High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study

Detalhes bibliográficos
Autor(a) principal: Penteado, Fernando Travaglini
Data de Publicação: 2011
Outros Autores: Faloppa, Flávio, Giusti, Guilherme, Moraes, Vinícius Ynoe, Belloti, João Carlos, Santos, João Baptista Gomes dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/19432
Resumo: OBJECTIVE: The aim of this study was to analyze the effect of high-energy extracorporeal shockwave therapy on tendon angiogenesis in the patellar tendons of rabbits. We sought to investigate whether different voltage and number pulses modify the angiogenesis pattern. INTRODUCTION: High-energy extracorporeal shockwave therapy is an option in the treatment of orthopedic diseases such as chronic tendonitis. Despite its potential clinical applicability, there have been few studies on this technique that examine both its clinical effectiveness and its effect on angiogenesis. METHODS: High-energy extracorporeal shockwave therapy was applied at the tibial insertion of the left patellar ligament in 30 rabbits that were separated into six groups that differed in terms of the voltage and number of pulses that were applied by high-energy extracorporeal shockwave therapy. The tibial insertion in the right legs of the animals was used as the control. After six weeks, we performed histological analysis on the region and quantified the number of blood vessels. RESULTS: No significant differences in the number of blood vessels between the left and right patellar tendons were found within groups. Additionally, no significant differences in the number of blood vessels in the left patellar tendons were found between groups. CONCLUSIONS: The application of high-energy extracorporeal shockwave therapy did not cause a change in vascularization in the patellar tendon in rabbits.
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spelling High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study High-energy shock wavesPatellar ligamentNeovascularizationAnimal model OBJECTIVE: The aim of this study was to analyze the effect of high-energy extracorporeal shockwave therapy on tendon angiogenesis in the patellar tendons of rabbits. We sought to investigate whether different voltage and number pulses modify the angiogenesis pattern. INTRODUCTION: High-energy extracorporeal shockwave therapy is an option in the treatment of orthopedic diseases such as chronic tendonitis. Despite its potential clinical applicability, there have been few studies on this technique that examine both its clinical effectiveness and its effect on angiogenesis. METHODS: High-energy extracorporeal shockwave therapy was applied at the tibial insertion of the left patellar ligament in 30 rabbits that were separated into six groups that differed in terms of the voltage and number of pulses that were applied by high-energy extracorporeal shockwave therapy. The tibial insertion in the right legs of the animals was used as the control. After six weeks, we performed histological analysis on the region and quantified the number of blood vessels. RESULTS: No significant differences in the number of blood vessels between the left and right patellar tendons were found within groups. Additionally, no significant differences in the number of blood vessels in the left patellar tendons were found between groups. CONCLUSIONS: The application of high-energy extracorporeal shockwave therapy did not cause a change in vascularization in the patellar tendon in rabbits. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2011-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1943210.1590/S1807-59322011000900018Clinics; Vol. 66 No. 9 (2011); 1611-1614 Clinics; v. 66 n. 9 (2011); 1611-1614 Clinics; Vol. 66 Núm. 9 (2011); 1611-1614 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/19432/21495Penteado, Fernando TravagliniFaloppa, FlávioGiusti, GuilhermeMoraes, Vinícius YnoeBelloti, João CarlosSantos, João Baptista Gomes dosinfo:eu-repo/semantics/openAccess2012-05-23T16:40:38Zoai:revistas.usp.br:article/19432Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-23T16:40:38Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
title High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
spellingShingle High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
Penteado, Fernando Travaglini
High-energy shock waves
Patellar ligament
Neovascularization
Animal model
title_short High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
title_full High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
title_fullStr High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
title_full_unstemmed High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
title_sort High-energy extracorporeal shockwave therapy in a patellar tendon animal model: a vascularizationfocused study
author Penteado, Fernando Travaglini
author_facet Penteado, Fernando Travaglini
Faloppa, Flávio
Giusti, Guilherme
Moraes, Vinícius Ynoe
Belloti, João Carlos
Santos, João Baptista Gomes dos
author_role author
author2 Faloppa, Flávio
Giusti, Guilherme
Moraes, Vinícius Ynoe
Belloti, João Carlos
Santos, João Baptista Gomes dos
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Penteado, Fernando Travaglini
Faloppa, Flávio
Giusti, Guilherme
Moraes, Vinícius Ynoe
Belloti, João Carlos
Santos, João Baptista Gomes dos
dc.subject.por.fl_str_mv High-energy shock waves
Patellar ligament
Neovascularization
Animal model
topic High-energy shock waves
Patellar ligament
Neovascularization
Animal model
description OBJECTIVE: The aim of this study was to analyze the effect of high-energy extracorporeal shockwave therapy on tendon angiogenesis in the patellar tendons of rabbits. We sought to investigate whether different voltage and number pulses modify the angiogenesis pattern. INTRODUCTION: High-energy extracorporeal shockwave therapy is an option in the treatment of orthopedic diseases such as chronic tendonitis. Despite its potential clinical applicability, there have been few studies on this technique that examine both its clinical effectiveness and its effect on angiogenesis. METHODS: High-energy extracorporeal shockwave therapy was applied at the tibial insertion of the left patellar ligament in 30 rabbits that were separated into six groups that differed in terms of the voltage and number of pulses that were applied by high-energy extracorporeal shockwave therapy. The tibial insertion in the right legs of the animals was used as the control. After six weeks, we performed histological analysis on the region and quantified the number of blood vessels. RESULTS: No significant differences in the number of blood vessels between the left and right patellar tendons were found within groups. Additionally, no significant differences in the number of blood vessels in the left patellar tendons were found between groups. CONCLUSIONS: The application of high-energy extracorporeal shockwave therapy did not cause a change in vascularization in the patellar tendon in rabbits.
publishDate 2011
dc.date.none.fl_str_mv 2011-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/19432
10.1590/S1807-59322011000900018
url https://www.revistas.usp.br/clinics/article/view/19432
identifier_str_mv 10.1590/S1807-59322011000900018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/19432/21495
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 66 No. 9 (2011); 1611-1614
Clinics; v. 66 n. 9 (2011); 1611-1614
Clinics; Vol. 66 Núm. 9 (2011); 1611-1614
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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