Quality of life in individuals initiating antiretroviral therapy: a cohort study
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102020000100316 |
Resumo: | ABSTRACT OBJECTIVE To assess longitudinally the change in quality of life in people living with HIV initiating antiretroviral therapy in three public reference services specialized in HIV care in Belo Horizonte, Brazil. METHODS Prospective cohort study among people living with HIV, aged 18 years or older, and initiating antiretroviral therapy. We obtained sociodemographic, behavioral, clinical data related to pharmacological treatment and to the service by face-to-face interviews, and supplemented these data with information from clinical records and Information Systems of the Brazilian HIV/AIDS Program. We measured the quality of life using the WHOQOL-HIV bref instrument, with a minimum interval of six months between the baseline and the follow-up interviews. We used paired t-test to assess the mean change in quality of life between the two interviewsand evaluated factors associated with this outcome using multiple linear regression. RESULTS The overall quality of life, as well as the physical, psychological, level of independence, environment and spiritual quality of life domains were statistically higher in people living with HIV using antiretroviral therapy at the end of the follow-up. Factors independently associated with the increase in quality of life were having religious belief and living with other people. Having signs or symptoms of anxiety and depression and the number of adverse drug reactions reported were predictors associated with worsening quality of life. CONCLUSIONS These results show an improvement in the quality of life over time in people living with HIV on antiretroviral therapy. They also highlight the need to monitor and provide health care support, especially for individuals with signs and symptoms of anxiety and depression and that report adverse reactions to medicines at the beginning of treatment. |
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Revista de Saúde Pública |
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Quality of life in individuals initiating antiretroviral therapy: a cohort studyAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveQuality of LifeWHOQOLHIV-brefCohort StudiesABSTRACT OBJECTIVE To assess longitudinally the change in quality of life in people living with HIV initiating antiretroviral therapy in three public reference services specialized in HIV care in Belo Horizonte, Brazil. METHODS Prospective cohort study among people living with HIV, aged 18 years or older, and initiating antiretroviral therapy. We obtained sociodemographic, behavioral, clinical data related to pharmacological treatment and to the service by face-to-face interviews, and supplemented these data with information from clinical records and Information Systems of the Brazilian HIV/AIDS Program. We measured the quality of life using the WHOQOL-HIV bref instrument, with a minimum interval of six months between the baseline and the follow-up interviews. We used paired t-test to assess the mean change in quality of life between the two interviewsand evaluated factors associated with this outcome using multiple linear regression. RESULTS The overall quality of life, as well as the physical, psychological, level of independence, environment and spiritual quality of life domains were statistically higher in people living with HIV using antiretroviral therapy at the end of the follow-up. Factors independently associated with the increase in quality of life were having religious belief and living with other people. Having signs or symptoms of anxiety and depression and the number of adverse drug reactions reported were predictors associated with worsening quality of life. CONCLUSIONS These results show an improvement in the quality of life over time in people living with HIV on antiretroviral therapy. They also highlight the need to monitor and provide health care support, especially for individuals with signs and symptoms of anxiety and depression and that report adverse reactions to medicines at the beginning of treatment.Faculdade de Saúde Pública da Universidade de São Paulo2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102020000100316Revista de Saúde Pública v.54 2020reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.11606/s1518-8787.2020054001920info:eu-repo/semantics/openAccessPimentel,Gabriela SalesCeccato,Maria das Graças BragaCosta,Juliana de OliveiraMendes,Jullye CamposBonolo,Palmira de FátimaSilveira,Micheline Rosaeng2020-12-14T00:00:00Zoai:scielo:S0034-89102020000100316Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2020-12-14T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
title |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
spellingShingle |
Quality of life in individuals initiating antiretroviral therapy: a cohort study Pimentel,Gabriela Sales Anti-HIV Agents Antiretroviral Therapy, Highly Active Quality of Life WHOQOLHIV-bref Cohort Studies |
title_short |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
title_full |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
title_fullStr |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
title_full_unstemmed |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
title_sort |
Quality of life in individuals initiating antiretroviral therapy: a cohort study |
author |
Pimentel,Gabriela Sales |
author_facet |
Pimentel,Gabriela Sales Ceccato,Maria das Graças Braga Costa,Juliana de Oliveira Mendes,Jullye Campos Bonolo,Palmira de Fátima Silveira,Micheline Rosa |
author_role |
author |
author2 |
Ceccato,Maria das Graças Braga Costa,Juliana de Oliveira Mendes,Jullye Campos Bonolo,Palmira de Fátima Silveira,Micheline Rosa |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Pimentel,Gabriela Sales Ceccato,Maria das Graças Braga Costa,Juliana de Oliveira Mendes,Jullye Campos Bonolo,Palmira de Fátima Silveira,Micheline Rosa |
dc.subject.por.fl_str_mv |
Anti-HIV Agents Antiretroviral Therapy, Highly Active Quality of Life WHOQOLHIV-bref Cohort Studies |
topic |
Anti-HIV Agents Antiretroviral Therapy, Highly Active Quality of Life WHOQOLHIV-bref Cohort Studies |
description |
ABSTRACT OBJECTIVE To assess longitudinally the change in quality of life in people living with HIV initiating antiretroviral therapy in three public reference services specialized in HIV care in Belo Horizonte, Brazil. METHODS Prospective cohort study among people living with HIV, aged 18 years or older, and initiating antiretroviral therapy. We obtained sociodemographic, behavioral, clinical data related to pharmacological treatment and to the service by face-to-face interviews, and supplemented these data with information from clinical records and Information Systems of the Brazilian HIV/AIDS Program. We measured the quality of life using the WHOQOL-HIV bref instrument, with a minimum interval of six months between the baseline and the follow-up interviews. We used paired t-test to assess the mean change in quality of life between the two interviewsand evaluated factors associated with this outcome using multiple linear regression. RESULTS The overall quality of life, as well as the physical, psychological, level of independence, environment and spiritual quality of life domains were statistically higher in people living with HIV using antiretroviral therapy at the end of the follow-up. Factors independently associated with the increase in quality of life were having religious belief and living with other people. Having signs or symptoms of anxiety and depression and the number of adverse drug reactions reported were predictors associated with worsening quality of life. CONCLUSIONS These results show an improvement in the quality of life over time in people living with HIV on antiretroviral therapy. They also highlight the need to monitor and provide health care support, especially for individuals with signs and symptoms of anxiety and depression and that report adverse reactions to medicines at the beginning of treatment. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102020000100316 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102020000100316 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.11606/s1518-8787.2020054001920 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
publisher.none.fl_str_mv |
Faculdade de Saúde Pública da Universidade de São Paulo |
dc.source.none.fl_str_mv |
Revista de Saúde Pública v.54 2020 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1748936506120077312 |