Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up

Detalhes bibliográficos
Autor(a) principal: Machado, Soraia Mafra
Data de Publicação: 2017
Outros Autores: Almeida Neto, Cesar de, Pinho, João Renato Rebello, Malta, Fernanda de Mello, Capuani, Ligia, Campos, Aléia Faustina, Abreu, Fatima Regina Marques, Nastri, Ana Catharina de Seixas Santos, Santana, Rúbia Anita Ferraz, Sabino, Ester Cerdeira, Mendes-Correa, Maria Cássia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/132862
Resumo: OBJECTIVE To investigate the HCV cascade of care and to identify the factors associated with loss or absence to follow-up of patients identified as infected with hepatitis C through blood donation. METHODS Blood donors from 1994 to 2012, identified with positive anti- HCV by enzyme immunoassay and immunoblot tests were invited to participate in the study, through letters or phone calls. Patients who agreed to participate were interviewed and their blood samples were collected for further testing. The following variables were investigated: demographic data, data on comorbidities and history concerning monitoring of hepatitis C. Multiple regression analysis by Poisson regression model was used to investigate the factors associated with non-referral for consultation or loss of follow-up. RESULTS Of the 2,952 HCV-infected blood donors, 22.8% agreed to participate: 394 (58.2%) male, median age 48 years old and 364 (53.8%) Caucasian. Of the 676 participants, 39.7% did not receive proper follow-up or treatment after diagnosis: 45 patients referred not to be aware they were infected, 61 did not seek medical attention and 163 started a follow-up program, but were non-adherent. The main reasons for inadequate follow-up were not understanding the need for medical care (71%) and health care access difficulties (14%). The variables showing a significant association with inadequate follow-up after multiple regression analysis were male gender (PR = 1.40; 95%CI 1.15–1.71), age under or equal to 50 years (PR = 1.36; 95%CI 1.12–1.65) and non-Caucasians (PR = 1.53; 95%CI 1.27–1.84). CONCLUSIONS About 40.0% of patients did not receive appropriate follow-up. These data reinforce the need to establish strong links between primary care and reference centers and the need to improve access to specialists and treatments.
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spelling Hepatitis C among blood donors: cascade of care and predictors of loss to follow-upBlood DonorsHepatitis C diagnosisLost to Follow-UpRisk FactorsCascade of Care OBJECTIVE To investigate the HCV cascade of care and to identify the factors associated with loss or absence to follow-up of patients identified as infected with hepatitis C through blood donation. METHODS Blood donors from 1994 to 2012, identified with positive anti- HCV by enzyme immunoassay and immunoblot tests were invited to participate in the study, through letters or phone calls. Patients who agreed to participate were interviewed and their blood samples were collected for further testing. The following variables were investigated: demographic data, data on comorbidities and history concerning monitoring of hepatitis C. Multiple regression analysis by Poisson regression model was used to investigate the factors associated with non-referral for consultation or loss of follow-up. RESULTS Of the 2,952 HCV-infected blood donors, 22.8% agreed to participate: 394 (58.2%) male, median age 48 years old and 364 (53.8%) Caucasian. Of the 676 participants, 39.7% did not receive proper follow-up or treatment after diagnosis: 45 patients referred not to be aware they were infected, 61 did not seek medical attention and 163 started a follow-up program, but were non-adherent. The main reasons for inadequate follow-up were not understanding the need for medical care (71%) and health care access difficulties (14%). The variables showing a significant association with inadequate follow-up after multiple regression analysis were male gender (PR = 1.40; 95%CI 1.15–1.71), age under or equal to 50 years (PR = 1.36; 95%CI 1.12–1.65) and non-Caucasians (PR = 1.53; 95%CI 1.27–1.84). CONCLUSIONS About 40.0% of patients did not receive appropriate follow-up. These data reinforce the need to establish strong links between primary care and reference centers and the need to improve access to specialists and treatments.Universidade de São Paulo. Faculdade de Saúde Pública2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/13286210.1590/s1518-8787.2017051006468Revista de Saúde Pública; Vol. 51 (2017); 40Revista de Saúde Pública; Vol. 51 (2017); 40Revista de Saúde Pública; v. 51 (2017); 401518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/rsp/article/view/132862/128915Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessMachado, Soraia MafraAlmeida Neto, Cesar dePinho, João Renato RebelloMalta, Fernanda de MelloCapuani, LigiaCampos, Aléia FaustinaAbreu, Fatima Regina MarquesNastri, Ana Catharina de Seixas SantosSantana, Rúbia Anita FerrazSabino, Ester CerdeiraMendes-Correa, Maria Cássia2017-12-14T10:16:01Zoai:revistas.usp.br:article/132862Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2017-12-14T10:16:01Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
title Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
spellingShingle Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
Machado, Soraia Mafra
Blood Donors
Hepatitis C diagnosis
Lost to Follow-Up
Risk Factors
Cascade of Care
title_short Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
title_full Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
title_fullStr Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
title_full_unstemmed Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
title_sort Hepatitis C among blood donors: cascade of care and predictors of loss to follow-up
author Machado, Soraia Mafra
author_facet Machado, Soraia Mafra
Almeida Neto, Cesar de
Pinho, João Renato Rebello
Malta, Fernanda de Mello
Capuani, Ligia
Campos, Aléia Faustina
Abreu, Fatima Regina Marques
Nastri, Ana Catharina de Seixas Santos
Santana, Rúbia Anita Ferraz
Sabino, Ester Cerdeira
Mendes-Correa, Maria Cássia
author_role author
author2 Almeida Neto, Cesar de
Pinho, João Renato Rebello
Malta, Fernanda de Mello
Capuani, Ligia
Campos, Aléia Faustina
Abreu, Fatima Regina Marques
Nastri, Ana Catharina de Seixas Santos
Santana, Rúbia Anita Ferraz
Sabino, Ester Cerdeira
Mendes-Correa, Maria Cássia
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Machado, Soraia Mafra
Almeida Neto, Cesar de
Pinho, João Renato Rebello
Malta, Fernanda de Mello
Capuani, Ligia
Campos, Aléia Faustina
Abreu, Fatima Regina Marques
Nastri, Ana Catharina de Seixas Santos
Santana, Rúbia Anita Ferraz
Sabino, Ester Cerdeira
Mendes-Correa, Maria Cássia
dc.subject.por.fl_str_mv Blood Donors
Hepatitis C diagnosis
Lost to Follow-Up
Risk Factors
Cascade of Care
topic Blood Donors
Hepatitis C diagnosis
Lost to Follow-Up
Risk Factors
Cascade of Care
description OBJECTIVE To investigate the HCV cascade of care and to identify the factors associated with loss or absence to follow-up of patients identified as infected with hepatitis C through blood donation. METHODS Blood donors from 1994 to 2012, identified with positive anti- HCV by enzyme immunoassay and immunoblot tests were invited to participate in the study, through letters or phone calls. Patients who agreed to participate were interviewed and their blood samples were collected for further testing. The following variables were investigated: demographic data, data on comorbidities and history concerning monitoring of hepatitis C. Multiple regression analysis by Poisson regression model was used to investigate the factors associated with non-referral for consultation or loss of follow-up. RESULTS Of the 2,952 HCV-infected blood donors, 22.8% agreed to participate: 394 (58.2%) male, median age 48 years old and 364 (53.8%) Caucasian. Of the 676 participants, 39.7% did not receive proper follow-up or treatment after diagnosis: 45 patients referred not to be aware they were infected, 61 did not seek medical attention and 163 started a follow-up program, but were non-adherent. The main reasons for inadequate follow-up were not understanding the need for medical care (71%) and health care access difficulties (14%). The variables showing a significant association with inadequate follow-up after multiple regression analysis were male gender (PR = 1.40; 95%CI 1.15–1.71), age under or equal to 50 years (PR = 1.36; 95%CI 1.12–1.65) and non-Caucasians (PR = 1.53; 95%CI 1.27–1.84). CONCLUSIONS About 40.0% of patients did not receive appropriate follow-up. These data reinforce the need to establish strong links between primary care and reference centers and the need to improve access to specialists and treatments.
publishDate 2017
dc.date.none.fl_str_mv 2017-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/132862
10.1590/s1518-8787.2017051006468
url https://www.revistas.usp.br/rsp/article/view/132862
identifier_str_mv 10.1590/s1518-8787.2017051006468
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/132862/128915
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 51 (2017); 40
Revista de Saúde Pública; Vol. 51 (2017); 40
Revista de Saúde Pública; v. 51 (2017); 40
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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