Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/3362 |
Resumo: | OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant). The subjects were randomly assigned to use either the placebo gel (control group) or the test gel (experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI) and gingival bleeding index (GBI) were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI). CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis. |
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Journal of applied oral science (Online) |
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Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans Efeito antiplaca e antiinflamatório de um gel contendo extrato de romã: estudo clínico duplo-cego em humanos Placa bacterianaGengivitePunica granatum LinnDental plaqueGingivitisPunica granatum Linn OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant). The subjects were randomly assigned to use either the placebo gel (control group) or the test gel (experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI) and gingival bleeding index (GBI) were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI). CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis. OBJETIVOS: O efeito antiplaca e antigengivite de um gel contendo extrato de romã a 10% foi avaliado utilizando um modelo de gengivite experimental parcial em humanos. MÉTODOS: 23 indivíduos participaram voluntariamente deste estudo cruzado, duplo-cego, compreendendo dois períodos de 21 dias cada um. Uma moldeira de acrílico foi confeccionada para cada participante, a qual foi utilizada como carreadora dos géis sobre a área a ser avaliada (hemiarco inferior esquerdo). Os sujeitos foram aleatoriamente designados para usar o gel placebo (grupo controle) ou o gel teste (grupo experimental), sendo instruídos a colocar o gel na moldeira e esta sobre os dentes teste, escovando os outros normalmente três vezes ao dia. No dia 0 e dia 21 os índices de placa visível (IPV) e índice de sangramento gengival (ISG) foram registrados. RESULTADOS: Os resultados não demonstraram diferença estatística significante entre os grupos controle e experimental para nenhum dos índices. CONCLUSÕES: O gel contendo extrato de romã a 10% não foi eficiente em evitar a formação de placa bacteriana supragengival e prevenir a inflamação gengival. Universidade de São Paulo. Faculdade de Odontologia de Bauru2006-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/336210.1590/S1678-77572006000300003Journal of Applied Oral Science; Vol. 14 No. 3 (2006); 162-166 Journal of Applied Oral Science; Vol. 14 Núm. 3 (2006); 162-166 Journal of Applied Oral Science; v. 14 n. 3 (2006); 162-166 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3362/4052Copyright (c) 2006 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessSalgado, Alexandre Daher YunesMaia, Juliana LemosPereira, Sérgio Luís da SilvaLemos, Telma Leda Gomes deMota, Olívia Morais de Lima2012-04-27T11:53:47Zoai:revistas.usp.br:article/3362Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T11:53:47Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans Efeito antiplaca e antiinflamatório de um gel contendo extrato de romã: estudo clínico duplo-cego em humanos |
title |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans |
spellingShingle |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans Salgado, Alexandre Daher Yunes Placa bacteriana Gengivite Punica granatum Linn Dental plaque Gingivitis Punica granatum Linn |
title_short |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans |
title_full |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans |
title_fullStr |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans |
title_full_unstemmed |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans |
title_sort |
Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans |
author |
Salgado, Alexandre Daher Yunes |
author_facet |
Salgado, Alexandre Daher Yunes Maia, Juliana Lemos Pereira, Sérgio Luís da Silva Lemos, Telma Leda Gomes de Mota, Olívia Morais de Lima |
author_role |
author |
author2 |
Maia, Juliana Lemos Pereira, Sérgio Luís da Silva Lemos, Telma Leda Gomes de Mota, Olívia Morais de Lima |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Salgado, Alexandre Daher Yunes Maia, Juliana Lemos Pereira, Sérgio Luís da Silva Lemos, Telma Leda Gomes de Mota, Olívia Morais de Lima |
dc.subject.por.fl_str_mv |
Placa bacteriana Gengivite Punica granatum Linn Dental plaque Gingivitis Punica granatum Linn |
topic |
Placa bacteriana Gengivite Punica granatum Linn Dental plaque Gingivitis Punica granatum Linn |
description |
OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant). The subjects were randomly assigned to use either the placebo gel (control group) or the test gel (experimental group) and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI) and gingival bleeding index (GBI) were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI). CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3362 10.1590/S1678-77572006000300003 |
url |
https://www.revistas.usp.br/jaos/article/view/3362 |
identifier_str_mv |
10.1590/S1678-77572006000300003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3362/4052 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2006 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2006 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 14 No. 3 (2006); 162-166 Journal of Applied Oral Science; Vol. 14 Núm. 3 (2006); 162-166 Journal of Applied Oral Science; v. 14 n. 3 (2006); 162-166 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221672731574272 |