Risk Factors Associated with Postoperative Infection in Cancer Patients Undergoing Spine Surgery

• Autor(a) principal: Tavares-Júnior, Mauro Costa Morais
• Data de Publicação: 2021
• Outros Autores: Cabrera, Gabriela Estefania Delgado, Teixeira, William Gemio Jacobsen, Narazaki, Douglas Kenji, Ghilardi, Cesar Salge, Marcon, Raphael Martus, Cristante, Alexandre Fogaça, Barros-Filho, Tarcisio Eloy Pessoa de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Clinics
• Texto Completo: https://www.revistas.usp.br/clinics/article/view/191949
• topic: Surgical Site Infection; Spine Tumor; Risk Factors; Postoperative Complication; Spinal Metastasis

OBJECTIVES: To determine the rate of and main risk factors for postoperative infection in cancer patients who underwent spine surgery in the last 5 years in order to determine whether there is an association between postoperative infection and increased mortality during hospitalization. METHODS: All cancer patients who underwent surgical procedures between January 2015 and December 2019 at a single hospital specializing in spine cancer surgery were analyzed. The primary outcome of interest was postoperative infection. Bivariate logistic regression was used to estimate the odds ratio and 95% confidence interval for each variable in relation to the occurrence of infection. RESULTS: We evaluated 324 patients, including 176 men (54.3%) and 148 women (45.7%) with a mean age of 56 years. The incidence of postoperative infection was 20.37%. Of the 324 patients, 39 died during hospitalization (12%). CONCLUSIONS: Surgical time greater than 4 hours, surgical instrumented levels greater than 6, and an Eastern Cooperative Oncology Group of 3 or 4 were associated with an increased risk of postoperative infection, but these factors did not lead to an increase in mortality during hospitalization.