Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/107678 |
Resumo: | OBJECTIVES: Perfusion abnormalities are frequently seen in Single Photon Emission Computed Tomography (SPECT) when a left bundle branch block is present. A few studies have shown decreased coronary flow reserve in the left anterior descending territory, regardless of the presence of coronary artery disease. OBJECTIVE: We sought to investigate rubidium-82 (82Rb) positron emission tomography imaging in the assessment of myocardial blood flow and coronary flow reserve in patients with left bundle branch block. METHODS: Thirty-eight patients with left bundle branch block (GI), median age 63.5 years, 22 (58%) female, 12 with coronary artery disease (≥70%; GI-A) and 26 with no evidence of significant coronary artery disease (GI-B), underwent rest-dipyridamole stress 82Rb-positron emission tomography with absolute quantitative flow measurements using Cedars-Sinai software (mL/min/g). The relative myocardial perfusion and left ventricular ejection fraction were assessed in 17 segments. These parameters were compared with those obtained from 30 patients with normal 82Rb-positron emission tomography studies and without left bundle branch block (GII). RESULTS: Stress myocardial blood flow and coronary flow reserve were significantly lower in GI than in GII (p |
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oai:revistas.usp.br:article/107678 |
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Clinics |
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Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block OBJECTIVES: Perfusion abnormalities are frequently seen in Single Photon Emission Computed Tomography (SPECT) when a left bundle branch block is present. A few studies have shown decreased coronary flow reserve in the left anterior descending territory, regardless of the presence of coronary artery disease. OBJECTIVE: We sought to investigate rubidium-82 (82Rb) positron emission tomography imaging in the assessment of myocardial blood flow and coronary flow reserve in patients with left bundle branch block. METHODS: Thirty-eight patients with left bundle branch block (GI), median age 63.5 years, 22 (58%) female, 12 with coronary artery disease (≥70%; GI-A) and 26 with no evidence of significant coronary artery disease (GI-B), underwent rest-dipyridamole stress 82Rb-positron emission tomography with absolute quantitative flow measurements using Cedars-Sinai software (mL/min/g). The relative myocardial perfusion and left ventricular ejection fraction were assessed in 17 segments. These parameters were compared with those obtained from 30 patients with normal 82Rb-positron emission tomography studies and without left bundle branch block (GII). RESULTS: Stress myocardial blood flow and coronary flow reserve were significantly lower in GI than in GII (pHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2015-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/10767810.6061/clinics/2015(11)02Clinics; Vol. 70 No. 11 (2015); 726-732Clinics; v. 70 n. 11 (2015); 726-732Clinics; Vol. 70 Núm. 11 (2015); 726-7321980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/107678/106058Copyright (c) 2015 Clinicsinfo:eu-repo/semantics/openAccessFalcão, AndréaChalela, WilliamGiorgi, Maria ClementinaImada, RodrigoSoares Jr, JoséDo Val, RenataOliveira, Marco AntonioIzaki, MarisaKalil Filho, Roberto KalilMeneghetti, José C.2015-11-24T12:09:34Zoai:revistas.usp.br:article/107678Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2015-11-24T12:09:34Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
title |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
spellingShingle |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block Falcão, Andréa |
title_short |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
title_full |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
title_fullStr |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
title_full_unstemmed |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
title_sort |
Myocardial blood flow assessment with 82rubidium-PET imaging in patients with left bundle branch block |
author |
Falcão, Andréa |
author_facet |
Falcão, Andréa Chalela, William Giorgi, Maria Clementina Imada, Rodrigo Soares Jr, José Do Val, Renata Oliveira, Marco Antonio Izaki, Marisa Kalil Filho, Roberto Kalil Meneghetti, José C. |
author_role |
author |
author2 |
Chalela, William Giorgi, Maria Clementina Imada, Rodrigo Soares Jr, José Do Val, Renata Oliveira, Marco Antonio Izaki, Marisa Kalil Filho, Roberto Kalil Meneghetti, José C. |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Falcão, Andréa Chalela, William Giorgi, Maria Clementina Imada, Rodrigo Soares Jr, José Do Val, Renata Oliveira, Marco Antonio Izaki, Marisa Kalil Filho, Roberto Kalil Meneghetti, José C. |
description |
OBJECTIVES: Perfusion abnormalities are frequently seen in Single Photon Emission Computed Tomography (SPECT) when a left bundle branch block is present. A few studies have shown decreased coronary flow reserve in the left anterior descending territory, regardless of the presence of coronary artery disease. OBJECTIVE: We sought to investigate rubidium-82 (82Rb) positron emission tomography imaging in the assessment of myocardial blood flow and coronary flow reserve in patients with left bundle branch block. METHODS: Thirty-eight patients with left bundle branch block (GI), median age 63.5 years, 22 (58%) female, 12 with coronary artery disease (≥70%; GI-A) and 26 with no evidence of significant coronary artery disease (GI-B), underwent rest-dipyridamole stress 82Rb-positron emission tomography with absolute quantitative flow measurements using Cedars-Sinai software (mL/min/g). The relative myocardial perfusion and left ventricular ejection fraction were assessed in 17 segments. These parameters were compared with those obtained from 30 patients with normal 82Rb-positron emission tomography studies and without left bundle branch block (GII). RESULTS: Stress myocardial blood flow and coronary flow reserve were significantly lower in GI than in GII (p |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-11-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/107678 10.6061/clinics/2015(11)02 |
url |
https://www.revistas.usp.br/clinics/article/view/107678 |
identifier_str_mv |
10.6061/clinics/2015(11)02 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/107678/106058 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2015 Clinics info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2015 Clinics |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 70 No. 11 (2015); 726-732 Clinics; v. 70 n. 11 (2015); 726-732 Clinics; Vol. 70 Núm. 11 (2015); 726-732 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222762247127040 |