Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012

Detalhes bibliográficos
Autor(a) principal: Monteiro, Lorena Dias
Data de Publicação: 2015
Outros Autores: Martins-Melo, Francisco Rogerlândio, Brito, Aline Lima, Alencar, Carlos Henrique, Heukelbach, Jorg
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/130451
Resumo: ABSTRACT OBJECTIVE To describe the spatial patterns of leprosy in the Brazilian state of Tocantins. METHODS This study was based on morbidity data obtained from the Sistema de Informações de Agravos de Notificação (SINAN – Brazilian Notifiable Diseases Information System), of the Ministry of Health. All new leprosy cases in individuals residing in the state of Tocantins, between 2001 and 2012, were included. In addition to the description of general disease indicators, a descriptive spatial analysis, empirical Bayesian analysis and spatial dependence analysis were performed by means of global and local Moran’s indexes. RESULTS A total of 14,542 new cases were recorded during the period under study. Based on the annual case detection rate, 77.0% of the municipalities were classified as hyperendemic (>; 40 cases/100,000 inhabitants). Regarding the annual case detection rate in < 15 years-olds, 65.4% of the municipalities were hyperendemic (10.0 to 19.9 cases/100,000 inhabitants); 26.6% had a detection rate of grade 2 disability cases between 5.0 and 9.9 cases/100,000 inhabitants. There was a geographical overlap of clusters of municipalities with high detection rates in hyperendemic areas. Clusters with high disease risk (global Moran’s index: 0.51; p < 0.001), ongoing transmission (0.47; p < 0.001) and late diagnosis (0.44; p < 0.001) were identified mainly in the central-north and southwestern regions of Tocantins. CONCLUSIONS We identified high-risk clusters for transmission and late diagnosis of leprosy in the Brazilian state of Tocantins. Surveillance and control measures should be prioritized in these high-risk municipalities.
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spelling Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012Spatial patterns of leprosy in a hyperendemic state in Northern Brazil, 2001-2012HanseníaseepidemiologiaAnálise EspacialDoenças EndêmicasDoenças NegligenciadasVigilância EpidemiológicaLeprosyepidemiologySpatial AnalysisEndemic DiseasesNeglected DiseasesEpidemiological SurveillanceABSTRACT OBJECTIVE To describe the spatial patterns of leprosy in the Brazilian state of Tocantins. METHODS This study was based on morbidity data obtained from the Sistema de Informações de Agravos de Notificação (SINAN – Brazilian Notifiable Diseases Information System), of the Ministry of Health. All new leprosy cases in individuals residing in the state of Tocantins, between 2001 and 2012, were included. In addition to the description of general disease indicators, a descriptive spatial analysis, empirical Bayesian analysis and spatial dependence analysis were performed by means of global and local Moran’s indexes. RESULTS A total of 14,542 new cases were recorded during the period under study. Based on the annual case detection rate, 77.0% of the municipalities were classified as hyperendemic (>; 40 cases/100,000 inhabitants). Regarding the annual case detection rate in < 15 years-olds, 65.4% of the municipalities were hyperendemic (10.0 to 19.9 cases/100,000 inhabitants); 26.6% had a detection rate of grade 2 disability cases between 5.0 and 9.9 cases/100,000 inhabitants. There was a geographical overlap of clusters of municipalities with high detection rates in hyperendemic areas. Clusters with high disease risk (global Moran’s index: 0.51; p < 0.001), ongoing transmission (0.47; p < 0.001) and late diagnosis (0.44; p < 0.001) were identified mainly in the central-north and southwestern regions of Tocantins. CONCLUSIONS We identified high-risk clusters for transmission and late diagnosis of leprosy in the Brazilian state of Tocantins. Surveillance and control measures should be prioritized in these high-risk municipalities.RESUMO OBJETIVO : Descrever os padrões espaciais da hanseníase no estado do Tocantins. MÉTODOS : Estudo baseado em dados de morbidade obtidos do Sistema de Informações de Agravos de Notificação (Sinan), do Ministério da Saúde. Foram incluídos todos os casos novos de hanseníase residentes no estado do Tocantins, entre 2001 a 2012. Além da descrição dos indicadores gerais da doença, foi realizada análise espacial descritiva, análise bayesiana empírica local e análise de dependência espacial por meio dos índices de Moran global e local. RESULTADOS : Foram registrados 14.532 casos novos no período estudado. Pelo coeficiente de detecção geral, 77,0% dos municípios foram classificados como hiperendêmicos (&gt;; 40 casos/100.000 habitantes). Para a detecção em menores de 15 anos, 65,4% foram hiperendêmicos (10,0 a 19,9 casos/100 mil habitantes), e 26,6% apresentaram detecção com grau 2 de incapacidade entre 5,0 e 9,9 casos/100 mil habitantes. Houve sobreposição geográfica de aglomerados de municípios com elevados coeficientes de detecção em áreas hiperendêmicas. Foram identificados aglomerados de alto risco para ocorrência (índice global de Moran: 