Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation

Detalhes bibliográficos
Autor(a) principal: Fachin,Elaine Vianna Freitas
Data de Publicação: 2009
Outros Autores: Scarparo,Roberta Kochenborger, Pezzi,Ana Paula Weissheimer, Luisi,Simone Bonato, Sant'ana Filho,Manoel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012
Resumo: OBJECTIVE: This study investigated the pulpal effect of topically applied betamethasone to the dentin of rat molars in the vascular phase of inflammation. MATERIAL AND METHODS: Deep cavities were prepared on the occlusal face of the maxillary right and left 1st molars with non-refrigerated inverted-cone steel burs at low speed. Three groups were formed: Group I was composed of right 1st molars; Group II was composed of left 1st molars that received the application of a drop of betamethasone on dentin surface for 5 min; and Group III (control) was composed of right 2nd molars that received no cavity preparation or betamethasone application. Changes in the vascular characteristics of the pulp tissue were checked by calculating the pulp vascular area in relation to its total area and the number of blood vessels per unit area. Data were subjected to ANOVA and Tukey's test (?=0.05). RESULTS: Group I presented a significantly larger number of vessels (p<0.05) than Group II. Regarding the vascular/total area ratio (%), Group I presented statistically significantly higher values (p=0.01) than Groups II and III. CONCLUSION: Betamethasone applied on the dentin of rat teeth proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels.
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spelling Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammationInflammationDental pulpBetamethasoneOBJECTIVE: This study investigated the pulpal effect of topically applied betamethasone to the dentin of rat molars in the vascular phase of inflammation. MATERIAL AND METHODS: Deep cavities were prepared on the occlusal face of the maxillary right and left 1st molars with non-refrigerated inverted-cone steel burs at low speed. Three groups were formed: Group I was composed of right 1st molars; Group II was composed of left 1st molars that received the application of a drop of betamethasone on dentin surface for 5 min; and Group III (control) was composed of right 2nd molars that received no cavity preparation or betamethasone application. Changes in the vascular characteristics of the pulp tissue were checked by calculating the pulp vascular area in relation to its total area and the number of blood vessels per unit area. Data were subjected to ANOVA and Tukey's test (?=0.05). RESULTS: Group I presented a significantly larger number of vessels (p<0.05) than Group II. Regarding the vascular/total area ratio (%), Group I presented statistically significantly higher values (p=0.01) than Groups II and III. CONCLUSION: Betamethasone applied on the dentin of rat teeth proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels.Faculdade De Odontologia De Bauru - USP2009-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012Journal of Applied Oral Science v.17 n.4 2009reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/S1678-77572009000400012info:eu-repo/semantics/openAccessFachin,Elaine Vianna FreitasScarparo,Roberta KochenborgerPezzi,Ana Paula WeissheimerLuisi,Simone BonatoSant'ana Filho,Manoeleng2009-07-31T00:00:00Zoai:scielo:S1678-77572009000400012Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2009-07-31T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
title Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
spellingShingle Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
Fachin,Elaine Vianna Freitas
Inflammation
Dental pulp
Betamethasone
title_short Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
title_full Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
title_fullStr Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
title_full_unstemmed Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
title_sort Effect of betamethasone on the pulp after topical application to the dentin of rat teeth: vascular aspects of the inflammation
author Fachin,Elaine Vianna Freitas
author_facet Fachin,Elaine Vianna Freitas
Scarparo,Roberta Kochenborger
Pezzi,Ana Paula Weissheimer
Luisi,Simone Bonato
Sant'ana Filho,Manoel
author_role author
author2 Scarparo,Roberta Kochenborger
Pezzi,Ana Paula Weissheimer
Luisi,Simone Bonato
Sant'ana Filho,Manoel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Fachin,Elaine Vianna Freitas
Scarparo,Roberta Kochenborger
Pezzi,Ana Paula Weissheimer
Luisi,Simone Bonato
Sant'ana Filho,Manoel
dc.subject.por.fl_str_mv Inflammation
Dental pulp
Betamethasone
topic Inflammation
Dental pulp
Betamethasone
description OBJECTIVE: This study investigated the pulpal effect of topically applied betamethasone to the dentin of rat molars in the vascular phase of inflammation. MATERIAL AND METHODS: Deep cavities were prepared on the occlusal face of the maxillary right and left 1st molars with non-refrigerated inverted-cone steel burs at low speed. Three groups were formed: Group I was composed of right 1st molars; Group II was composed of left 1st molars that received the application of a drop of betamethasone on dentin surface for 5 min; and Group III (control) was composed of right 2nd molars that received no cavity preparation or betamethasone application. Changes in the vascular characteristics of the pulp tissue were checked by calculating the pulp vascular area in relation to its total area and the number of blood vessels per unit area. Data were subjected to ANOVA and Tukey's test (?=0.05). RESULTS: Group I presented a significantly larger number of vessels (p<0.05) than Group II. Regarding the vascular/total area ratio (%), Group I presented statistically significantly higher values (p=0.01) than Groups II and III. CONCLUSION: Betamethasone applied on the dentin of rat teeth proved to reduce the vascular phase of pulp inflammation regarding vessel diameter and number of blood vessels.
publishDate 2009
dc.date.none.fl_str_mv 2009-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572009000400012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1678-77572009000400012
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
dc.source.none.fl_str_mv Journal of Applied Oral Science v.17 n.4 2009
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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