Iron salt supplementation during gestation and gestational diabetes mellitus

Detalhes bibliográficos
Autor(a) principal: Miranda, Vanessa Iribarrem Avena
Data de Publicação: 2023
Outros Autores: Pizzol, Tatiane da Silva Dal, Silveira, Marysabel Pinto Telis, Mengue, Sotero Serrate, Silveira, Mariângela Freitas da, Lutz, Bárbara Heather, Bertoldi, Andréa Dâmaso
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/219139
Resumo: OBJETIVE: To evaluate the association between the use of iron salts during the first two trimesters of gestation in non-anemic women and the development of gestational diabetes mellitus. METHODS: The study used maternal data from the 2015 Pelotas Birth Cohort. All non-anemic women at the 24th week of gestation (n = 2,463) were eligible for this study. Gestational diabetes mellitus was self-reported by women. Crude and adjusted logistic regression were performed considering level of significance = 0.05. RESULTS: Among the women studied, 69.7% were exposed to prophylactic iron supplementation in the first two trimesters of gestation. The prevalence of gestational diabetes mellitus among those exposed was 8.7% (95%CI: 7.4–10.1) and 9.3% (95%CI: 7.4–11.6) among those who were not exposed. Iron supplementation was not associated with increased risk of gestational diabetes mellitus in crude (OR = 0.9; 95%CI: 0,7–1,3) and adjusted analysis (OR = 1.1; 95%CI :0,8–1,6). CONCLUSIONS: The results suggest that routine iron use in non-anemic pregnant women does not increase the risk of developing gestational diabetes. This evidence supports the existing national and international guidelines, in which prophylactic iron supplementation is recommended for all pregnant women as soon as they initiate antenatal care in order to prevent iron deficiency anemia.
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spelling Iron salt supplementation during gestation and gestational diabetes mellitusPharmacoepidemiologyDrug UtilizationCohort StudiesDiabetes, GestationalOBJETIVE: To evaluate the association between the use of iron salts during the first two trimesters of gestation in non-anemic women and the development of gestational diabetes mellitus. METHODS: The study used maternal data from the 2015 Pelotas Birth Cohort. All non-anemic women at the 24th week of gestation (n = 2,463) were eligible for this study. Gestational diabetes mellitus was self-reported by women. Crude and adjusted logistic regression were performed considering level of significance = 0.05. RESULTS: Among the women studied, 69.7% were exposed to prophylactic iron supplementation in the first two trimesters of gestation. The prevalence of gestational diabetes mellitus among those exposed was 8.7% (95%CI: 7.4–10.1) and 9.3% (95%CI: 7.4–11.6) among those who were not exposed. Iron supplementation was not associated with increased risk of gestational diabetes mellitus in crude (OR = 0.9; 95%CI: 0,7–1,3) and adjusted analysis (OR = 1.1; 95%CI :0,8–1,6). CONCLUSIONS: The results suggest that routine iron use in non-anemic pregnant women does not increase the risk of developing gestational diabetes. This evidence supports the existing national and international guidelines, in which prophylactic iron supplementation is recommended for all pregnant women as soon as they initiate antenatal care in order to prevent iron deficiency anemia.Universidade de São Paulo. Faculdade de Saúde Pública2023-09-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/xmlhttps://www.revistas.usp.br/rsp/article/view/21913910.11606/s1518-8787.2023057004871Revista de Saúde Pública; Vol. 57 No. 1 (2023); 71Revista de Saúde Pública; Vol. 57 Núm. 1 (2023); 71Revista de Saúde Pública; v. 57 n. 1 (2023); 711518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/rsp/article/view/219139/200063https://www.revistas.usp.br/rsp/article/view/219139/200062Copyright (c) 2023 Vanessa Iribarrem Avena Miranda, Tatiane da Silva Dal Pizzol, Marysabel Pinto Telis Silveira, Sotero Serrate Mengue, Mariângela Freitas da Silveira, Bárbara Heather Lutz, Andréa Dâmaso Bertoldihttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMiranda, Vanessa Iribarrem AvenaPizzol, Tatiane da Silva DalSilveira, Marysabel Pinto TelisMengue, Sotero SerrateSilveira, Mariângela Freitas daLutz, Bárbara HeatherBertoldi, Andréa Dâmaso2023-11-22T20:42:47Zoai:revistas.usp.br:article/219139Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2023-11-22T20:42:47Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Iron salt supplementation during gestation and gestational diabetes mellitus
