were allocated to one of the grafting materials investigated. Treatment consisted of coronally advanced flap combined with one of the two soft tissue substitutes on a previous surgically created defect. Materials employed were porcine-derived acellular dermal matrix (ADM) [Novomatrix™ (Test)] and collagen-based matrix (CBM) [Mucograft® (Control)]. Animals were sacrificed at 2, 6, and 10 weeks postoperatively and compared using descriptive histology and histomorphometric outcomes. Results: Macroscopic findings were similar between test and control groups at all intervals. After 10 weeks, both groups demonstrated successful incorporation of the grafting materials without signs of rejection and with comparable tissue integration. The histomorphometric data were similar between groups at 2 weeks; however, the test group provided greater root coverage and increase in tissue thickness than the control at 6- and 10-weeks post surgically. Conclusions: Both porcine-derived ADM and CBM revealed similar histological outcomes with successful integration and absence of adverse events. Test group provided superior outcomes regarding root coverage and increase in tissue thickness. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/200538 10.1590/1678-7757-2018-0584 |
url |
https://www.revistas.usp.br/jaos/article/view/200538 |
identifier_str_mv |
10.1590/1678-7757-2018-0584 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/200538/184750 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 27 (2019); e20180584 Journal of Applied Oral Science; Vol. 27 (2019); e20180584 Journal of Applied Oral Science; v. 27 (2019); e20180584 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221682663686144 |