Therapeutic approaches for spinal cord injury

Detalhes bibliográficos
Autor(a) principal: Cristante, Alexandre Fogaça
Data de Publicação: 2012
Outros Autores: Barros Filho, Tarcísio Eloy Pessoa de, Marcon, Raphael Martus, Letaif, Olavo Biraghi, Rocha, Ivan Dias da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/47937
Resumo: This study reviews the literature concerning possible therapeutic approaches for spinal cord injury. Spinal cord injury is a disabling and irreversible condition that has high economic and social costs. There are both primary and secondary mechanisms of damage to the spinal cord. The primary lesion is the mechanical injury itself. The secondary lesion results from one or more biochemical and cellular processes that are triggered by the primary lesion. The frustration of health professionals in treating a severe spinal cord injury was described in 1700 BC in an Egyptian surgical papyrus that was translated by Edwin Smith; the papyrus reported spinal fractures as a ''disease that should not be treated.'' Over the last biological or pharmacological treatment method. Science is unraveling the mechanisms of cell protection and neuroregeneration, but clinically, we only provide supportive care for patients with spinal cord injuries. By combining these treatments, researchers attempt to enhance the functional recovery of patients with spinal cord injuries. Advances in the last decade have allowed us to encourage the development of experimental studies in the field of spinal cord regeneration. The combination of several therapeutic strategies should, at minimum, allow for partial functional recoveries for these patients, which could improve their quality of life.
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spelling Therapeutic approaches for spinal cord injurySpinal Cord InjuriesRehabilitationCentral Nervous System^i1^sInjurThis study reviews the literature concerning possible therapeutic approaches for spinal cord injury. Spinal cord injury is a disabling and irreversible condition that has high economic and social costs. There are both primary and secondary mechanisms of damage to the spinal cord. The primary lesion is the mechanical injury itself. The secondary lesion results from one or more biochemical and cellular processes that are triggered by the primary lesion. The frustration of health professionals in treating a severe spinal cord injury was described in 1700 BC in an Egyptian surgical papyrus that was translated by Edwin Smith; the papyrus reported spinal fractures as a ''disease that should not be treated.'' Over the last biological or pharmacological treatment method. Science is unraveling the mechanisms of cell protection and neuroregeneration, but clinically, we only provide supportive care for patients with spinal cord injuries. By combining these treatments, researchers attempt to enhance the functional recovery of patients with spinal cord injuries. Advances in the last decade have allowed us to encourage the development of experimental studies in the field of spinal cord regeneration. The combination of several therapeutic strategies should, at minimum, allow for partial functional recoveries for these patients, which could improve their quality of life.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2012-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/4793710.6061/clinics/2012(10)16Clinics; Vol. 67 No. 10 (2012); 1219-1224Clinics; v. 67 n. 10 (2012); 1219-1224Clinics; Vol. 67 Núm. 10 (2012); 1219-12241980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/47937/51677Cristante, Alexandre FogaçaBarros Filho, Tarcísio Eloy Pessoa deMarcon, Raphael MartusLetaif, Olavo BiraghiRocha, Ivan Dias dainfo:eu-repo/semantics/openAccess2012-12-13T11:01:19Zoai:revistas.usp.br:article/47937Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-12-13T11:01:19Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Therapeutic approaches for spinal cord injury
title Therapeutic approaches for spinal cord injury
spellingShingle Therapeutic approaches for spinal cord injury
Cristante, Alexandre Fogaça
Spinal Cord Injuries
Rehabilitation
Central Nervous System^i1^sInjur
title_short Therapeutic approaches for spinal cord injury
title_full Therapeutic approaches for spinal cord injury
title_fullStr Therapeutic approaches for spinal cord injury
title_full_unstemmed Therapeutic approaches for spinal cord injury
title_sort Therapeutic approaches for spinal cord injury
author Cristante, Alexandre Fogaça
author_facet Cristante, Alexandre Fogaça
Barros Filho, Tarcísio Eloy Pessoa de
Marcon, Raphael Martus
Letaif, Olavo Biraghi
Rocha, Ivan Dias da
author_role author
author2 Barros Filho, Tarcísio Eloy Pessoa de
Marcon, Raphael Martus
Letaif, Olavo Biraghi
Rocha, Ivan Dias da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Cristante, Alexandre Fogaça
Barros Filho, Tarcísio Eloy Pessoa de
Marcon, Raphael Martus
Letaif, Olavo Biraghi
Rocha, Ivan Dias da
dc.subject.por.fl_str_mv Spinal Cord Injuries
Rehabilitation
Central Nervous System^i1^sInjur
topic Spinal Cord Injuries
Rehabilitation
Central Nervous System^i1^sInjur
description This study reviews the literature concerning possible therapeutic approaches for spinal cord injury. Spinal cord injury is a disabling and irreversible condition that has high economic and social costs. There are both primary and secondary mechanisms of damage to the spinal cord. The primary lesion is the mechanical injury itself. The secondary lesion results from one or more biochemical and cellular processes that are triggered by the primary lesion. The frustration of health professionals in treating a severe spinal cord injury was described in 1700 BC in an Egyptian surgical papyrus that was translated by Edwin Smith; the papyrus reported spinal fractures as a ''disease that should not be treated.'' Over the last biological or pharmacological treatment method. Science is unraveling the mechanisms of cell protection and neuroregeneration, but clinically, we only provide supportive care for patients with spinal cord injuries. By combining these treatments, researchers attempt to enhance the functional recovery of patients with spinal cord injuries. Advances in the last decade have allowed us to encourage the development of experimental studies in the field of spinal cord regeneration. The combination of several therapeutic strategies should, at minimum, allow for partial functional recoveries for these patients, which could improve their quality of life.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/47937
10.6061/clinics/2012(10)16
url https://www.revistas.usp.br/clinics/article/view/47937
identifier_str_mv 10.6061/clinics/2012(10)16
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/47937/51677
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 67 No. 10 (2012); 1219-1224
Clinics; v. 67 n. 10 (2012); 1219-1224
Clinics; Vol. 67 Núm. 10 (2012); 1219-1224
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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