Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans

Detalhes bibliográficos
Autor(a) principal: Salgado, Alexandre Daher Yunes
Data de Publicação: 2006
Outros Autores: Maia, Juliana Lemos, Pereira, Sérgio Luís da Silva, Lemos, Telma Leda Gomes de, Mota, Olívia Morais de Lima
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: https://www.revistas.usp.br/jaos/article/view/3362
Resumo: OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant). The subjects were randomly assigned to use either the placebo gel (control group) or the test gel (experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI) and gingival bleeding index (GBI) were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI). CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis.
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spelling Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans Efeito antiplaca e antiinflamatório de um gel contendo extrato de romã: estudo clínico duplo-cego em humanos Placa bacterianaGengivitePunica granatum LinnDental plaqueGingivitisPunica granatum Linn OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant). The subjects were randomly assigned to use either the placebo gel (control group) or the test gel (experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI) and gingival bleeding index (GBI) were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI). CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis. OBJETIVOS: O efeito antiplaca e antigengivite de um gel contendo extrato de romã a 10% foi avaliado utilizando um modelo de gengivite experimental parcial em humanos. MÉTODOS: 23 indivíduos participaram voluntariamente deste estudo cruzado, duplo-cego, compreendendo dois períodos de 21 dias cada um. Uma moldeira de acrílico foi confeccionada para cada participante, a qual foi utilizada como carreadora dos géis sobre a área a ser avaliada (hemiarco inferior esquerdo). Os sujeitos foram aleatoriamente designados para usar o gel placebo (grupo controle) ou o gel teste (grupo experimental), sendo instruídos a colocar o gel na moldeira e esta sobre os dentes teste, escovando os outros normalmente três vezes ao dia. No dia 0 e dia 21 os índices de placa visível (IPV) e índice de sangramento gengival (ISG) foram registrados. RESULTADOS: Os resultados não demonstraram diferença estatística significante entre os grupos controle e experimental para nenhum dos índices. CONCLUSÕES: O gel contendo extrato de romã a 10% não foi eficiente em evitar a formação de placa bacteriana supragengival e prevenir a inflamação gengival. Universidade de São Paulo. Faculdade de Odontologia de Bauru2006-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/336210.1590/S1678-77572006000300003Journal of Applied Oral Science; Vol. 14 No. 3 (2006); 162-166 Journal of Applied Oral Science; Vol. 14 Núm. 3 (2006); 162-166 Journal of Applied Oral Science; v. 14 n. 3 (2006); 162-166 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3362/4052Copyright (c) 2006 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessSalgado, Alexandre Daher YunesMaia, Juliana LemosPereira, Sérgio Luís da SilvaLemos, Telma Leda Gomes deMota, Olívia Morais de Lima2012-04-27T11:53:47Zoai:revistas.usp.br:article/3362Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T11:53:47Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
Efeito antiplaca e antiinflamatório de um gel contendo extrato de romã: estudo clínico duplo-cego em humanos
title Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
spellingShingle Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
Salgado, Alexandre Daher Yunes
Placa bacteriana
Gengivite
Punica granatum Linn
Dental plaque
Gingivitis
Punica granatum Linn
title_short Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
title_full Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
title_fullStr Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
title_full_unstemmed Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
title_sort Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
author Salgado, Alexandre Daher Yunes
author_facet Salgado, Alexandre Daher Yunes
Maia, Juliana Lemos
Pereira, Sérgio Luís da Silva
Lemos, Telma Leda Gomes de
Mota, Olívia Morais de Lima
author_role author
author2 Maia, Juliana Lemos
Pereira, Sérgio Luís da Silva
Lemos, Telma Leda Gomes de
Mota, Olívia Morais de Lima
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Salgado, Alexandre Daher Yunes
Maia, Juliana Lemos
Pereira, Sérgio Luís da Silva
Lemos, Telma Leda Gomes de
Mota, Olívia Morais de Lima
dc.subject.por.fl_str_mv Placa bacteriana
Gengivite
Punica granatum Linn
Dental plaque
Gingivitis
Punica granatum Linn
topic Placa bacteriana
Gengivite
Punica granatum Linn
Dental plaque
Gingivitis
Punica granatum Linn
description OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant). The subjects were randomly assigned to use either the placebo gel (control group) or the test gel (experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI) and gingival bleeding index (GBI) were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI). CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis.
publishDate 2006
dc.date.none.fl_str_mv 2006-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3362
10.1590/S1678-77572006000300003
url https://www.revistas.usp.br/jaos/article/view/3362
identifier_str_mv 10.1590/S1678-77572006000300003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/jaos/article/view/3362/4052
dc.rights.driver.fl_str_mv Copyright (c) 2006 Journal of Applied Oral Science
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2006 Journal of Applied Oral Science
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Odontologia de Bauru
dc.source.none.fl_str_mv Journal of Applied Oral Science; Vol. 14 No. 3 (2006); 162-166
Journal of Applied Oral Science; Vol. 14 Núm. 3 (2006); 162-166
Journal of Applied Oral Science; v. 14 n. 3 (2006); 162-166
1678-7765
1678-7757
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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