Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography

Detalhes bibliográficos
Autor(a) principal: Papa, Eduardo D.E.
Data de Publicação: 2013
Outros Autores: Helber, Izo, Ehrlichmann, Manes R., Alves, Claudia Maria Rodrigues, Makdisse, Marcia, Matos, Livia N., Borges, Jairo Lins, Lopes, Renato D., Stefanini, Edson, Carvalho, Antonio Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/77284
Resumo: OBJECTIVES: To correlate the importance of the ankle-brachial index in terms of cardiovascular morbimortalityand the extent of coronary arterial disease amongst elderly patients without clinical manifestations of lowerlimb peripheral arterial disease.METHODS: We analyzed prospective data from 100 patients over 65 years of age with coronary arterial disease,as confirmed by coronary angiography, and with over 70% stenosis of at least one sub-epicardial coronaryartery. We measured the ankle-brachial index immediately after coronary angiography, and a value of ,0.9was used to diagnose peripheral arterial disease.RESULTS: The patients’ average age was 77.4 years. The most prevalent risk factor was hypertension (96%), andthe median late follow-up appointment was 28.9 months. The ankle-brachial index was ,0.9 in 47% of thepatients, and a low index was more prevalent in patients with multiarterial coronary disease compared topatients with uniarterial disease in the same group. Using a bivariate analysis, only an ankle-brachial index of,0.9 was a strong predictive factor for cardiovascular events, thereby increasing all-cause deaths and fatal andnon-fatal acute myocardial infarctions two- to three-fold.CONCLUSION: In elderly patients with documented coronary disease, a low ankle-brachial index (,0.9) wasassociated with the severity and extent of coronary arterial disease, and in late follow-up appointments, a lowindex was correlated with an increase in the occurrence of major cardiovascular events.
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spelling Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiographyPeripheral Artery DiseasePrognosisCoronary artery DiseaseAnkle Brachial IndexElderlyOBJECTIVES: To correlate the importance of the ankle-brachial index in terms of cardiovascular morbimortalityand the extent of coronary arterial disease amongst elderly patients without clinical manifestations of lowerlimb peripheral arterial disease.METHODS: We analyzed prospective data from 100 patients over 65 years of age with coronary arterial disease,as confirmed by coronary angiography, and with over 70% stenosis of at least one sub-epicardial coronaryartery. We measured the ankle-brachial index immediately after coronary angiography, and a value of ,0.9was used to diagnose peripheral arterial disease.RESULTS: The patients’ average age was 77.4 years. The most prevalent risk factor was hypertension (96%), andthe median late follow-up appointment was 28.9 months. The ankle-brachial index was ,0.9 in 47% of thepatients, and a low index was more prevalent in patients with multiarterial coronary disease compared topatients with uniarterial disease in the same group. Using a bivariate analysis, only an ankle-brachial index of,0.9 was a strong predictive factor for cardiovascular events, thereby increasing all-cause deaths and fatal andnon-fatal acute myocardial infarctions two- to three-fold.CONCLUSION: In elderly patients with documented coronary disease, a low ankle-brachial index (,0.9) wasassociated with the severity and extent of coronary arterial disease, and in late follow-up appointments, a lowindex was correlated with an increase in the occurrence of major cardiovascular events.Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2013-12-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/7728410.1590/clin.v68i12.77284Clinics; Vol. 68 No. 12 (2013); 1481-1487Clinics; v. 68 n. 12 (2013); 1481-1487Clinics; Vol. 68 Núm. 12 (2013); 1481-14871980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/77284/81152Papa, Eduardo D.E.Helber, IzoEhrlichmann, Manes R.Alves, Claudia Maria RodriguesMakdisse, MarciaMatos, Livia N.Borges, Jairo LinsLopes, Renato D.Stefanini, EdsonCarvalho, Antonio Carlosinfo:eu-repo/semantics/openAccess2015-06-16T11:28:21Zoai:revistas.usp.br:article/77284Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2015-06-16T11:28:21Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
title Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
spellingShingle Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
Papa, Eduardo D.E.
Peripheral Artery Disease
Prognosis
Coronary artery Disease
Ankle Brachial Index
Elderly
title_short Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
title_full Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
title_fullStr Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
title_full_unstemmed Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
title_sort Ankle-brachial index as a predictor of coronary disease events in elderly patients submitted to coronary angiography
author Papa, Eduardo D.E.
author_facet Papa, Eduardo D.E.
Helber, Izo
Ehrlichmann, Manes R.
Alves, Claudia Maria Rodrigues
Makdisse, Marcia
Matos, Livia N.
Borges, Jairo Lins
Lopes, Renato D.
Stefanini, Edson
Carvalho, Antonio Carlos
author_role author
author2 Helber, Izo
Ehrlichmann, Manes R.
Alves, Claudia Maria Rodrigues
Makdisse, Marcia
Matos, Livia N.
Borges, Jairo Lins
Lopes, Renato D.
Stefanini, Edson
Carvalho, Antonio Carlos
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Papa, Eduardo D.E.
Helber, Izo
Ehrlichmann, Manes R.
Alves, Claudia Maria Rodrigues
Makdisse, Marcia
Matos, Livia N.
Borges, Jairo Lins
Lopes, Renato D.
Stefanini, Edson
Carvalho, Antonio Carlos
dc.subject.por.fl_str_mv Peripheral Artery Disease
Prognosis
Coronary artery Disease
Ankle Brachial Index
Elderly
topic Peripheral Artery Disease
Prognosis
Coronary artery Disease
Ankle Brachial Index
Elderly
description OBJECTIVES: To correlate the importance of the ankle-brachial index in terms of cardiovascular morbimortalityand the extent of coronary arterial disease amongst elderly patients without clinical manifestations of lowerlimb peripheral arterial disease.METHODS: We analyzed prospective data from 100 patients over 65 years of age with coronary arterial disease,as confirmed by coronary angiography, and with over 70% stenosis of at least one sub-epicardial coronaryartery. We measured the ankle-brachial index immediately after coronary angiography, and a value of ,0.9was used to diagnose peripheral arterial disease.RESULTS: The patients’ average age was 77.4 years. The most prevalent risk factor was hypertension (96%), andthe median late follow-up appointment was 28.9 months. The ankle-brachial index was ,0.9 in 47% of thepatients, and a low index was more prevalent in patients with multiarterial coronary disease compared topatients with uniarterial disease in the same group. Using a bivariate analysis, only an ankle-brachial index of,0.9 was a strong predictive factor for cardiovascular events, thereby increasing all-cause deaths and fatal andnon-fatal acute myocardial infarctions two- to three-fold.CONCLUSION: In elderly patients with documented coronary disease, a low ankle-brachial index (,0.9) wasassociated with the severity and extent of coronary arterial disease, and in late follow-up appointments, a lowindex was correlated with an increase in the occurrence of major cardiovascular events.
publishDate 2013
dc.date.none.fl_str_mv 2013-12-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/77284
10.1590/clin.v68i12.77284
url https://www.revistas.usp.br/clinics/article/view/77284
identifier_str_mv 10.1590/clin.v68i12.77284
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/77284/81152
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; Vol. 68 No. 12 (2013); 1481-1487
Clinics; v. 68 n. 12 (2013); 1481-1487
Clinics; Vol. 68 Núm. 12 (2013); 1481-1487
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||clinics@hc.fm.usp.br
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