Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/83752 |
Resumo: | OBJECTIVES: This study aimed to investigate the clinical correlation between angiographic coronary atherosclerosis and N-terminal pro-B-type natriuretic peptide along with other known correlated factors. METHODS: In total, 153 patients with a diagnostic hypothesis of stable angina, unstable angina or acute myocardial infarction were classified as group A (patients with angiographically normal coronary arteries) or group B (patients with angiographic coronary atherosclerosis). The two groups were analyzed with respect to the following factors: gender, age, body mass index, abdominal circumference, smoking, diabetes mellitus, arterial hypertension, early family history of atherosclerosis, statin use, the presence of metabolic syndrome, clinical presentation and biochemical factors, including cholesterol, creatinine and fibrinogen plasma concentrations, monocyte counts and N-terminal pro-B-type natriuretic peptide. RESULTS: Univariate analyses comparing the two groups revealed that group B patients more frequently had diabetes, used statins and had systolic dysfunction, N-terminal pro-B-type natriuretic peptide levels ≥250 pg/mL, fibrinogen levels >;500 mg/dL and ≥501 monocytes/mm3 compared with group A patients (p |
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Clinics |
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Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis OBJECTIVES: This study aimed to investigate the clinical correlation between angiographic coronary atherosclerosis and N-terminal pro-B-type natriuretic peptide along with other known correlated factors. METHODS: In total, 153 patients with a diagnostic hypothesis of stable angina, unstable angina or acute myocardial infarction were classified as group A (patients with angiographically normal coronary arteries) or group B (patients with angiographic coronary atherosclerosis). The two groups were analyzed with respect to the following factors: gender, age, body mass index, abdominal circumference, smoking, diabetes mellitus, arterial hypertension, early family history of atherosclerosis, statin use, the presence of metabolic syndrome, clinical presentation and biochemical factors, including cholesterol, creatinine and fibrinogen plasma concentrations, monocyte counts and N-terminal pro-B-type natriuretic peptide. RESULTS: Univariate analyses comparing the two groups revealed that group B patients more frequently had diabetes, used statins and had systolic dysfunction, N-terminal pro-B-type natriuretic peptide levels ≥250 pg/mL, fibrinogen levels >;500 mg/dL and ≥501 monocytes/mm3 compared with group A patients (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2014-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/8375210.6061/clinics/2014(06)07Clinics; Vol. 69 No. 6 (2014); 405-412Clinics; v. 69 n. 6 (2014); 405-412Clinics; Vol. 69 Núm. 6 (2014); 405-4121980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/83752/86656Ribeiro, Demóstenes G.L. Silva, Ricardo P. Barboza, Daniella R.M.M. Lima-Júnior, Roberto C.P. Ribeiro, Ronaldo A. info:eu-repo/semantics/openAccess2014-08-12T22:31:56Zoai:revistas.usp.br:article/83752Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2014-08-12T22:31:56Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
title |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
spellingShingle |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis Ribeiro, Demóstenes G.L. |
title_short |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
title_full |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
title_fullStr |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
title_full_unstemmed |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
title_sort |
Clinical correlation between N-terminal pro-b-type natriuretic peptide and angiographic coronary atherosclerosis |
author |
Ribeiro, Demóstenes G.L. |
author_facet |
Ribeiro, Demóstenes G.L. Silva, Ricardo P. Barboza, Daniella R.M.M. Lima-Júnior, Roberto C.P. Ribeiro, Ronaldo A. |
author_role |
author |
author2 |
Silva, Ricardo P. Barboza, Daniella R.M.M. Lima-Júnior, Roberto C.P. Ribeiro, Ronaldo A. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ribeiro, Demóstenes G.L. Silva, Ricardo P. Barboza, Daniella R.M.M. Lima-Júnior, Roberto C.P. Ribeiro, Ronaldo A. |
description |
OBJECTIVES: This study aimed to investigate the clinical correlation between angiographic coronary atherosclerosis and N-terminal pro-B-type natriuretic peptide along with other known correlated factors. METHODS: In total, 153 patients with a diagnostic hypothesis of stable angina, unstable angina or acute myocardial infarction were classified as group A (patients with angiographically normal coronary arteries) or group B (patients with angiographic coronary atherosclerosis). The two groups were analyzed with respect to the following factors: gender, age, body mass index, abdominal circumference, smoking, diabetes mellitus, arterial hypertension, early family history of atherosclerosis, statin use, the presence of metabolic syndrome, clinical presentation and biochemical factors, including cholesterol, creatinine and fibrinogen plasma concentrations, monocyte counts and N-terminal pro-B-type natriuretic peptide. RESULTS: Univariate analyses comparing the two groups revealed that group B patients more frequently had diabetes, used statins and had systolic dysfunction, N-terminal pro-B-type natriuretic peptide levels ≥250 pg/mL, fibrinogen levels >;500 mg/dL and ≥501 monocytes/mm3 compared with group A patients (p |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/83752 10.6061/clinics/2014(06)07 |
url |
https://www.revistas.usp.br/clinics/article/view/83752 |
identifier_str_mv |
10.6061/clinics/2014(06)07 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/83752/86656 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 69 No. 6 (2014); 405-412 Clinics; v. 69 n. 6 (2014); 405-412 Clinics; Vol. 69 Núm. 6 (2014); 405-412 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222761210085376 |