Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/3388 |
Resumo: | OBJECTIVE: The objective of this study was to evaluate the incidence of adverse effects reported by adolescents following 14 days of use of a mouthrinse containing 0.05% NaF+0.12% chlorhexidine. METHODS: This double-blind study was developed as part of a randomized clinical trial. The adolescents enrolled to the study were randomly divided into two groups to use either: 0.05% NaF+0.12% chlorhexidine (G1, n=85) or 0.05% NaF (G2, n=85). Both groups used a 10mL solution of the mouthwash during 1 minute daily for 2 weeks under supervision. After that period, the subject's acceptance of taste was measured using a verbal descriptive scale (Labeled Magnitude Scale - LMS)11. Participants were also interviewed regarding the occurrence of possible adverse effects during treatment (temporary palate disorders, tooth staining or unpleasant taste). The proportional differences between the groups were tested using the chi-square test. RESULTS: Palate changes were reported by 26% of participants of each group; 17.7% of G1 and 32% of G2 reported an unpleasant taste (p = 0.062), while staining was reported by 55% of G1 and 68.9% of G2 (p = 0.117). Absenteeism rates were similar in both groups (G1= 2.58 ± 2.69; G2=2.81 ± 2.39), p=0.362. CONCLUSION: adherence was high in both groups and side effects reported by subjects were not perceived by them as being important. Since subjects' acceptance and compliance is fundamental to the success of an oral health program, chlorhexidine-fluoride could be a useful resource in a program of plaque control. |
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Journal of applied oral science (Online) |
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Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program Percepção de efeitos adversos por adolescentes em um programa preventivo de saúde bucal, a base de clorexidina e fluoreto Enxagüatórios bucaisClorexidinaefeitos adversosEnsaio clínico randomizadoMouthwashesChlorhexidineadverse effectsRandomized clinical trials OBJECTIVE: The objective of this study was to evaluate the incidence of adverse effects reported by adolescents following 14 days of use of a mouthrinse containing 0.05% NaF+0.12% chlorhexidine. METHODS: This double-blind study was developed as part of a randomized clinical trial. The adolescents enrolled to the study were randomly divided into two groups to use either: 0.05% NaF+0.12% chlorhexidine (G1, n=85) or 0.05% NaF (G2, n=85). Both groups used a 10mL solution of the mouthwash during 1 minute daily for 2 weeks under supervision. After that period, the subject's acceptance of taste was measured using a verbal descriptive scale (Labeled Magnitude Scale - LMS)11. Participants were also interviewed regarding the occurrence of possible adverse effects during treatment (temporary palate disorders, tooth staining or unpleasant taste). The proportional differences between the groups were tested using the chi-square test. RESULTS: Palate changes were reported by 26% of participants of each group; 17.7% of G1 and 32% of G2 reported an unpleasant taste (p = 0.062), while staining was reported by 55% of G1 and 68.9% of G2 (p = 0.117). Absenteeism rates were similar in both groups (G1= 2.58 ± 2.69; G2=2.81 ± 2.39), p=0.362. CONCLUSION: adherence was high in both groups and side effects reported by subjects were not perceived by them as being important. Since subjects' acceptance and compliance is fundamental to the success of an oral health program, chlorhexidine-fluoride could be a useful resource in a program of plaque control. OBJETIVO: Este estudo se propôs a calcular taxa de efeitos adversos após 14 dias de uso de solução de bochecho de NaF 0,05% + clorexidina 0,12% realizados por adolescentes. MÉTODOS: Este estudo duplo-cego foi desenvolvido como parte de um ensaio clínico randomizado. Os adolescentes foram divididos aleatoriamente em dois grupos: NaF 0,05% + clorexidina 0,12% (G1) ou NaF 0,05%, (G2) de 85 estudantes cada que bochecharam diariamente, 10mL de solução sob supervisão, durante 1 minuto, por 2 semanas. Após esse período, a aceitação dos participantes ao gosto das soluções foi avaliada através de uma escala descritiva verbal - (LMS)11. Os participantes foram entrevistados também quanto a possíveis efeitos adversos acontecidos durante tratamentos (desordens temporárias de paladar, manchamento dental e o gosto de soluções desagradáveis). As diferenças entre proporções em ambos os grupos foram testadas pelo teste do qui-quadrado. RESULTADOS: Alteração de paladar foi informada por 26% dos estudantes de cada grupo; 17,7% dos G1 e 32% do G2 notaram o gosto desagradável (p = 0,062); manchas foram observadas por 55% dos G1 e 68,9% dos G2 (p = 0,117) e, as taxas de absenteísmo foram semelhantes (G1 = 2,58±2,69; G2=2,81(2,39), p=0,362. CONCLUSÃO: A aderência dos participantes foi alta e os efeitos colaterais percebidos não pareceram importantes pelos adolescentes nos dois grupos. Implicação prática: porquanto