Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study

Detalhes bibliográficos
Autor(a) principal: Ghizoni, Janaina Salomon
Data de Publicação: 2012
Outros Autores: Taveira, Luís Antônio de Assis, Garlet, Gustavo Pompermaier, Ghizoni, Marcos Flávio, Pereira, Jefferson Ricardo, Dionísio, Thiago José, Brozoski, Daniel Thomas, Santos, Carlos Ferreira, Sant'Ana, Adriana Campos Passanezi
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3994
Resumo: OBJECTIVE: This study investigated the role of periodontal disease in the development of stroke or cerebral infarction in patients by evaluating the clinical periodontal conditions and the subgingival levels of periodontopathogens. MATERIAL AND METHODS: Twenty patients with ischemic (I-CVA) or hemorrhagic (H-CVA) cerebrovascular episodes (test group) and 60 systemically healthy patients (control group) were evaluated for: probing depth, clinical attachment level, bleeding on probing and plaque index. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans were both identified and quantified in subgingival plaque samples by conventional and real-time PCR, respectively. RESULTS: The test group showed a significant increase in each of the following parameters: pocket depth, clinical attachment loss, bleeding on probing, plaque index and number of missing teeth when compared to control values (p
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spelling Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study Periodontal diseasesStrokeInfectionPathogenesisAtherogenesis OBJECTIVE: This study investigated the role of periodontal disease in the development of stroke or cerebral infarction in patients by evaluating the clinical periodontal conditions and the subgingival levels of periodontopathogens. MATERIAL AND METHODS: Twenty patients with ischemic (I-CVA) or hemorrhagic (H-CVA) cerebrovascular episodes (test group) and 60 systemically healthy patients (control group) were evaluated for: probing depth, clinical attachment level, bleeding on probing and plaque index. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans were both identified and quantified in subgingival plaque samples by conventional and real-time PCR, respectively. RESULTS: The test group showed a significant increase in each of the following parameters: pocket depth, clinical attachment loss, bleeding on probing, plaque index and number of missing teeth when compared to control values (pUniversidade de São Paulo. Faculdade de Odontologia de Bauru2012-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/399410.1590/S1678-77572012000100019Journal of Applied Oral Science; Vol. 20 No. 1 (2012); 104-112 Journal of Applied Oral Science; Vol. 20 Núm. 1 (2012); 104-112 Journal of Applied Oral Science; v. 20 n. 1 (2012); 104-112 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3994/4684Copyright (c) 2012 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessGhizoni, Janaina SalomonTaveira, Luís Antônio de AssisGarlet, Gustavo PompermaierGhizoni, Marcos FlávioPereira, Jefferson RicardoDionísio, Thiago JoséBrozoski, Daniel ThomasSantos, Carlos FerreiraSant'Ana, Adriana Campos Passanezi2012-04-27T12:17:57Zoai:revistas.usp.br:article/3994Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:17:57Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
title Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
spellingShingle Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
Ghizoni, Janaina Salomon
Periodontal diseases
Stroke
Infection
Pathogenesis
Atherogenesis
title_short Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
title_full Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
title_fullStr Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
title_full_unstemmed Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
title_sort Increased levels of Porphyromonas gingivalis are associated with ischemic and hemorrhagic cerebrovascular disease in humans: an in vivo study
author Ghizoni, Janaina Salomon
author_facet Ghizoni, Janaina Salomon
Taveira, Luís Antônio de Assis
Garlet, Gustavo Pompermaier
Ghizoni, Marcos Flávio
Pereira, Jefferson Ricardo
Dionísio, Thiago José
Brozoski, Daniel Thomas
Santos, Carlos Ferreira
Sant'Ana, Adriana Campos Passanezi
author_role author
author2 Taveira, Luís Antônio de Assis
Garlet, Gustavo Pompermaier
Ghizoni, Marcos Flávio
Pereira, Jefferson Ricardo
Dionísio, Thiago José
Brozoski, Daniel Thomas
Santos, Carlos Ferreira
Sant'Ana, Adriana Campos Passanezi
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Ghizoni, Janaina Salomon
Taveira, Luís Antônio de Assis
Garlet, Gustavo Pompermaier
Ghizoni, Marcos Flávio
Pereira, Jefferson Ricardo
Dionísio, Thiago José
Brozoski, Daniel Thomas
Santos, Carlos Ferreira
Sant'Ana, Adriana Campos Passanezi
dc.subject.por.fl_str_mv Periodontal diseases
Stroke
Infection
Pathogenesis
Atherogenesis
topic Periodontal diseases
Stroke
Infection
Pathogenesis
Atherogenesis
description OBJECTIVE: This study investigated the role of periodontal disease in the development of stroke or cerebral infarction in patients by evaluating the clinical periodontal conditions and the subgingival levels of periodontopathogens. MATERIAL AND METHODS: Twenty patients with ischemic (I-CVA) or hemorrhagic (H-CVA) cerebrovascular episodes (test group) and 60 systemically healthy patients (control group) were evaluated for: probing depth, clinical attachment level, bleeding on probing and plaque index. Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans were both identified and quantified in subgingival plaque samples by conventional and real-time PCR, respectively. RESULTS: The test group showed a significant increase in each of the following parameters: pocket depth, clinical attachment loss, bleeding on probing, plaque index and number of missing teeth when compared to control values (p
publishDate 2012
dc.date.none.fl_str_mv 2012-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3994
10.1590/S1678-77572012000100019
url https://www.revistas.usp.br/jaos/article/view/3994
identifier_str_mv 10.1590/S1678-77572012000100019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3994/4684
dc.rights.driver.fl_str_mv Copyright (c) 2012 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2012 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 20 No. 1 (2012); 104-112
Journal of Applied Oral Science; Vol. 20 Núm. 1 (2012); 104-112
Journal of Applied Oral Science; v. 20 n. 1 (2012); 104-112
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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