Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser

Detalhes bibliográficos
Autor(a) principal: BADARÓ,Maurício Malheiros
Data de Publicação: 2017
Outros Autores: SALLES,Marcela Moreira, LEITE,Vanessa Maria Fagundes, ARRUDA,Carolina Noronha Ferraz de, OLIVEIRA,Viviane de Cássia, NASCIMENTO,Cássio do, SOUZA,Raphael Freitas de, PARANHOS,Helena de Freitas de Oliveira, SILVA-LOVATO,Cláudia Helena
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300324
Resumo: Abstract The development of opportunistic infections due to poor denture hygiene conditions justified the search for effective hygiene protocols for controlling denture biofilm. Objective This study evaluated Ricinus communis and sodium hypochlorite solutions in terms of biofilm removal ability, remission of candidiasis, antimicrobial activity, and participant satisfaction. Material and Methods It was conducted a controlled clinical trial, randomized, double-blind, and crossover. Sixty-four denture wearers with (n=24) and without candidiasis (n=40) were instructed to brush (3 times/day) and immerse their dentures (20 min/day) in different storage solutions (S1 / S2: 0.25% / 0.5% sodium hypochlorite; S3: 10% R. communis; S4: Saline).The trial period for each solution was seven days and a washout period of seven days was used before starting the use of another solution. The variables were analyzed at baseline and after each trial period. The biofilm of inner surfaces of maxillary dentures was disclosed, photographed, and total and dyed areas were measured (Image Tool software). The percentage of biofilm was calculated. Remission of candidiasis was assessed by visual scale and score were attributed. Antimicrobial activity was assessed by the DNA-Checkerboard hybridization method. Patient satisfaction was measured using a questionnaire. Results S1 (4.41±7.98%) and S2 (2.93±5.23%) were more effective then S3 (6.95±10.93%) in biofilm remotion(P<0.0001). All solutions were different from the control (11.07±11.99%). S3 was the most effective solution in remission of candidiasis (50%), followed by S1 (46%). Concerning antimicrobial action, S1/S2 were similar and resulted in the lowest microorganism mean count (P=0.04), followed by S3. No significant differences were found with patient’s satisfaction. Conclusions 10% R. communis and 0.25% sodium hypochlorite were effective in biofilm removal, causing remission of candidiasis and reducing the formation of microbial colonies in denture surfaces. All solutions were approved by patients.
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spelling Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanserDentureBiofilmsCandidiasisDisinfectionAbstract The development of opportunistic infections due to poor denture hygiene conditions justified the search for effective hygiene protocols for controlling denture biofilm. Objective This study evaluated Ricinus communis and sodium hypochlorite solutions in terms of biofilm removal ability, remission of candidiasis, antimicrobial activity, and participant satisfaction. Material and Methods It was conducted a controlled clinical trial, randomized, double-blind, and crossover. Sixty-four denture wearers with (n=24) and without candidiasis (n=40) were instructed to brush (3 times/day) and immerse their dentures (20 min/day) in different storage solutions (S1 / S2: 0.25% / 0.5% sodium hypochlorite; S3: 10% R. communis; S4: Saline).The trial period for each solution was seven days and a washout period of seven days was used before starting the use of another solution. The variables were analyzed at baseline and after each trial period. The biofilm of inner surfaces of maxillary dentures was disclosed, photographed, and total and dyed areas were measured (Image Tool software). The percentage of biofilm was calculated. Remission of candidiasis was assessed by visual scale and score were attributed. Antimicrobial activity was assessed by the DNA-Checkerboard hybridization method. Patient satisfaction was measured using a questionnaire. Results S1 (4.41±7.98%) and S2 (2.93±5.23%) were more effective then S3 (6.95±10.93%) in biofilm remotion(P<0.0001). All solutions were different from the control (11.07±11.99%). S3 was the most effective solution in remission of candidiasis (50%), followed by S1 (46%). Concerning antimicrobial action, S1/S2 were similar and resulted in the lowest microorganism mean count (P=0.04), followed by S3. No significant differences were found with patient’s satisfaction. Conclusions 10% R. communis and 0.25% sodium hypochlorite were effective in biofilm removal, causing remission of candidiasis and reducing the formation of microbial colonies in denture surfaces. All solutions were approved by patients.Faculdade De Odontologia De Bauru - USP2017-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300324Journal of Applied Oral Science v.25 n.3 2017reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/1678-7757-2016-0222info:eu-repo/semantics/openAccessBADARÓ,Maurício MalheirosSALLES,Marcela MoreiraLEITE,Vanessa Maria FagundesARRUDA,Carolina Noronha Ferraz deOLIVEIRA,Viviane de CássiaNASCIMENTO,Cássio doSOUZA,Raphael Freitas dePARANHOS,Helena de Freitas de OliveiraSILVA-LOVATO,Cláudia Helenaeng2017-08-30T00:00:00Zoai:scielo:S1678-77572017000300324Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2017-08-30T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
title Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
spellingShingle Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
BADARÓ,Maurício Malheiros
Denture
Biofilms
Candidiasis
Disinfection
title_short Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
title_full Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
title_fullStr Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
title_full_unstemmed Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
title_sort Clinical trial for evaluation of Ricinus communis and sodium hypochlorite as denture cleanser
author BADARÓ,Maurício Malheiros
author_facet BADARÓ,Maurício Malheiros
SALLES,Marcela Moreira
LEITE,Vanessa Maria Fagundes
ARRUDA,Carolina Noronha Ferraz de
OLIVEIRA,Viviane de Cássia
NASCIMENTO,Cássio do
SOUZA,Raphael Freitas de
PARANHOS,Helena de Freitas de Oliveira
SILVA-LOVATO,Cláudia Helena
author_role author
author2 SALLES,Marcela Moreira
LEITE,Vanessa Maria Fagundes
ARRUDA,Carolina Noronha Ferraz de
OLIVEIRA,Viviane de Cássia
NASCIMENTO,Cássio do
SOUZA,Raphael Freitas de
PARANHOS,Helena de Freitas de Oliveira
SILVA-LOVATO,Cláudia Helena
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv BADARÓ,Maurício Malheiros
SALLES,Marcela Moreira
LEITE,Vanessa Maria Fagundes
ARRUDA,Carolina Noronha Ferraz de
OLIVEIRA,Viviane de Cássia
NASCIMENTO,Cássio do
SOUZA,Raphael Freitas de
PARANHOS,Helena de Freitas de Oliveira
SILVA-LOVATO,Cláudia Helena
dc.subject.por.fl_str_mv Denture
Biofilms
Candidiasis
Disinfection
topic Denture
Biofilms
Candidiasis
Disinfection
description Abstract The development of opportunistic infections due to poor denture hygiene conditions justified the search for effective hygiene protocols for controlling denture biofilm. Objective This study evaluated Ricinus communis and sodium hypochlorite solutions in terms of biofilm removal ability, remission of candidiasis, antimicrobial activity, and participant satisfaction. Material and Methods It was conducted a controlled clinical trial, randomized, double-blind, and crossover. Sixty-four denture wearers with (n=24) and without candidiasis (n=40) were instructed to brush (3 times/day) and immerse their dentures (20 min/day) in different storage solutions (S1 / S2: 0.25% / 0.5% sodium hypochlorite; S3: 10% R. communis; S4: Saline).The trial period for each solution was seven days and a washout period of seven days was used before starting the use of another solution. The variables were analyzed at baseline and after each trial period. The biofilm of inner surfaces of maxillary dentures was disclosed, photographed, and total and dyed areas were measured (Image Tool software). The percentage of biofilm was calculated. Remission of candidiasis was assessed by visual scale and score were attributed. Antimicrobial activity was assessed by the DNA-Checkerboard hybridization method. Patient satisfaction was measured using a questionnaire. Results S1 (4.41±7.98%) and S2 (2.93±5.23%) were more effective then S3 (6.95±10.93%) in biofilm remotion(P<0.0001). All solutions were different from the control (11.07±11.99%). S3 was the most effective solution in remission of candidiasis (50%), followed by S1 (46%). Concerning antimicrobial action, S1/S2 were similar and resulted in the lowest microorganism mean count (P=0.04), followed by S3. No significant differences were found with patient’s satisfaction. Conclusions 10% R. communis and 0.25% sodium hypochlorite were effective in biofilm removal, causing remission of candidiasis and reducing the formation of microbial colonies in denture surfaces. All solutions were approved by patients.
publishDate 2017
dc.date.none.fl_str_mv 2017-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300324
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000300324
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-7757-2016-0222
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
dc.source.none.fl_str_mv Journal of Applied Oral Science v.25 n.3 2017
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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