Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/17825 |
Resumo: | INTRODUCTION: It is known that mechanical ventilation and many of its features may affect the evolution of inspiratory muscle strength during ventilation. However, this evolution has not been described, nor have its predictors been studied. In addition, a probable parallel between inspiratory and limb muscle strength evolution has not been investigated. OBJECTIVE: To describe the variation over time of maximal inspiratory pressure during mechanical ventilation and its predictors. We also studied the possible relationship between the evolution of maximal inspiratory pressure and limb muscle strength. METHODS: A prospective observational study was performed in consecutive patients submitted to mechanical ventilation for >; 72 hours. The maximal inspiratory pressure trend was evaluated by the linear regression of the daily maximal inspiratory pressure and a logistic regression analysis was used to look for independent maximal inspiratory pressure trend predictors. Limb muscle strength was evaluated using the Medical Research Council score. RESULTS: One hundred and sixteen patients were studied, forty-four of whom (37.9%) presented a decrease in maximal inspiratory pressure over time. The members of the group in which maximal inspiratory pressure decreased underwent deeper sedation, spent less time in pressure support ventilation and were extubated less frequently. The only independent predictor of the maximal inspiratory pressure trend was the level of sedation (OR=1.55, 95% CI 1.003 - 2.408; p = 0.049). There was no relationship between the maximal inspiratory pressure trend and limb muscle strength. CONCLUSIONS: Around forty percent of the mechanically ventilated patients had a decreased maximal inspiratory pressure during mechanical ventilation, which was independently associated with deeper levels of sedation. There was no relationship between the evolution of maximal inspiratory pressure and the muscular strength of the limb. |
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Clinics |
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Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors Respiratory MuscleMechanical VentilationRisk FactorMuscular ParesisSide Effects INTRODUCTION: It is known that mechanical ventilation and many of its features may affect the evolution of inspiratory muscle strength during ventilation. However, this evolution has not been described, nor have its predictors been studied. In addition, a probable parallel between inspiratory and limb muscle strength evolution has not been investigated. OBJECTIVE: To describe the variation over time of maximal inspiratory pressure during mechanical ventilation and its predictors. We also studied the possible relationship between the evolution of maximal inspiratory pressure and limb muscle strength. METHODS: A prospective observational study was performed in consecutive patients submitted to mechanical ventilation for >; 72 hours. The maximal inspiratory pressure trend was evaluated by the linear regression of the daily maximal inspiratory pressure and a logistic regression analysis was used to look for independent maximal inspiratory pressure trend predictors. Limb muscle strength was evaluated using the Medical Research Council score. RESULTS: One hundred and sixteen patients were studied, forty-four of whom (37.9%) presented a decrease in maximal inspiratory pressure over time. The members of the group in which maximal inspiratory pressure decreased underwent deeper sedation, spent less time in pressure support ventilation and were extubated less frequently. The only independent predictor of the maximal inspiratory pressure trend was the level of sedation (OR=1.55, 95% CI 1.003 - 2.408; p = 0.049). There was no relationship between the maximal inspiratory pressure trend and limb muscle strength. CONCLUSIONS: Around forty percent of the mechanically ventilated patients had a decreased maximal inspiratory pressure during mechanical ventilation, which was independently associated with deeper levels of sedation. There was no relationship between the evolution of maximal inspiratory pressure and the muscular strength of the limb. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1782510.1590/S1807-59322008000100007Clinics; Vol. 63 No. 1 (2008); 33-38 Clinics; v. 63 n. 1 (2008); 33-38 Clinics; Vol. 63 Núm. 1 (2008); 33-38 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/17825/19890Caruso, PedroCarnieli, Denise SimãoKagohara, Keila HarueAnciães, AdrianaSegarra, Jacqueline SantosDeheinzelin, Danielinfo:eu-repo/semantics/openAccess2012-05-22T18:36:29Zoai:revistas.usp.br:article/17825Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T18:36:29Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
title |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
spellingShingle |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors Caruso, Pedro Respiratory Muscle Mechanical Ventilation Risk Factor Muscular Paresis Side Effects |
title_short |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
title_full |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
title_fullStr |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
title_full_unstemmed |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
title_sort |
Trend of maximal inspiratory pressure in mechanically ventilated patients: predictors |
author |
Caruso, Pedro |
author_facet |
Caruso, Pedro Carnieli, Denise Simão Kagohara, Keila Harue Anciães, Adriana Segarra, Jacqueline Santos Deheinzelin, Daniel |
author_role |
author |
author2 |
Carnieli, Denise Simão Kagohara, Keila Harue Anciães, Adriana Segarra, Jacqueline Santos Deheinzelin, Daniel |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Caruso, Pedro Carnieli, Denise Simão Kagohara, Keila Harue Anciães, Adriana Segarra, Jacqueline Santos Deheinzelin, Daniel |
dc.subject.por.fl_str_mv |
Respiratory Muscle Mechanical Ventilation Risk Factor Muscular Paresis Side Effects |
topic |
Respiratory Muscle Mechanical Ventilation Risk Factor Muscular Paresis Side Effects |
description |
INTRODUCTION: It is known that mechanical ventilation and many of its features may affect the evolution of inspiratory muscle strength during ventilation. However, this evolution has not been described, nor have its predictors been studied. In addition, a probable parallel between inspiratory and limb muscle strength evolution has not been investigated. OBJECTIVE: To describe the variation over time of maximal inspiratory pressure during mechanical ventilation and its predictors. We also studied the possible relationship between the evolution of maximal inspiratory pressure and limb muscle strength. METHODS: A prospective observational study was performed in consecutive patients submitted to mechanical ventilation for >; 72 hours. The maximal inspiratory pressure trend was evaluated by the linear regression of the daily maximal inspiratory pressure and a logistic regression analysis was used to look for independent maximal inspiratory pressure trend predictors. Limb muscle strength was evaluated using the Medical Research Council score. RESULTS: One hundred and sixteen patients were studied, forty-four of whom (37.9%) presented a decrease in maximal inspiratory pressure over time. The members of the group in which maximal inspiratory pressure decreased underwent deeper sedation, spent less time in pressure support ventilation and were extubated less frequently. The only independent predictor of the maximal inspiratory pressure trend was the level of sedation (OR=1.55, 95% CI 1.003 - 2.408; p = 0.049). There was no relationship between the maximal inspiratory pressure trend and limb muscle strength. CONCLUSIONS: Around forty percent of the mechanically ventilated patients had a decreased maximal inspiratory pressure during mechanical ventilation, which was independently associated with deeper levels of sedation. There was no relationship between the evolution of maximal inspiratory pressure and the muscular strength of the limb. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/17825 10.1590/S1807-59322008000100007 |
url |
https://www.revistas.usp.br/clinics/article/view/17825 |
identifier_str_mv |
10.1590/S1807-59322008000100007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/17825/19890 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; Vol. 63 No. 1 (2008); 33-38 Clinics; v. 63 n. 1 (2008); 33-38 Clinics; Vol. 63 Núm. 1 (2008); 33-38 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1800222753926676480 |