Two mechanisms of oral malodor inhibition by zinc ions
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/142443 |
Resumo: | Objectives The aim of this study was to reveal the mechanisms by which zinc ions inhibit oral malodor. Material and Methods The direct binding of zinc ions to gaseous hydrogen sulfide (H2S) was assessed in comparison with other metal ions. Nine metal chlorides and six metal acetates were examined. To understand the strength of H2S volatilization inhibition, the minimum concentration needed to inhibit H2S volatilization was determined using serial dilution methods. Subsequently, the inhibitory activities of zinc ions on the growth of six oral bacterial strains related to volatile sulfur compound (VSC) production and three strains not related to VSC production were evaluated. Results Aqueous solutions of ZnCl2, CdCl2, CuCl2, (CH3COO)2Zn, (CH3COO)2Cd, (CH3COO)2Cu, and CH3COOAg inhibited H2S volatilization almost entirely. The strengths of H2S volatilization inhibition were in the order Ag+ >; Cd2+ >; Cu2+ >; Zn2+. The effect of zinc ions on the growth of oral bacteria was strain-dependent. Fusobacterium nucleatum ATCC 25586 was the most sensitive, as it was suppressed by medium containing 0.001% zinc ions. Conclusions Zinc ions have an inhibitory effect on oral malodor involving the two mechanisms of direct binding with gaseous H2S and suppressing the growth of VSC-producing oral bacteria. |
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Journal of applied oral science (Online) |
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Two mechanisms of oral malodor inhibition by zinc ionsAntimicrobial activityChemical bindingHydrogen sulfideOral malodorZinc ions Objectives The aim of this study was to reveal the mechanisms by which zinc ions inhibit oral malodor. Material and Methods The direct binding of zinc ions to gaseous hydrogen sulfide (H2S) was assessed in comparison with other metal ions. Nine metal chlorides and six metal acetates were examined. To understand the strength of H2S volatilization inhibition, the minimum concentration needed to inhibit H2S volatilization was determined using serial dilution methods. Subsequently, the inhibitory activities of zinc ions on the growth of six oral bacterial strains related to volatile sulfur compound (VSC) production and three strains not related to VSC production were evaluated. Results Aqueous solutions of ZnCl2, CdCl2, CuCl2, (CH3COO)2Zn, (CH3COO)2Cd, (CH3COO)2Cu, and CH3COOAg inhibited H2S volatilization almost entirely. The strengths of H2S volatilization inhibition were in the order Ag+ >; Cd2+ >; Cu2+ >; Zn2+. The effect of zinc ions on the growth of oral bacteria was strain-dependent. Fusobacterium nucleatum ATCC 25586 was the most sensitive, as it was suppressed by medium containing 0.001% zinc ions. Conclusions Zinc ions have an inhibitory effect on oral malodor involving the two mechanisms of direct binding with gaseous H2S and suppressing the growth of VSC-producing oral bacteria.Universidade de São Paulo. Faculdade de Odontologia de Bauru2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/14244310.1590/1678-7757-2017-0161Journal of Applied Oral Science; Vol. 26 (2018); e20170161Journal of Applied Oral Science; Vol. 26 (2018); e20170161Journal of Applied Oral Science; v. 26 (2018); e201701611678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/142443/137552Copyright (c) 2018 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessSuzuki, NaoNakano, YoshioWatanabe, TakeshiYoneda, MasahiroHirofuji, TakaoHanioka, Takashi2018-03-20T12:30:06Zoai:revistas.usp.br:article/142443Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2018-03-20T12:30:06Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Two mechanisms of oral malodor inhibition by zinc ions |
title |
Two mechanisms of oral malodor inhibition by zinc ions |
spellingShingle |
Two mechanisms of oral malodor inhibition by zinc ions Suzuki, Nao Antimicrobial activity Chemical binding Hydrogen sulfide Oral malodor Zinc ions |
title_short |
Two mechanisms of oral malodor inhibition by zinc ions |
title_full |
Two mechanisms of oral malodor inhibition by zinc ions |
title_fullStr |
Two mechanisms of oral malodor inhibition by zinc ions |
title_full_unstemmed |
Two mechanisms of oral malodor inhibition by zinc ions |
title_sort |
Two mechanisms of oral malodor inhibition by zinc ions |
author |
Suzuki, Nao |
author_facet |
Suzuki, Nao Nakano, Yoshio Watanabe, Takeshi Yoneda, Masahiro Hirofuji, Takao Hanioka, Takashi |
author_role |
author |
author2 |
Nakano, Yoshio Watanabe, Takeshi Yoneda, Masahiro Hirofuji, Takao Hanioka, Takashi |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Suzuki, Nao Nakano, Yoshio Watanabe, Takeshi Yoneda, Masahiro Hirofuji, Takao Hanioka, Takashi |
dc.subject.por.fl_str_mv |
Antimicrobial activity Chemical binding Hydrogen sulfide Oral malodor Zinc ions |
topic |
Antimicrobial activity Chemical binding Hydrogen sulfide Oral malodor Zinc ions |
description |
Objectives The aim of this study was to reveal the mechanisms by which zinc ions inhibit oral malodor. Material and Methods The direct binding of zinc ions to gaseous hydrogen sulfide (H2S) was assessed in comparison with other metal ions. Nine metal chlorides and six metal acetates were examined. To understand the strength of H2S volatilization inhibition, the minimum concentration needed to inhibit H2S volatilization was determined using serial dilution methods. Subsequently, the inhibitory activities of zinc ions on the growth of six oral bacterial strains related to volatile sulfur compound (VSC) production and three strains not related to VSC production were evaluated. Results Aqueous solutions of ZnCl2, CdCl2, CuCl2, (CH3COO)2Zn, (CH3COO)2Cd, (CH3COO)2Cu, and CH3COOAg inhibited H2S volatilization almost entirely. The strengths of H2S volatilization inhibition were in the order Ag+ >; Cd2+ >; Cu2+ >; Zn2+. The effect of zinc ions on the growth of oral bacteria was strain-dependent. Fusobacterium nucleatum ATCC 25586 was the most sensitive, as it was suppressed by medium containing 0.001% zinc ions. Conclusions Zinc ions have an inhibitory effect on oral malodor involving the two mechanisms of direct binding with gaseous H2S and suppressing the growth of VSC-producing oral bacteria. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/142443 10.1590/1678-7757-2017-0161 |
url |
https://www.revistas.usp.br/jaos/article/view/142443 |
identifier_str_mv |
10.1590/1678-7757-2017-0161 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/142443/137552 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2018 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2018 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 26 (2018); e20170161 Journal of Applied Oral Science; Vol. 26 (2018); e20170161 Journal of Applied Oral Science; v. 26 (2018); e20170161 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221680491036672 |