Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers

Detalhes bibliográficos
Autor(a) principal: Veloso,Heloisa Helena Pinho
Data de Publicação: 2006
Outros Autores: Santos,Roberto Alves do, Araújo,Túlio Pessoa de, Leonardi,Denise Piotto, Baratto Filho,Flares
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of applied oral science (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572006000500014
Resumo: OBJECTIVE: To histologically evaluate the behavior of the subcutaneous tissue of rats after placement of polyethylene tubes filled with calcium hydroxide-based root canal sealers (SealapexTM, ApexitTM e Sealer 26TM). STUDY DESIGN: The study employed 60 rats, which were divided into eight groups, being four experimental groups with 10 rats each, and four control groups with five rats. Analysis was conducted at 48 hours, 7, 21 and 60 days. RESULTS: Histological analysis revealed that all sealers were irritant; however, the intensity varied between each sealer and as a function of time. At the initial periods (48 hours and seven days), all materials demonstrated similar outcomes, with inflammatory reaction from severe to moderate, respectively. At the final periods (21 and 60 days), the tissue reactions to the implants containing SealapexTM displayed an active status yet with regression, compared to the ApexitTM and Sealer 26TM. The control groups exhibited less inflammatory cells than the experimental groups, keeping a reaction status with regression. CONCLUSIONS: The results achieved in this study revealed that the SealapexTM sealer was the most compatible, followed by ApexitTM and Sealer 26TM.
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spelling Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealersBiocompatible materialsRoot canal obturationCalcium hydroxideOBJECTIVE: To histologically evaluate the behavior of the subcutaneous tissue of rats after placement of polyethylene tubes filled with calcium hydroxide-based root canal sealers (SealapexTM, ApexitTM e Sealer 26TM). STUDY DESIGN: The study employed 60 rats, which were divided into eight groups, being four experimental groups with 10 rats each, and four control groups with five rats. Analysis was conducted at 48 hours, 7, 21 and 60 days. RESULTS: Histological analysis revealed that all sealers were irritant; however, the intensity varied between each sealer and as a function of time. At the initial periods (48 hours and seven days), all materials demonstrated similar outcomes, with inflammatory reaction from severe to moderate, respectively. At the final periods (21 and 60 days), the tissue reactions to the implants containing SealapexTM displayed an active status yet with regression, compared to the ApexitTM and Sealer 26TM. The control groups exhibited less inflammatory cells than the experimental groups, keeping a reaction status with regression. CONCLUSIONS: The results achieved in this study revealed that the SealapexTM sealer was the most compatible, followed by ApexitTM and Sealer 26TM.Faculdade De Odontologia De Bauru - USP2006-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572006000500014Journal of Applied Oral Science v.14 n.5 2006reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/S1678-77572006000500014info:eu-repo/semantics/openAccessVeloso,Heloisa Helena PinhoSantos,Roberto Alves doAraújo,Túlio Pessoa deLeonardi,Denise PiottoBaratto Filho,Flareseng2007-01-09T00:00:00Zoai:scielo:S1678-77572006000500014Revistahttp://www.scielo.br/jaosPUBhttps://old.scielo.br/oai/scielo-oai.php||jaos@usp.br1678-77651678-7757opendoar:2007-01-09T00:00Journal of applied oral science (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
title Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
spellingShingle Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
Veloso,Heloisa Helena Pinho
Biocompatible materials
Root canal obturation
Calcium hydroxide
title_short Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
title_full Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
title_fullStr Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
title_full_unstemmed Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
title_sort Histological analysis of the biocompatibility of three different calcium hydroxide-based root canal sealers
author Veloso,Heloisa Helena Pinho
author_facet Veloso,Heloisa Helena Pinho
Santos,Roberto Alves do
Araújo,Túlio Pessoa de
Leonardi,Denise Piotto
Baratto Filho,Flares
author_role author
author2 Santos,Roberto Alves do
Araújo,Túlio Pessoa de
Leonardi,Denise Piotto
Baratto Filho,Flares
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Veloso,Heloisa Helena Pinho
Santos,Roberto Alves do
Araújo,Túlio Pessoa de
Leonardi,Denise Piotto
Baratto Filho,Flares
dc.subject.por.fl_str_mv Biocompatible materials
Root canal obturation
Calcium hydroxide
topic Biocompatible materials
Root canal obturation
Calcium hydroxide
description OBJECTIVE: To histologically evaluate the behavior of the subcutaneous tissue of rats after placement of polyethylene tubes filled with calcium hydroxide-based root canal sealers (SealapexTM, ApexitTM e Sealer 26TM). STUDY DESIGN: The study employed 60 rats, which were divided into eight groups, being four experimental groups with 10 rats each, and four control groups with five rats. Analysis was conducted at 48 hours, 7, 21 and 60 days. RESULTS: Histological analysis revealed that all sealers were irritant; however, the intensity varied between each sealer and as a function of time. At the initial periods (48 hours and seven days), all materials demonstrated similar outcomes, with inflammatory reaction from severe to moderate, respectively. At the final periods (21 and 60 days), the tissue reactions to the implants containing SealapexTM displayed an active status yet with regression, compared to the ApexitTM and Sealer 26TM. The control groups exhibited less inflammatory cells than the experimental groups, keeping a reaction status with regression. CONCLUSIONS: The results achieved in this study revealed that the SealapexTM sealer was the most compatible, followed by ApexitTM and Sealer 26TM.
publishDate 2006
dc.date.none.fl_str_mv 2006-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572006000500014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572006000500014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1678-77572006000500014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
publisher.none.fl_str_mv Faculdade De Odontologia De Bauru - USP
dc.source.none.fl_str_mv Journal of Applied Oral Science v.14 n.5 2006
reponame:Journal of applied oral science (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Journal of applied oral science (Online)
collection Journal of applied oral science (Online)
repository.name.fl_str_mv Journal of applied oral science (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||jaos@usp.br
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