a aceitação e aderência dos participantes são fundamentais para o sucesso de um programa de saúde bucal, a associação da clorexidina-fluoreto poderia ser um recurso adicional favorável dentro de um programa de controle de placa. Universidade de São Paulo. Faculdade de Odontologia de Bauru2006-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/338810.1590/S1678-77572006000400015Journal of Applied Oral Science; Vol. 14 No. 4 (2006); 291-296 Journal of Applied Oral Science; Vol. 14 Núm. 4 (2006); 291-296 Journal of Applied Oral Science; v. 14 n. 4 (2006); 291-296 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3388/4078Copyright (c) 2006 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessGuimaraes, Ana Rita DuartePeres, Marco AurélioVieira, Ricardo de SousaFerreira, Rodrigo MelinRamos-Jorge, Maria LetíciaApolinario, SaraDebom, Anderson2012-04-27T11:54:43Zoai:revistas.usp.br:article/3388Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T11:54:43Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program Percepção de efeitos adversos por adolescentes em um programa preventivo de saúde bucal, a base de clorexidina e fluoreto |
title |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program |
spellingShingle |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program Guimaraes, Ana Rita Duarte Enxagüatórios bucais Clorexidina efeitos adversos Ensaio clínico randomizado Mouthwashes Chlorhexidine adverse effects Randomized clinical trials |
title_short |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program |
title_full |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program |
title_fullStr |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program |
title_full_unstemmed |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program |
title_sort |
Self-perception of side effects by adolescents in a chlorhexidine-fluoride-based preventive oral health program |
author |
Guimaraes, Ana Rita Duarte |
author_facet |
Guimaraes, Ana Rita Duarte Peres, Marco Aurélio Vieira, Ricardo de Sousa Ferreira, Rodrigo Melin Ramos-Jorge, Maria Letícia Apolinario, Sara Debom, Anderson |
author_role |
author |
author2 |
Peres, Marco Aurélio Vieira, Ricardo de Sousa Ferreira, Rodrigo Melin Ramos-Jorge, Maria Letícia Apolinario, Sara Debom, Anderson |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Guimaraes, Ana Rita Duarte Peres, Marco Aurélio Vieira, Ricardo de Sousa Ferreira, Rodrigo Melin Ramos-Jorge, Maria Letícia Apolinario, Sara Debom, Anderson |
dc.subject.por.fl_str_mv |
Enxagüatórios bucais Clorexidina efeitos adversos Ensaio clínico randomizado Mouthwashes Chlorhexidine adverse effects Randomized clinical trials |
topic |
Enxagüatórios bucais Clorexidina efeitos adversos Ensaio clínico randomizado Mouthwashes Chlorhexidine adverse effects Randomized clinical trials |
description |
OBJECTIVE: The objective of this study was to evaluate the incidence of adverse effects reported by adolescents following 14 days of use of a mouthrinse containing 0.05% NaF+0.12% chlorhexidine. METHODS: This double-blind study was developed as part of a randomized clinical trial. The adolescents enrolled to the study were randomly divided into two groups to use either: 0.05% NaF+0.12% chlorhexidine (G1, n=85) or 0.05% NaF (G2, n=85). Both groups used a 10mL solution of the mouthwash during 1 minute daily for 2 weeks under supervision. After that period, the subject's acceptance of taste was measured using a verbal descriptive scale (Labeled Magnitude Scale - LMS)11. Participants were also interviewed regarding the occurrence of possible adverse effects during treatment (temporary palate disorders, tooth staining or unpleasant taste). The proportional differences between the groups were tested using the chi-square test. RESULTS: Palate changes were reported by 26% of participants of each group; 17.7% of G1 and 32% of G2 reported an unpleasant taste (p = 0.062), while staining was reported by 55% of G1 and 68.9% of G2 (p = 0.117). Absenteeism rates were similar in both groups (G1= 2.58 ± 2.69; G2=2.81 ± 2.39), p=0.362. CONCLUSION: adherence was high in both groups and side effects reported by subjects were not perceived by them as being important. Since subjects' acceptance and compliance is fundamental to the success of an oral health program, chlorhexidine-fluoride could be a useful resource in a program of plaque control. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3388 10.1590/S1678-77572006000400015 |
url |
https://www.revistas.usp.br/jaos/article/view/3388 |
identifier_str_mv |
10.1590/S1678-77572006000400015 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3388/4078 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2006 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2006 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 14 No. 4 (2006); 291-296 Journal of Applied Oral Science; Vol. 14 Núm. 4 (2006); 291-296 Journal of Applied Oral Science; v. 14 n. 4 (2006); 291-296 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221672791343104 |