Diagnostic ability of barrett's index to detect dysthyroid optic neuropathy using multidetector computed tomography

• Autor(a) principal: Monteiro, Mário L. R.
• Data de Publicação: 2008
• Outros Autores: Gonçalves, Allan C. P., Silva, Carla T. M., Moura, Janete P., Ribeiro, Carolina S., Gebrim, Eloisa M.M.S.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Clinics
• Texto Completo: https://www.revistas.usp.br/clinics/article/view/17797
• topic: Dysthyroid Optic Neuropathy; Multidetector computed tomography; Graves' Orbitopathy; Visual loss; Thyroid eye disease

OBJECTIVES: The objective of this study was to evaluate the ability of a muscular index (Barrett's Index), calculated with multidetector computed tomography, to detect dysthyroid optic neuropathy in patients with Graves' orbitopathy. METHODS: Thirty-six patients with Graves' orbitopathy were prospectively studied and submitted to neuro-ophthalmic evaluation and multidetector computed tomography scans of the orbits. Orbits were divided into two groups: those with and without dysthyroid optic neuropathy. Barrett's index was calculated as the percentage of the orbit occupied by muscles. Sensitivity and specificity were determined for several index values. RESULTS: Sixty-four orbits (19 with and 45 without dysthyroid optic neuropathy) met the inclusion criteria for the study. The mean Barrett's index values (± SD) were 64.47% ± 6.06% and 49.44% ± 10.94%in the groups with and without dysthyroid optic neuropathy, respectively (p;60% should be carefully examined and followed for the development of dysthyroid optic neuropathy.