Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension

Detalhes bibliográficos
Autor(a) principal: Rocha, Aloísio Marchi
Data de Publicação: 2009
Outros Autores: Salemi, Vera Maria Cury, Lemos Neto, Pedro Alves, Matsumoto, Afonso Yoshikiro, Pereira, Valéria Fontenelle Angelim, Fernandes, Fábio, Nastari, Luciano, Mady, Charles
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/18016
Resumo: OBJECTIVES: We evaluated the impairment of endothelium-dependent and endothelium-independent coronary blood flow reserve after administration of intracoronary acetylcholine and adenosine, and its association with hypertensive cardiac disease. INTRODUCTION: Coronary blood flow reserve reduction has been proposed as a mechanism for the progression of compensated left ventricular hypertrophy to ventricular dysfunction. METHODS: Eighteen hypertensive patients with normal epicardial coronary arteries on angiography were divided into two groups according to left ventricular fractional shortening (FS). Group 1 (FS >;0.25): n=8, FS=0.29 ± 0.03; Group 2 (FS
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spelling Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension Coronary blood flow reserveHypertensionHeart failureAdenosineAcetylcholine OBJECTIVES: We evaluated the impairment of endothelium-dependent and endothelium-independent coronary blood flow reserve after administration of intracoronary acetylcholine and adenosine, and its association with hypertensive cardiac disease. INTRODUCTION: Coronary blood flow reserve reduction has been proposed as a mechanism for the progression of compensated left ventricular hypertrophy to ventricular dysfunction. METHODS: Eighteen hypertensive patients with normal epicardial coronary arteries on angiography were divided into two groups according to left ventricular fractional shortening (FS). Group 1 (FS >;0.25): n=8, FS=0.29 ± 0.03; Group 2 (FS Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2009-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1801610.1590/S1807-59322009000400011Clinics; Vol. 64 No. 4 (2009); 327-335 Clinics; v. 64 n. 4 (2009); 327-335 Clinics; Vol. 64 Núm. 4 (2009); 327-335 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/18016/20081Rocha, Aloísio MarchiSalemi, Vera Maria CuryLemos Neto, Pedro AlvesMatsumoto, Afonso YoshikiroPereira, Valéria Fontenelle AngelimFernandes, FábioNastari, LucianoMady, Charlesinfo:eu-repo/semantics/openAccess2012-05-22T18:51:28Zoai:revistas.usp.br:article/18016Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:51:28Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
title Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
spellingShingle Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
Rocha, Aloísio Marchi
Coronary blood flow reserve
Hypertension
Heart failure
Adenosine
Acetylcholine
title_short Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
title_full Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
title_fullStr Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
title_full_unstemmed Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
title_sort Endothelial and non-endothelial coronary blood flow reserve and left ventricular dysfunction in systemic hypertension
author Rocha, Aloísio Marchi
author_facet Rocha, Aloísio Marchi
Salemi, Vera Maria Cury
Lemos Neto, Pedro Alves
Matsumoto, Afonso Yoshikiro
Pereira, Valéria Fontenelle Angelim
Fernandes, Fábio
Nastari, Luciano
Mady, Charles
author_role author
author2 Salemi, Vera Maria Cury
Lemos Neto, Pedro Alves
Matsumoto, Afonso Yoshikiro
Pereira, Valéria Fontenelle Angelim
Fernandes, Fábio
Nastari, Luciano
Mady, Charles
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rocha, Aloísio Marchi
Salemi, Vera Maria Cury
Lemos Neto, Pedro Alves
Matsumoto, Afonso Yoshikiro
Pereira, Valéria Fontenelle Angelim
Fernandes, Fábio
Nastari, Luciano
Mady, Charles
dc.subject.por.fl_str_mv Coronary blood flow reserve
Hypertension
Heart failure
Adenosine
Acetylcholine
topic Coronary blood flow reserve
Hypertension
Heart failure
Adenosine
Acetylcholine
description OBJECTIVES: We evaluated the impairment of endothelium-dependent and endothelium-independent coronary blood flow reserve after administration of intracoronary acetylcholine and adenosine, and its association with hypertensive cardiac disease. INTRODUCTION: Coronary blood flow reserve reduction has been proposed as a mechanism for the progression of compensated left ventricular hypertrophy to ventricular dysfunction. METHODS: Eighteen hypertensive patients with normal epicardial coronary arteries on angiography were divided into two groups according to left ventricular fractional shortening (FS). Group 1 (FS >;0.25): n=8, FS=0.29 ± 0.03; Group 2 (FS
publishDate 2009
dc.date.none.fl_str_mv 2009-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/18016
10.1590/S1807-59322009000400011
url https://www.revistas.usp.br/clinics/article/view/18016
identifier_str_mv 10.1590/S1807-59322009000400011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/18016/20081
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 64 No. 4 (2009); 327-335
Clinics; v. 64 n. 4 (2009); 327-335
Clinics; Vol. 64 Núm. 4 (2009); 327-335
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
_version_ 1800222754724642816

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