Oral cancer stem cells - properties and consequences

Detalhes bibliográficos
Autor(a) principal: Rodini,Camila Oliveira
Data de Publicação: 2017
Outros Autores: Lopes,Nathália Martins, Lara,Vanessa Soares, Mackenzie,Ian Campbell
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000600708
Resumo: Abstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.
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spelling Oral cancer stem cells - properties and consequencesNeoplastic stem cellsMouth neoplasmsEpithelial-mesenchymal transitionNeoplasm metastasisSquamous cell carcinomaAbstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.Faculdade De Odontologia De Bauru - USP2017-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000600708Journal of Applied Oral Science v.25 n.6 2017reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/1678-7757-2016-0665info:eu-repo/semantics/openAccessRodini,Camila OliveiraLopes,Nathália MartinsLara,Vanessa SoaresMackenzie,Ian Campbelleng2017-11-27T00:00:00Zoai:scielo:S1678-77572017000600708Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2017-11-27T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Oral cancer stem cells - properties and consequences
title Oral cancer stem cells - properties and consequences
spellingShingle Oral cancer stem cells - properties and consequences
Rodini,Camila Oliveira
Neoplastic stem cells
Mouth neoplasms
Epithelial-mesenchymal transition
Neoplasm metastasis
Squamous cell carcinoma
title_short Oral cancer stem cells - properties and consequences
title_full Oral cancer stem cells - properties and consequences
title_fullStr Oral cancer stem cells - properties and consequences
title_full_unstemmed Oral cancer stem cells - properties and consequences
title_sort Oral cancer stem cells - properties and consequences
author Rodini,Camila Oliveira
author_facet Rodini,Camila Oliveira
Lopes,Nathália Martins
Lara,Vanessa Soares
Mackenzie,Ian Campbell
author_role author
author2 Lopes,Nathália Martins
Lara,Vanessa Soares
Mackenzie,Ian Campbell
author2_role author
author
author
dc.contributor.author.fl_str_mv Rodini,Camila Oliveira
Lopes,Nathália Martins
Lara,Vanessa Soares
Mackenzie,Ian Campbell
dc.subject.por.fl_str_mv Neoplastic stem cells
Mouth neoplasms
Epithelial-mesenchymal transition
Neoplasm metastasis
Squamous cell carcinoma
topic Neoplastic stem cells
Mouth neoplasms
Epithelial-mesenchymal transition
Neoplasm metastasis
Squamous cell carcinoma
description Abstract Research on cancer stem cells (CSCs) has greatly increased in the field of medicine and pathology; however, some conceptual misunderstandings are still present among the public as well as within the general scientific community that is not yet familiar with the subject. The very first problem is the misinterpretation of CSCs as a synonym of their normal counterparts, the well-known stem cells (SCs). Particularly in Dentistry, another common mistake is the misinterpretation of oral CSCs as normal tooth-derived SCs. The present review aims to clarify important concepts related to normal SCs and CSCs, as well as discuss the relevance of CSCs to the development, metastasis and therapy resistance of oral squamous cell carcinoma.
publishDate 2017
dc.date.none.fl_str_mv 2017-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000600708
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572017000600708
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-7757-2016-0665
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
dc.source.none.fl_str_mv Journal of Applied Oral Science v.25 n.6 2017
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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