At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/221871 |
Resumo: | Objectives: This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration. Methodology: A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whitening agent product used: blue covarine dentifrices (BCD), hydrogen peroxide dentifrices (HPD), dentifrices without bleaching agents (CD, negative control), and 10% carbamide peroxide (CP10, positive control) for at-home bleaching. The consumer/patient perspective was adopted, macro-costing techniques were used and a decision tree model was performed considering the costs in the American and Brazilian markets. The color change evaluation (ΔE*ab) was used to calculate the effectiveness of tooth bleaching. A probabilistic analysis was performed using a Monte Carlo simulation and incremental cost-effectiveness ratios were obtained. Results: CP10 resulted in the highest cost-effectiveness compared to the use of dentifrices in both markets. In Brazil, HPD was more cost-effective than BCD and CD. In the US, the increased costs of HPD and BCD did not generate any whitening benefit compared to CD. Conclusions: CP10 was more cost-effective than BCD and HPD for tooth bleaching from the perspectives of the Brazilian and American markets. Decision-making should consider the use of CP10 for treating tooth discoloration. |
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Journal of applied oral science (Online) |
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At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysisCost-benefit analysisDentifricesToothpastesCarbamide peroxideTooth bleachingObjectives: This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration. Methodology: A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whitening agent product used: blue covarine dentifrices (BCD), hydrogen peroxide dentifrices (HPD), dentifrices without bleaching agents (CD, negative control), and 10% carbamide peroxide (CP10, positive control) for at-home bleaching. The consumer/patient perspective was adopted, macro-costing techniques were used and a decision tree model was performed considering the costs in the American and Brazilian markets. The color change evaluation (ΔE*ab) was used to calculate the effectiveness of tooth bleaching. A probabilistic analysis was performed using a Monte Carlo simulation and incremental cost-effectiveness ratios were obtained. Results: CP10 resulted in the highest cost-effectiveness compared to the use of dentifrices in both markets. In Brazil, HPD was more cost-effective than BCD and CD. In the US, the increased costs of HPD and BCD did not generate any whitening benefit compared to CD. Conclusions: CP10 was more cost-effective than BCD and HPD for tooth bleaching from the perspectives of the Brazilian and American markets. Decision-making should consider the use of CP10 for treating tooth discoloration.Universidade de São Paulo. Faculdade de Odontologia de Bauru2024-02-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/22187110.1590/1678-7757-2023-0336Journal of Applied Oral Science; Vol. 32 (2024); e20230336Journal of Applied Oral Science; v. 32 (2024); e20230336Journal of Applied Oral Science; Vol. 32 (2024); e202303361678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/221871/202744Copyright (c) 2024 Journal of Applied Oral Sciencehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Mariana Evangelista Silva, Rênnis Oliveira daCavalcanti, Yuri WanderleyMeireles, Sônia Saeger2024-03-26T14:46:33Zoai:revistas.usp.br:article/221871Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2024-03-26T14:46:33Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
title |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
spellingShingle |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis Santos, Mariana Evangelista Cost-benefit analysis Dentifrices Toothpastes Carbamide peroxide Tooth bleaching |
title_short |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
title_full |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
title_fullStr |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
title_full_unstemmed |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
title_sort |
At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis |
author |
Santos, Mariana Evangelista |
author_facet |
Santos, Mariana Evangelista Silva, Rênnis Oliveira da Cavalcanti, Yuri Wanderley Meireles, Sônia Saeger |
author_role |
author |
author2 |
Silva, Rênnis Oliveira da Cavalcanti, Yuri Wanderley Meireles, Sônia Saeger |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Santos, Mariana Evangelista Silva, Rênnis Oliveira da Cavalcanti, Yuri Wanderley Meireles, Sônia Saeger |
dc.subject.por.fl_str_mv |
Cost-benefit analysis Dentifrices Toothpastes Carbamide peroxide Tooth bleaching |
topic |
Cost-benefit analysis Dentifrices Toothpastes Carbamide peroxide Tooth bleaching |
description |
Objectives: This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration. Methodology: A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whitening agent product used: blue covarine dentifrices (BCD), hydrogen peroxide dentifrices (HPD), dentifrices without bleaching agents (CD, negative control), and 10% carbamide peroxide (CP10, positive control) for at-home bleaching. The consumer/patient perspective was adopted, macro-costing techniques were used and a decision tree model was performed considering the costs in the American and Brazilian markets. The color change evaluation (ΔE*ab) was used to calculate the effectiveness of tooth bleaching. A probabilistic analysis was performed using a Monte Carlo simulation and incremental cost-effectiveness ratios were obtained. Results: CP10 resulted in the highest cost-effectiveness compared to the use of dentifrices in both markets. In Brazil, HPD was more cost-effective than BCD and CD. In the US, the increased costs of HPD and BCD did not generate any whitening benefit compared to CD. Conclusions: CP10 was more cost-effective than BCD and HPD for tooth bleaching from the perspectives of the Brazilian and American markets. Decision-making should consider the use of CP10 for treating tooth discoloration. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-02-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/221871 10.1590/1678-7757-2023-0336 |
url |
https://www.revistas.usp.br/jaos/article/view/221871 |
identifier_str_mv |
10.1590/1678-7757-2023-0336 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/221871/202744 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2024 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2024 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 32 (2024); e20230336 Journal of Applied Oral Science; v. 32 (2024); e20230336 Journal of Applied Oral Science; Vol. 32 (2024); e20230336 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221670417367040 |