Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate

Detalhes bibliográficos
Autor(a) principal: Esteves, Jônatas Caldeira
Data de Publicação: 2011
Outros Autores: Borrasca, Albanir Gabriel, Aranega, Alessandra Marcondes, Garcia Junior, Idelmo Rangel, Magro Filho, Osvaldo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3949
Resumo: OBJECTIVE: The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive. MATERIAL AND METHODS: Thirty-two rats were divided into two groups (n=16), Group I - Control and Group II - Adhesive. Osteotomies were made at the right parietal bone for graft obtainment using a 4-mm-diameter trephine drill. Then, the bone segments were fixed with the adhesive in the parietal region of the opposite side to the donor site. After 10 and 30 days, 8 animals of each group were euthanized and the calvarias were laboratorially processed for obtaining hematoxylin and eosin-stained slides for histological and histometric analyses. RESULTS: An intense inflammatory reaction was observed at the 10-day period. At 30 days, this reaction was less intense, despite the presence of adhesive at the recipient-site/graft interface. Graft incorporation to the recipient site was observed only at the control group, which maintained the highest graft size at 10 and 30 days. CONCLUSIONS: Although the fragment was stable, the presence of adhesive in Group II did not allow graft incorporation to the recipient site, determining a localized, discrete and persistent inflammatory reaction.
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spelling Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate Tissue adhesivesCyanoacrylatesBone transplantation OBJECTIVE: The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive. MATERIAL AND METHODS: Thirty-two rats were divided into two groups (n=16), Group I - Control and Group II - Adhesive. Osteotomies were made at the right parietal bone for graft obtainment using a 4-mm-diameter trephine drill. Then, the bone segments were fixed with the adhesive in the parietal region of the opposite side to the donor site. After 10 and 30 days, 8 animals of each group were euthanized and the calvarias were laboratorially processed for obtaining hematoxylin and eosin-stained slides for histological and histometric analyses. RESULTS: An intense inflammatory reaction was observed at the 10-day period. At 30 days, this reaction was less intense, despite the presence of adhesive at the recipient-site/graft interface. Graft incorporation to the recipient site was observed only at the control group, which maintained the highest graft size at 10 and 30 days. CONCLUSIONS: Although the fragment was stable, the presence of adhesive in Group II did not allow graft incorporation to the recipient site, determining a localized, discrete and persistent inflammatory reaction. Universidade de São Paulo. Faculdade de Odontologia de Bauru2011-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/394910.1590/S1678-77572011000500016Journal of Applied Oral Science; Vol. 19 No. 5 (2011); 529-534 Journal of Applied Oral Science; Vol. 19 Núm. 5 (2011); 529-534 Journal of Applied Oral Science; v. 19 n. 5 (2011); 529-534 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3949/4639Copyright (c) 2011 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessEsteves, Jônatas CaldeiraBorrasca, Albanir GabrielAranega, Alessandra MarcondesGarcia Junior, Idelmo RangelMagro Filho, Osvaldo2012-04-27T12:15:50Zoai:revistas.usp.br:article/3949Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:15:50Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
title Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
spellingShingle Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
Esteves, Jônatas Caldeira
Tissue adhesives
Cyanoacrylates
Bone transplantation
title_short Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
title_full Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
title_fullStr Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
title_full_unstemmed Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
title_sort Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
author Esteves, Jônatas Caldeira
author_facet Esteves, Jônatas Caldeira
Borrasca, Albanir Gabriel
Aranega, Alessandra Marcondes
Garcia Junior, Idelmo Rangel
Magro Filho, Osvaldo
author_role author
author2 Borrasca, Albanir Gabriel
Aranega, Alessandra Marcondes
Garcia Junior, Idelmo Rangel
Magro Filho, Osvaldo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Esteves, Jônatas Caldeira
Borrasca, Albanir Gabriel
Aranega, Alessandra Marcondes
Garcia Junior, Idelmo Rangel
Magro Filho, Osvaldo
dc.subject.por.fl_str_mv Tissue adhesives
Cyanoacrylates
Bone transplantation
topic Tissue adhesives
Cyanoacrylates
Bone transplantation
description OBJECTIVE: The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive. MATERIAL AND METHODS: Thirty-two rats were divided into two groups (n=16), Group I - Control and Group II - Adhesive. Osteotomies were made at the right parietal bone for graft obtainment using a 4-mm-diameter trephine drill. Then, the bone segments were fixed with the adhesive in the parietal region of the opposite side to the donor site. After 10 and 30 days, 8 animals of each group were euthanized and the calvarias were laboratorially processed for obtaining hematoxylin and eosin-stained slides for histological and histometric analyses. RESULTS: An intense inflammatory reaction was observed at the 10-day period. At 30 days, this reaction was less intense, despite the presence of adhesive at the recipient-site/graft interface. Graft incorporation to the recipient site was observed only at the control group, which maintained the highest graft size at 10 and 30 days. CONCLUSIONS: Although the fragment was stable, the presence of adhesive in Group II did not allow graft incorporation to the recipient site, determining a localized, discrete and persistent inflammatory reaction.
publishDate 2011
dc.date.none.fl_str_mv 2011-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3949
10.1590/S1678-77572011000500016
url https://www.revistas.usp.br/jaos/article/view/3949
identifier_str_mv 10.1590/S1678-77572011000500016
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3949/4639
dc.rights.driver.fl_str_mv Copyright (c) 2011 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2011 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 19 No. 5 (2011); 529-534
Journal of Applied Oral Science; Vol. 19 Núm. 5 (2011); 529-534
Journal of Applied Oral Science; v. 19 n. 5 (2011); 529-534
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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