title Iron salt supplementation during gestation and gestational diabetes mellitus
spellingShingle Iron salt supplementation during gestation and gestational diabetes mellitus
Miranda, Vanessa Iribarrem Avena
Pharmacoepidemiology
Drug Utilization
Cohort Studies
Diabetes, Gestational
title_short Iron salt supplementation during gestation and gestational diabetes mellitus
title_full Iron salt supplementation during gestation and gestational diabetes mellitus
title_fullStr Iron salt supplementation during gestation and gestational diabetes mellitus
title_full_unstemmed Iron salt supplementation during gestation and gestational diabetes mellitus
title_sort Iron salt supplementation during gestation and gestational diabetes mellitus
author Miranda, Vanessa Iribarrem Avena
author_facet Miranda, Vanessa Iribarrem Avena
Pizzol, Tatiane da Silva Dal
Silveira, Marysabel Pinto Telis
Mengue, Sotero Serrate
Silveira, Mariângela Freitas da
Lutz, Bárbara Heather
Bertoldi, Andréa Dâmaso
author_role author
author2 Pizzol, Tatiane da Silva Dal
Silveira, Marysabel Pinto Telis
Mengue, Sotero Serrate
Silveira, Mariângela Freitas da
Lutz, Bárbara Heather
Bertoldi, Andréa Dâmaso
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Miranda, Vanessa Iribarrem Avena
Pizzol, Tatiane da Silva Dal
Silveira, Marysabel Pinto Telis
Mengue, Sotero Serrate
Silveira, Mariângela Freitas da
Lutz, Bárbara Heather
Bertoldi, Andréa Dâmaso
dc.subject.por.fl_str_mv Pharmacoepidemiology
Drug Utilization
Cohort Studies
Diabetes, Gestational
topic Pharmacoepidemiology
Drug Utilization
Cohort Studies
Diabetes, Gestational
description OBJETIVE: To evaluate the association between the use of iron salts during the first two trimesters of gestation in non-anemic women and the development of gestational diabetes mellitus. METHODS: The study used maternal data from the 2015 Pelotas Birth Cohort. All non-anemic women at the 24th week of gestation (n = 2,463) were eligible for this study. Gestational diabetes mellitus was self-reported by women. Crude and adjusted logistic regression were performed considering level of significance = 0.05. RESULTS: Among the women studied, 69.7% were exposed to prophylactic iron supplementation in the first two trimesters of gestation. The prevalence of gestational diabetes mellitus among those exposed was 8.7% (95%CI: 7.4–10.1) and 9.3% (95%CI: 7.4–11.6) among those who were not exposed. Iron supplementation was not associated with increased risk of gestational diabetes mellitus in crude (OR = 0.9; 95%CI: 0,7–1,3) and adjusted analysis (OR = 1.1; 95%CI :0,8–1,6). CONCLUSIONS: The results suggest that routine iron use in non-anemic pregnant women does not increase the risk of developing gestational diabetes. This evidence supports the existing national and international guidelines, in which prophylactic iron supplementation is recommended for all pregnant women as soon as they initiate antenatal care in order to prevent iron deficiency anemia.
publishDate 2023
dc.date.none.fl_str_mv 2023-09-29
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/219139
10.11606/s1518-8787.2023057004871
url https://www.revistas.usp.br/rsp/article/view/219139
identifier_str_mv 10.11606/s1518-8787.2023057004871
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/219139/200063
https://www.revistas.usp.br/rsp/article/view/219139/200062
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/xml
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 57 No. 1 (2023); 71
Revista de Saúde Pública; Vol. 57 Núm. 1 (2023); 71
Revista de Saúde Pública; v. 57 n. 1 (2023); 71
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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