Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease

Detalhes bibliográficos
Autor(a) principal: Araújo, Cristiana Marques de
Data de Publicação: 2009
Outros Autores: Solimene, Maria Cecilia, Grupi, Cesar Jose, Genta, Pedro Rodrigues, Lorenzi-Filho, Geraldo, Luz, Protásio Lemos Da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/17998
Resumo: There is controversy regarding whether obstructive sleep apnea is responsible for triggering myocardial ischemia, arrhythmias and heart rate variability in patients with coronary artery disease. OBJETIVE: The objective of this study was to identify relationships between sleep apnea, myocardial ischemia and cardiac arrhythmia in patients with coronary artery disease. METHODS: Fifty-three patients with stable coronary disease underwent simultaneous polysomnography and electrocardiographic Holter recording. The apnea-hypopnea index (AHI) was defined as the number of apneas/hypopneas per hour of sleep. Patients were divided into a Control group (AHI15, n=23 pts) and an Apnea group (AHI>;15, n=30 pts). A subgroup of 13 patients with an AHI>;30 (Severe Apnea group) was also studied. We analyzed ischemic episodes (ST-segment depressions >;1 mm, >; 1 min), heart rate variability and the occurrence of arrhythmias during wakefulness and sleep. RESULTS: Baseline clinical characteristics among the groups were similar except for higher blood pressure in the Apnea groups (p
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spelling Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease Sleep apneaMyocardial ischemiaHeart rate variabilityArrhythmias There is controversy regarding whether obstructive sleep apnea is responsible for triggering myocardial ischemia, arrhythmias and heart rate variability in patients with coronary artery disease. OBJETIVE: The objective of this study was to identify relationships between sleep apnea, myocardial ischemia and cardiac arrhythmia in patients with coronary artery disease. METHODS: Fifty-three patients with stable coronary disease underwent simultaneous polysomnography and electrocardiographic Holter recording. The apnea-hypopnea index (AHI) was defined as the number of apneas/hypopneas per hour of sleep. Patients were divided into a Control group (AHI15, n=23 pts) and an Apnea group (AHI>;15, n=30 pts). A subgroup of 13 patients with an AHI>;30 (Severe Apnea group) was also studied. We analyzed ischemic episodes (ST-segment depressions >;1 mm, >; 1 min), heart rate variability and the occurrence of arrhythmias during wakefulness and sleep. RESULTS: Baseline clinical characteristics among the groups were similar except for higher blood pressure in the Apnea groups (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2009-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1799810.1590/S1807-59322009000300013Clinics; Vol. 64 No. 3 (2009); 223-230 Clinics; v. 64 n. 3 (2009); 223-230 Clinics; Vol. 64 Núm. 3 (2009); 223-230 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/17998/20063Araújo, Cristiana Marques deSolimene, Maria CeciliaGrupi, Cesar JoseGenta, Pedro RodriguesLorenzi-Filho, GeraldoLuz, Protásio Lemos Dainfo:eu-repo/semantics/openAccess2012-05-22T18:50:26Zoai:revistas.usp.br:article/17998Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:50:26Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
title Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
spellingShingle Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
Araújo, Cristiana Marques de
Sleep apnea
Myocardial ischemia
Heart rate variability
Arrhythmias
title_short Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
title_full Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
title_fullStr Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
title_full_unstemmed Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
title_sort Evidence that the degree of obstructive sleep apnea may not increase myocardial ischemia and arrhythmias in patients with stable coronary artery disease
author Araújo, Cristiana Marques de
author_facet Araújo, Cristiana Marques de
Solimene, Maria Cecilia
Grupi, Cesar Jose
Genta, Pedro Rodrigues
Lorenzi-Filho, Geraldo
Luz, Protásio Lemos Da
author_role author
author2 Solimene, Maria Cecilia
Grupi, Cesar Jose
Genta, Pedro Rodrigues
Lorenzi-Filho, Geraldo
Luz, Protásio Lemos Da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Cristiana Marques de
Solimene, Maria Cecilia
Grupi, Cesar Jose
Genta, Pedro Rodrigues
Lorenzi-Filho, Geraldo
Luz, Protásio Lemos Da
dc.subject.por.fl_str_mv Sleep apnea
Myocardial ischemia
Heart rate variability
Arrhythmias
topic Sleep apnea
Myocardial ischemia
Heart rate variability
Arrhythmias
description There is controversy regarding whether obstructive sleep apnea is responsible for triggering myocardial ischemia, arrhythmias and heart rate variability in patients with coronary artery disease. OBJETIVE: The objective of this study was to identify relationships between sleep apnea, myocardial ischemia and cardiac arrhythmia in patients with coronary artery disease. METHODS: Fifty-three patients with stable coronary disease underwent simultaneous polysomnography and electrocardiographic Holter recording. The apnea-hypopnea index (AHI) was defined as the number of apneas/hypopneas per hour of sleep. Patients were divided into a Control group (AHI15, n=23 pts) and an Apnea group (AHI>;15, n=30 pts). A subgroup of 13 patients with an AHI>;30 (Severe Apnea group) was also studied. We analyzed ischemic episodes (ST-segment depressions >;1 mm, >; 1 min), heart rate variability and the occurrence of arrhythmias during wakefulness and sleep. RESULTS: Baseline clinical characteristics among the groups were similar except for higher blood pressure in the Apnea groups (p
publishDate 2009
dc.date.none.fl_str_mv 2009-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/17998
10.1590/S1807-59322009000300013
url https://www.revistas.usp.br/clinics/article/view/17998
identifier_str_mv 10.1590/S1807-59322009000300013
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/17998/20063
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 64 No. 3 (2009); 223-230
Clinics; v. 64 n. 3 (2009); 223-230
Clinics; Vol. 64 Núm. 3 (2009); 223-230
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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