Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/201150 |
Resumo: | The repair of bone defects raises the interest of investigators in several health specialties. Grafting techniques with bone substitutes and laser therapies have been investigated to replace autogenous bone and accelerate the bone healing process. Objective: To evaluate the effect of photobiomodulation therapy (PBMT) associated with guided bone regeneration (GBR) in critical size defects. Material and Methods: The study was conducted on 80 male rats (Rattus norvegicus albinus, Wistar) submitted to surgical creation of a critical size defect on the calvaria, divided into eight study groups: group C (control - only blood clot); group M (collagen membrane); group PBMT (photobiomodulation therapy); group AB (autogenous bone); group AB+PBMT; group AB+M; group PBMT+M; group AB+PBMT+M. The animals were killed 30 days postoperatively. After tissue processing, bone regeneration was evaluated by histomorphometric analysis and statistical analyses were performed (Tukey test, p<0.05). Results: All groups had greater area of newly formed bone compared to group C (9.96±4.49%). The group PBMT+M (achieved the greater quantity of new bone (64.09±7.62%), followed by groups PBMT (47.67±8.66%), M (47.43±15.73%), AB+PBMT (39.15±16.72%) and AB+PBMT+M (35.82±7.68%). After group C, the groups AB (25.10±16.59%) and AB+M (22.72±13.83%) had the smallest quantities of newly formed bone. The area of remaining particles did not have statistically significant difference between groups AB+M (14.93±8.92%) and AB+PBMT+M (14.76±6.58%). Conclusion: The PBMT utilization may be effective for bone repair, when associated with bone regeneration techniques. |
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Journal of applied oral science (Online) |
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Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo studyAutograftBone regenerationLasersThe repair of bone defects raises the interest of investigators in several health specialties. Grafting techniques with bone substitutes and laser therapies have been investigated to replace autogenous bone and accelerate the bone healing process. Objective: To evaluate the effect of photobiomodulation therapy (PBMT) associated with guided bone regeneration (GBR) in critical size defects. Material and Methods: The study was conducted on 80 male rats (Rattus norvegicus albinus, Wistar) submitted to surgical creation of a critical size defect on the calvaria, divided into eight study groups: group C (control - only blood clot); group M (collagen membrane); group PBMT (photobiomodulation therapy); group AB (autogenous bone); group AB+PBMT; group AB+M; group PBMT+M; group AB+PBMT+M. The animals were killed 30 days postoperatively. After tissue processing, bone regeneration was evaluated by histomorphometric analysis and statistical analyses were performed (Tukey test, p<0.05). Results: All groups had greater area of newly formed bone compared to group C (9.96±4.49%). The group PBMT+M (achieved the greater quantity of new bone (64.09±7.62%), followed by groups PBMT (47.67±8.66%), M (47.43±15.73%), AB+PBMT (39.15±16.72%) and AB+PBMT+M (35.82±7.68%). After group C, the groups AB (25.10±16.59%) and AB+M (22.72±13.83%) had the smallest quantities of newly formed bone. The area of remaining particles did not have statistically significant difference between groups AB+M (14.93±8.92%) and AB+PBMT+M (14.76±6.58%). Conclusion: The PBMT utilization may be effective for bone repair, when associated with bone regeneration techniques.Universidade de São Paulo. Faculdade de Odontologia de Bauru2022-08-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/201150Journal of Applied Oral Science; Vol. 26 (2018); e20170244Journal of Applied Oral Science; Vol. 26 (2018); e20170244Journal of Applied Oral Science; v. 26 (2018); e201702441678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/201150/185293Copyright (c) 2022 Journal of Applied Oral Sciencehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessFreitas, Nicole Rosa deGuerrini, Luísa BellucoEsper, Luis AugustoSbrana, Michyele CristhianeDalben, Gisele da SilvaSoares, SimoneAlmeida, Ana Lúcia Pompéia Fraga de2022-08-17T18:31:08Zoai:revistas.usp.br:article/201150Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2022-08-17T18:31:08Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
title |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
spellingShingle |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study Freitas, Nicole Rosa de Autograft Bone regeneration Lasers |
title_short |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
title_full |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
title_fullStr |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
title_full_unstemmed |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
title_sort |
Evaluation of photobiomodulation therapy associated with guided bone regeneration in critical size defects. In vivo study |
author |
Freitas, Nicole Rosa de |
author_facet |
Freitas, Nicole Rosa de Guerrini, Luísa Belluco Esper, Luis Augusto Sbrana, Michyele Cristhiane Dalben, Gisele da Silva Soares, Simone Almeida, Ana Lúcia Pompéia Fraga de |
author_role |
author |
author2 |
Guerrini, Luísa Belluco Esper, Luis Augusto Sbrana, Michyele Cristhiane Dalben, Gisele da Silva Soares, Simone Almeida, Ana Lúcia Pompéia Fraga de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Freitas, Nicole Rosa de Guerrini, Luísa Belluco Esper, Luis Augusto Sbrana, Michyele Cristhiane Dalben, Gisele da Silva Soares, Simone Almeida, Ana Lúcia Pompéia Fraga de |
dc.subject.por.fl_str_mv |
Autograft Bone regeneration Lasers |
topic |
Autograft Bone regeneration Lasers |
description |
The repair of bone defects raises the interest of investigators in several health specialties. Grafting techniques with bone substitutes and laser therapies have been investigated to replace autogenous bone and accelerate the bone healing process. Objective: To evaluate the effect of photobiomodulation therapy (PBMT) associated with guided bone regeneration (GBR) in critical size defects. Material and Methods: The study was conducted on 80 male rats (Rattus norvegicus albinus, Wistar) submitted to surgical creation of a critical size defect on the calvaria, divided into eight study groups: group C (control - only blood clot); group M (collagen membrane); group PBMT (photobiomodulation therapy); group AB (autogenous bone); group AB+PBMT; group AB+M; group PBMT+M; group AB+PBMT+M. The animals were killed 30 days postoperatively. After tissue processing, bone regeneration was evaluated by histomorphometric analysis and statistical analyses were performed (Tukey test, p<0.05). Results: All groups had greater area of newly formed bone compared to group C (9.96±4.49%). The group PBMT+M (achieved the greater quantity of new bone (64.09±7.62%), followed by groups PBMT (47.67±8.66%), M (47.43±15.73%), AB+PBMT (39.15±16.72%) and AB+PBMT+M (35.82±7.68%). After group C, the groups AB (25.10±16.59%) and AB+M (22.72±13.83%) had the smallest quantities of newly formed bone. The area of remaining particles did not have statistically significant difference between groups AB+M (14.93±8.92%) and AB+PBMT+M (14.76±6.58%). Conclusion: The PBMT utilization may be effective for bone repair, when associated with bone regeneration techniques. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-08-17 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/201150 |
url |
https://www.revistas.usp.br/jaos/article/view/201150 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/201150/185293 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2022 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2022 Journal of Applied Oral Science http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 26 (2018); e20170244 Journal of Applied Oral Science; Vol. 26 (2018); e20170244 Journal of Applied Oral Science; v. 26 (2018); e20170244 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221683157565440 |