Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012 |
Resumo: | OBJECTIVE: This study investigated the pulpal effect of topically applied betamethasone to the dentin of rat molars in the vascular phase of inflammation. MATERIAL AND METHODS: Deep cavities were prepared on the occlusal face of the maxillary right and left 1st molars with non-refrigerated inverted-cone steel burs at low speed. Three groups were formed: Group I was composed of right 1st molars; Group II was composed of left 1st molars that received the application of a drop of betamethasone on dentin surface for 5 min; and Group III (control) was composed of right 2nd molars that received no cavity preparation or betamethasone application. Changes in the vascular characteristics of the pulp tissue were checked by calculating the pulp vascular area in relation to its total area and the number of blood vessels per unit area. Data were subjected to ANOVA and Tukey's test (?=0.05). RESULTS: Group I presented a significantly larger number of vessels (p<0.05) than Group II. Regarding the vascular/total area ratio (%), Group I presented statistically significantly higher values (p=0.01) than Groups II and III. CONCLUSION: Betamethasone applied on the dentin of rat teeth proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels. |
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Journal of applied oral science (Online) |
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Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammationInflammationDental pulpBetamethasoneOBJECTIVE: This study investigated the pulpal effect of topically applied betamethasone to the dentin of rat molars in the vascular phase of inflammation. MATERIAL AND METHODS: Deep cavities were prepared on the occlusal face of the maxillary right and left 1st molars with non-refrigerated inverted-cone steel burs at low speed. Three groups were formed: Group I was composed of right 1st molars; Group II was composed of left 1st molars that received the application of a drop of betamethasone on dentin surface for 5 min; and Group III (control) was composed of right 2nd molars that received no cavity preparation or betamethasone application. Changes in the vascular characteristics of the pulp tissue were checked by calculating the pulp vascular area in relation to its total area and the number of blood vessels per unit area. Data were subjected to ANOVA and Tukey's test (?=0.05). RESULTS: Group I presented a significantly larger number of vessels (p<0.05) than Group II. Regarding the vascular/total area ratio (%), Group I presented statistically significantly higher values (p=0.01) than Groups II and III. CONCLUSION: Betamethasone applied on the dentin of rat teeth proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels.Faculdade De Odontologia De Bauru - USP2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012Journal of Applied Oral Science v.17 n.4 2009reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/S1678-77572009000400012info:eu-repo/semantics/openAccessFachin,Elaine Vianna FreitasScarparo,Roberta KochenborgerPezzi,Ana Paula WeissheimerLuisi,Simone BonatoSant'ana Filho,Manoeleng2009-07-31T00:00:00Zoai:scielo:S1678-77572009000400012Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2009-07-31T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
title |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
spellingShingle |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation Fachin,Elaine Vianna Freitas Inflammation Dental pulp Betamethasone |
title_short |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
title_full |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
title_fullStr |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
title_full_unstemmed |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
title_sort |
Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation |
author |
Fachin,Elaine Vianna Freitas |
author_facet |
Fachin,Elaine Vianna Freitas Scarparo,Roberta Kochenborger Pezzi,Ana Paula Weissheimer Luisi,Simone Bonato Sant'ana Filho,Manoel |
author_role |
author |
author2 |
Scarparo,Roberta Kochenborger Pezzi,Ana Paula Weissheimer Luisi,Simone Bonato Sant'ana Filho,Manoel |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Fachin,Elaine Vianna Freitas Scarparo,Roberta Kochenborger Pezzi,Ana Paula Weissheimer Luisi,Simone Bonato Sant'ana Filho,Manoel |
dc.subject.por.fl_str_mv |
Inflammation Dental pulp Betamethasone |
topic |
Inflammation Dental pulp Betamethasone |
description |
OBJECTIVE: This study investigated the pulpal effect of topically applied betamethasone to the dentin of rat molars in the vascular phase of inflammation. MATERIAL AND METHODS: Deep cavities were prepared on the occlusal face of the maxillary right and left 1st molars with non-refrigerated inverted-cone steel burs at low speed. Three groups were formed: Group I was composed of right 1st molars; Group II was composed of left 1st molars that received the application of a drop of betamethasone on dentin surface for 5 min; and Group III (control) was composed of right 2nd molars that received no cavity preparation or betamethasone application. Changes in the vascular characteristics of the pulp tissue were checked by calculating the pulp vascular area in relation to its total area and the number of blood vessels per unit area. Data were subjected to ANOVA and Tukey's test (?=0.05). RESULTS: Group I presented a significantly larger number of vessels (p<0.05) than Group II. Regarding the vascular/total area ratio (%), Group I presented statistically significantly higher values (p=0.01) than Groups II and III. CONCLUSION: Betamethasone applied on the dentin of rat teeth proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1678-77572009000400012 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade De Odontologia De Bauru - USP |
publisher.none.fl_str_mv |
Faculdade De Odontologia De Bauru - USP |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science v.17 n.4 2009 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1748936435596001280 |