Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children

Detalhes bibliográficos
Autor(a) principal: Rondó, Patrícia H C
Data de Publicação: 2006
Outros Autores: Carvalho, Maria de Fátima H, Souza, Miriam C, Moraes, Flávio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/31984
Resumo: OBJECTIVE: To assess the relationship of blood lead and hemoglobin, zinc protoporphyrin, and ferritin concentrations in children. METHODS: A cross-sectional study was carried out in 136 anemic and non-anemic children from two rural villages near a lead smelter in Adrianópolis, Southern Brazil, from July to September 2001. Hemoglobin electrophoresis was performed to exclude children with hemoglobin variants and thalassemia syndromes associated with anemia. Lead was determined by atomic absorption spectrophotometry; hemoglobin by automated cell counting; zinc protoporphyrin by hematofluorometry; ferritin by chemiluminescence. Student's t-test, Mann-Whitney test, and the c² test were used to assess the significance of the differences between the variables investigated in anemic and non-anemic children. Stepwise multivariate linear regression analysis was performed using two models for anemic and non-anemic children respectively. RESULTS: Lead was negatively associated to hemoglobin (p
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spelling Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children Concentrações de chumbo, hemoglobina, zinco protoporfirina e ferritina em crianças Intoxicação por chumboAnemiaHemoglobinaZincoProtoporfirinaFerritinaEstudos transversaisLead PoisoningAnemiaHemoglobinZincProtoporphyrinFerritinCross-sectional studies OBJECTIVE: To assess the relationship of blood lead and hemoglobin, zinc protoporphyrin, and ferritin concentrations in children. METHODS: A cross-sectional study was carried out in 136 anemic and non-anemic children from two rural villages near a lead smelter in Adrianópolis, Southern Brazil, from July to September 2001. Hemoglobin electrophoresis was performed to exclude children with hemoglobin variants and thalassemia syndromes associated with anemia. Lead was determined by atomic absorption spectrophotometry; hemoglobin by automated cell counting; zinc protoporphyrin by hematofluorometry; ferritin by chemiluminescence. Student's t-test, Mann-Whitney test, and the c² test were used to assess the significance of the differences between the variables investigated in anemic and non-anemic children. Stepwise multivariate linear regression analysis was performed using two models for anemic and non-anemic children respectively. RESULTS: Lead was negatively associated to hemoglobin (p OBJETIVO: Avaliar a relação entre as concentrações sangüíneas de chumbo, hemoglobina, zinco protoporfirina e ferritina em crianças. MÉTODOS: Estudo transversal realizado com 136 crianças anêmicas e não anêmicas residentes em duas vilas da região rural de Adrianópolis, Estado do Paraná, próximas a uma usina de beneficiamento de chumbo, de julho a setembro de 2001. A eletroforese de hemoglobina foi realizada para excluir as crianças com anemia associada a hemoglobinas variantes e síndromes talassêmicas. O chumbo foi determinado por meio de espectrofotometria de absorção atômica; a hemoglobina por contador celular automático; a zinco protoporfirina por hematofluorometria, e a ferritina por quimioluminescência. Os testes t de student, Mann-Whitney e chi2 foram utilizados para verificar a significância das diferenças entre as variáveis. Foi realizada uma análise de regressão linear multivariada stepwise, utilizando dois modelos, para crianças anêmicas e não anêmicas respectivamente. RESULTADOS: No primeiro modelo o chumbo estava negativamente associado com a hemoglobina (pUniversidade de São Paulo. Faculdade de Saúde Pública2006-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/3198410.1590/S0034-89102006000100012Revista de Saúde Pública; Vol. 40 No. 1 (2006); 71-76 Revista de Saúde Pública; Vol. 40 Núm. 1 (2006); 71-76 Revista de Saúde Pública; v. 40 n. 1 (2006); 71-76 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/rsp/article/view/31984/33995Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessRondó, Patrícia H CCarvalho, Maria de Fátima HSouza, Miriam CMoraes, Flávio2012-07-08T22:55:15Zoai:revistas.usp.br:article/31984Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-07-08T22:55:15Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
Concentrações de chumbo, hemoglobina, zinco protoporfirina e ferritina em crianças
title Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
spellingShingle Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
Rondó, Patrícia H C
Intoxicação por chumbo
Anemia
Hemoglobina
Zinco
Protoporfirina
Ferritina
Estudos transversais
Lead Poisoning
Anemia
Hemoglobin
Zinc
Protoporphyrin
Ferritin
Cross-sectional studies
title_short Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
title_full Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
title_fullStr Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
title_full_unstemmed Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
title_sort Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children
author Rondó, Patrícia H C
author_facet Rondó, Patrícia H C
Carvalho, Maria de Fátima H
Souza, Miriam C
Moraes, Flávio
author_role author
author2 Carvalho, Maria de Fátima H
Souza, Miriam C
Moraes, Flávio
author2_role author
author
author
dc.contributor.author.fl_str_mv Rondó, Patrícia H C
Carvalho, Maria de Fátima H
Souza, Miriam C
Moraes, Flávio
dc.subject.por.fl_str_mv Intoxicação por chumbo
Anemia
Hemoglobina
Zinco
Protoporfirina
Ferritina
Estudos transversais
Lead Poisoning
Anemia
Hemoglobin
Zinc
Protoporphyrin
Ferritin
Cross-sectional studies
topic Intoxicação por chumbo
Anemia
Hemoglobina
Zinco
Protoporfirina
Ferritina
Estudos transversais
Lead Poisoning
Anemia
Hemoglobin
Zinc
Protoporphyrin
Ferritin
Cross-sectional studies
description OBJECTIVE: To assess the relationship of blood lead and hemoglobin, zinc protoporphyrin, and ferritin concentrations in children. METHODS: A cross-sectional study was carried out in 136 anemic and non-anemic children from two rural villages near a lead smelter in Adrianópolis, Southern Brazil, from July to September 2001. Hemoglobin electrophoresis was performed to exclude children with hemoglobin variants and thalassemia syndromes associated with anemia. Lead was determined by atomic absorption spectrophotometry; hemoglobin by automated cell counting; zinc protoporphyrin by hematofluorometry; ferritin by chemiluminescence. Student's t-test, Mann-Whitney test, and the c² test were used to assess the significance of the differences between the variables investigated in anemic and non-anemic children. Stepwise multivariate linear regression analysis was performed using two models for anemic and non-anemic children respectively. RESULTS: Lead was negatively associated to hemoglobin (p
publishDate 2006
dc.date.none.fl_str_mv 2006-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/31984
10.1590/S0034-89102006000100012
url https://www.revistas.usp.br/rsp/article/view/31984
identifier_str_mv 10.1590/S0034-89102006000100012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/31984/33995
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 40 No. 1 (2006); 71-76
Revista de Saúde Pública; Vol. 40 Núm. 1 (2006); 71-76
Revista de Saúde Pública; v. 40 n. 1 (2006); 71-76
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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