0,51; p &lt; 0,001), transmissão ativa (0,47; p &lt; 0,001) e diagnóstico tardio da doença (0,44; p &lt; 0,001), localizados principalmente nas regiões centro-norte e sudoeste do estado. CONCLUSÕES : Existem aglomerados de elevado risco para transmissão e diagnóstico tardio da hanseníase no estado do Tocantins. As medidas de vigilância e controle devem ser priorizadas nos municípios de alto risco identificados.Universidade de São Paulo. Faculdade de Saúde Pública2015-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/13045110.1590/S0034-8910.2015049005866Revista de Saúde Pública; Vol. 49 (2015); 84Revista de Saúde Pública; Vol. 49 (2015); 84Revista de Saúde Pública; v. 49 (2015); 841518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPengporhttps://www.revistas.usp.br/rsp/article/view/130451/126859https://www.revistas.usp.br/rsp/article/view/130451/126860Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessMonteiro, Lorena DiasMartins-Melo, Francisco RogerlândioBrito, Aline LimaAlencar, Carlos HenriqueHeukelbach, Jorg2017-09-27T11:03:36Zoai:revistas.usp.br:article/130451Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2017-09-27T11:03:36Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
Spatial patterns of leprosy in a hyperendemic state in Northern Brazil, 2001-2012
title Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
spellingShingle Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
Monteiro, Lorena Dias
Hanseníase
epidemiologia
Análise Espacial
Doenças Endêmicas
Doenças Negligenciadas
Vigilância Epidemiológica
Leprosy
epidemiology
Spatial Analysis
Endemic Diseases
Neglected Diseases
Epidemiological Surveillance
title_short Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
title_full Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
title_fullStr Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
title_full_unstemmed Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
title_sort Padrões espaciais da hanseníase em um estado hiperendêmico no Norte do Brasil, 2001-2012
author Monteiro, Lorena Dias
author_facet Monteiro, Lorena Dias
Martins-Melo, Francisco Rogerlândio
Brito, Aline Lima
Alencar, Carlos Henrique
Heukelbach, Jorg
author_role author
author2 Martins-Melo, Francisco Rogerlândio
Brito, Aline Lima
Alencar, Carlos Henrique
Heukelbach, Jorg
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Monteiro, Lorena Dias
Martins-Melo, Francisco Rogerlândio
Brito, Aline Lima
Alencar, Carlos Henrique
Heukelbach, Jorg
dc.subject.por.fl_str_mv Hanseníase
epidemiologia
Análise Espacial
Doenças Endêmicas
Doenças Negligenciadas
Vigilância Epidemiológica
Leprosy
epidemiology
Spatial Analysis
Endemic Diseases
Neglected Diseases
Epidemiological Surveillance
topic Hanseníase
epidemiologia
Análise Espacial
Doenças Endêmicas
Doenças Negligenciadas
Vigilância Epidemiológica
Leprosy
epidemiology
Spatial Analysis
Endemic Diseases
Neglected Diseases
Epidemiological Surveillance
description ABSTRACT OBJECTIVE To describe the spatial patterns of leprosy in the Brazilian state of Tocantins. METHODS This study was based on morbidity data obtained from the Sistema de Informações de Agravos de Notificação (SINAN – Brazilian Notifiable Diseases Information System), of the Ministry of Health. All new leprosy cases in individuals residing in the state of Tocantins, between 2001 and 2012, were included. In addition to the description of general disease indicators, a descriptive spatial analysis, empirical Bayesian analysis and spatial dependence analysis were performed by means of global and local Moran’s indexes. RESULTS A total of 14,542 new cases were recorded during the period under study. Based on the annual case detection rate, 77.0% of the municipalities were classified as hyperendemic (>; 40 cases/100,000 inhabitants). Regarding the annual case detection rate in < 15 years-olds, 65.4% of the municipalities were hyperendemic (10.0 to 19.9 cases/100,000 inhabitants); 26.6% had a detection rate of grade 2 disability cases between 5.0 and 9.9 cases/100,000 inhabitants. There was a geographical overlap of clusters of municipalities with high detection rates in hyperendemic areas. Clusters with high disease risk (global Moran’s index: 0.51; p < 0.001), ongoing transmission (0.47; p < 0.001) and late diagnosis (0.44; p < 0.001) were identified mainly in the central-north and southwestern regions of Tocantins. CONCLUSIONS We identified high-risk clusters for transmission and late diagnosis of leprosy in the Brazilian state of Tocantins. Surveillance and control measures should be prioritized in these high-risk municipalities.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/130451
10.1590/S0034-8910.2015049005866
url https://www.revistas.usp.br/rsp/article/view/130451
identifier_str_mv 10.1590/S0034-8910.2015049005866
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/130451/126859
https://www.revistas.usp.br/rsp/article/view/130451/126860
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 49 (2015); 84
Revista de Saúde Pública; Vol. 49 (2015); 84
Revista de Saúde Pública; v. 49 (2015); 84
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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