Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil

Detalhes bibliográficos
Autor(a) principal: Fedeli, Ligia G
Data de Publicação: 2013
Outros Autores: Vidigal, Pedro G, Leite, Claudia Mendes, Castilhos, Cristina D, Pimentel, Robercia Anjos, Maniero, Viviane C, Mill, Jose Geraldo, Lotufo, Paulo A, Pereira, Alexandre C, Bensenor, Isabela M
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/76736
Resumo: The ELSA (Estudo Longitudinal de Saúde do Adulto - Brazilian Longitudinal Study for Adult Health) is a multicenter cohort study which aims at the identification of risk factors associated with type 2 diabetes and cardiovascular diseases in the Brazilian population. The paper describes the strategies for the collection, processing, transportation, and quality control of blood and urine tests in the ELSA. The study decided to centralize the tests at one single laboratory. The processing of the samples was performed at the local laboratories, reducing the weight of the material to be transported, and diminishing the costs of transportation to the central laboratory at the Universidade de São Paulo Hospital. The study included tests for the evaluation of diabetes, insulin resistance, dyslipidemia, electrolyte abnormalities, thyroid hormones, uric acid, hepatic enzyme abnormalities, inflammation, and total blood cell count. In addition, leukocyte DNA, urine, plasma and serum samples were stored. The central laboratory performed approximately 375,000 tests.
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spelling Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-BrasilLogistica de coleta e transporte de material biologico e organizacao do laboratorio central no ELSA-BrasilThe ELSA (Estudo Longitudinal de Saúde do Adulto - Brazilian Longitudinal Study for Adult Health) is a multicenter cohort study which aims at the identification of risk factors associated with type 2 diabetes and cardiovascular diseases in the Brazilian population. The paper describes the strategies for the collection, processing, transportation, and quality control of blood and urine tests in the ELSA. The study decided to centralize the tests at one single laboratory. The processing of the samples was performed at the local laboratories, reducing the weight of the material to be transported, and diminishing the costs of transportation to the central laboratory at the Universidade de São Paulo Hospital. The study included tests for the evaluation of diabetes, insulin resistance, dyslipidemia, electrolyte abnormalities, thyroid hormones, uric acid, hepatic enzyme abnormalities, inflammation, and total blood cell count. In addition, leukocyte DNA, urine, plasma and serum samples were stored. The central laboratory performed approximately 375,000 tests.O Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) é um estudo de coorte multicêntrico com o objetivo de identificar os fatores de risco associados ao diabetes tipo 2 e à doença cardiovascular na população brasileira. O artigo descreve as estratégias de coleta, processamento, transporte e de controle de qualidade dos exames de sangue e urina no ELSA. O estudo optou pela centralização dos exames em um único laboratório. O processamento das amostras foi realizado nos laboratórios locais, reduzindo o peso do material a ser transportado e diminuindo os custos do transporte para o laboratório central no Hospital da Universidade de São Paulo. O estudo incluiu exames para avaliação de diabetes, resistência à insulina, dislipidemias, alterações eletrolíticas, hormônios tireoidianos, ácido úrico, alterações de enzimas hepáticas, inflamação e hemograma completo. Além desses exames, foram estocados DNA de leucócitos, amostras de urina, plasma e soro. O laboratório central realizou aproximadamente 375.000 exames.Universidade de São Paulo. Faculdade de Saúde Pública2013-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/7673610.1590/rsp.v47isuppl.2.76736Revista de Saúde Pública; Vol. 47 No. suppl. 2 (2013); 63-71Revista de Saúde Pública; Vol. 47 Núm. suppl. 2 (2013); 63-71Revista de Saúde Pública; v. 47 n. suppl. 2 (2013); 63-711518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporenghttps://www.revistas.usp.br/rsp/article/view/76736/80573https://www.revistas.usp.br/rsp/article/view/76736/80574Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessFedeli, Ligia GVidigal, Pedro GLeite, Claudia MendesCastilhos, Cristina DPimentel, Robercia AnjosManiero, Viviane CMill, Jose GeraldoLotufo, Paulo APereira, Alexandre CBensenor, Isabela M2014-03-21T12:02:34Zoai:revistas.usp.br:article/76736Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2014-03-21T12:02:34Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
Logistica de coleta e transporte de material biologico e organizacao do laboratorio central no ELSA-Brasil
title Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
spellingShingle Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
Fedeli, Ligia G
title_short Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
title_full Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
title_fullStr Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
title_full_unstemmed Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
title_sort Logistics of collection and transportation of biological samples and the organization of the central laboratory in the ELSA-Brasil
author Fedeli, Ligia G
author_facet Fedeli, Ligia G
Vidigal, Pedro G
Leite, Claudia Mendes
Castilhos, Cristina D
Pimentel, Robercia Anjos
Maniero, Viviane C
Mill, Jose Geraldo
Lotufo, Paulo A
Pereira, Alexandre C
Bensenor, Isabela M
author_role author
author2 Vidigal, Pedro G
Leite, Claudia Mendes
Castilhos, Cristina D
Pimentel, Robercia Anjos
Maniero, Viviane C
Mill, Jose Geraldo
Lotufo, Paulo A
Pereira, Alexandre C
Bensenor, Isabela M
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fedeli, Ligia G
Vidigal, Pedro G
Leite, Claudia Mendes
Castilhos, Cristina D
Pimentel, Robercia Anjos
Maniero, Viviane C
Mill, Jose Geraldo
Lotufo, Paulo A
Pereira, Alexandre C
Bensenor, Isabela M
description The ELSA (Estudo Longitudinal de Saúde do Adulto - Brazilian Longitudinal Study for Adult Health) is a multicenter cohort study which aims at the identification of risk factors associated with type 2 diabetes and cardiovascular diseases in the Brazilian population. The paper describes the strategies for the collection, processing, transportation, and quality control of blood and urine tests in the ELSA. The study decided to centralize the tests at one single laboratory. The processing of the samples was performed at the local laboratories, reducing the weight of the material to be transported, and diminishing the costs of transportation to the central laboratory at the Universidade de São Paulo Hospital. The study included tests for the evaluation of diabetes, insulin resistance, dyslipidemia, electrolyte abnormalities, thyroid hormones, uric acid, hepatic enzyme abnormalities, inflammation, and total blood cell count. In addition, leukocyte DNA, urine, plasma and serum samples were stored. The central laboratory performed approximately 375,000 tests.
publishDate 2013
dc.date.none.fl_str_mv 2013-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/76736
10.1590/rsp.v47isuppl.2.76736
url https://www.revistas.usp.br/rsp/article/view/76736
identifier_str_mv 10.1590/rsp.v47isuppl.2.76736
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/76736/80573
https://www.revistas.usp.br/rsp/article/view/76736/80574
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 47 No. suppl. 2 (2013); 63-71
Revista de Saúde Pública; Vol. 47 Núm. suppl. 2 (2013); 63-71
Revista de Saúde Pública; v. 47 n. suppl. 2 (2013); 63-71
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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