Goldenhar syndrome: clinical features with orofacial emphasis

Detalhes bibliográficos
Autor(a) principal: Martelli-Júnior, Hercílio
Data de Publicação: 2010
Outros Autores: Miranda, Roseli Teixeira de, Fernandes, Cassandro Moreira, Bonan, Paulo Rogério Ferreti, Paranaíba, Lívia Máris Ribeiro, Graner, Edgard, Coletta, Ricardo D.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3859
Resumo: OBJECTIVES: Goldenhar syndrome (GS) is a relatively common developmental disorder characterized by craniofacial anomalies in association with vertebral, cardiac, renal, and central nervous system defects. This paper describes GS features with special emphasis on oral characteristics. MATERIAL AND METHODS: The clinical features of 6 patients with GS aged 3 months to 12 years are described, and a brief review of the literature about this genetic disorder is presented. RESULTS: All patients demonstrated the classical triad of GS, including mandibular hypoplasia resulting in facial asymmetry, ear and/or eye malformation, and vertebral anomalies. In addition, renal and gastrointestinal abnormalities were observed in 2 patients. Regarding the oral involvement, 2 patients presented cleft lip and palate, and 1 patient had temporomandibular joint malformation. Malocclusion was found in all patients. CONCLUSION: Our orofacial findings correlate with the reported cases in the literature, and point out that after diagnosis GS patients need to be examined for systemic abnormalities.
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spelling Goldenhar syndrome: clinical features with orofacial emphasis Goldenhar syndromeMandibleFacial asymmetry OBJECTIVES: Goldenhar syndrome (GS) is a relatively common developmental disorder characterized by craniofacial anomalies in association with vertebral, cardiac, renal, and central nervous system defects. This paper describes GS features with special emphasis on oral characteristics. MATERIAL AND METHODS: The clinical features of 6 patients with GS aged 3 months to 12 years are described, and a brief review of the literature about this genetic disorder is presented. RESULTS: All patients demonstrated the classical triad of GS, including mandibular hypoplasia resulting in facial asymmetry, ear and/or eye malformation, and vertebral anomalies. In addition, renal and gastrointestinal abnormalities were observed in 2 patients. Regarding the oral involvement, 2 patients presented cleft lip and palate, and 1 patient had temporomandibular joint malformation. Malocclusion was found in all patients. CONCLUSION: Our orofacial findings correlate with the reported cases in the literature, and point out that after diagnosis GS patients need to be examined for systemic abnormalities. Universidade de São Paulo. Faculdade de Odontologia de Bauru2010-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/385910.1590/S1678-77572010000600019Journal of Applied Oral Science; Vol. 18 No. 6 (2010); 646-649 Journal of Applied Oral Science; Vol. 18 Núm. 6 (2010); 646-649 Journal of Applied Oral Science; v. 18 n. 6 (2010); 646-649 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3859/4549Copyright (c) 2010 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessMartelli-Júnior, HercílioMiranda, Roseli Teixeira deFernandes, Cassandro MoreiraBonan, Paulo Rogério FerretiParanaíba, Lívia Máris RibeiroGraner, EdgardColetta, Ricardo D.2012-04-27T12:11:57Zoai:revistas.usp.br:article/3859Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:11:57Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Goldenhar syndrome: clinical features with orofacial emphasis
title Goldenhar syndrome: clinical features with orofacial emphasis
spellingShingle Goldenhar syndrome: clinical features with orofacial emphasis
Martelli-Júnior, Hercílio
Goldenhar syndrome
Mandible
Facial asymmetry
title_short Goldenhar syndrome: clinical features with orofacial emphasis
title_full Goldenhar syndrome: clinical features with orofacial emphasis
title_fullStr Goldenhar syndrome: clinical features with orofacial emphasis
title_full_unstemmed Goldenhar syndrome: clinical features with orofacial emphasis
title_sort Goldenhar syndrome: clinical features with orofacial emphasis
author Martelli-Júnior, Hercílio
author_facet Martelli-Júnior, Hercílio
Miranda, Roseli Teixeira de
Fernandes, Cassandro Moreira
Bonan, Paulo Rogério Ferreti
Paranaíba, Lívia Máris Ribeiro
Graner, Edgard
Coletta, Ricardo D.
author_role author
author2 Miranda, Roseli Teixeira de
Fernandes, Cassandro Moreira
Bonan, Paulo Rogério Ferreti
Paranaíba, Lívia Máris Ribeiro
Graner, Edgard
Coletta, Ricardo D.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martelli-Júnior, Hercílio
Miranda, Roseli Teixeira de
Fernandes, Cassandro Moreira
Bonan, Paulo Rogério Ferreti
Paranaíba, Lívia Máris Ribeiro
Graner, Edgard
Coletta, Ricardo D.
dc.subject.por.fl_str_mv Goldenhar syndrome
Mandible
Facial asymmetry
topic Goldenhar syndrome
Mandible
Facial asymmetry
description OBJECTIVES: Goldenhar syndrome (GS) is a relatively common developmental disorder characterized by craniofacial anomalies in association with vertebral, cardiac, renal, and central nervous system defects. This paper describes GS features with special emphasis on oral characteristics. MATERIAL AND METHODS: The clinical features of 6 patients with GS aged 3 months to 12 years are described, and a brief review of the literature about this genetic disorder is presented. RESULTS: All patients demonstrated the classical triad of GS, including mandibular hypoplasia resulting in facial asymmetry, ear and/or eye malformation, and vertebral anomalies. In addition, renal and gastrointestinal abnormalities were observed in 2 patients. Regarding the oral involvement, 2 patients presented cleft lip and palate, and 1 patient had temporomandibular joint malformation. Malocclusion was found in all patients. CONCLUSION: Our orofacial findings correlate with the reported cases in the literature, and point out that after diagnosis GS patients need to be examined for systemic abnormalities.
publishDate 2010
dc.date.none.fl_str_mv 2010-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3859
10.1590/S1678-77572010000600019
url https://www.revistas.usp.br/jaos/article/view/3859
identifier_str_mv 10.1590/S1678-77572010000600019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3859/4549
dc.rights.driver.fl_str_mv Copyright (c) 2010 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2010 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 18 No. 6 (2010); 646-649
Journal of Applied Oral Science; Vol. 18 Núm. 6 (2010); 646-649
Journal of Applied Oral Science; v. 18 n. 6 (2010); 646-649
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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