Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | https://www.revistas.usp.br/rsp/article/view/32200 |
Resumo: | OBJECTIVE: The occurrence of drug adverse events in hospital settings is high and generates cost excess. The purpose of the study was to identify drug-related events during hospital admissions and to estimate their prevalence. METHODS: A retrospective study was carried out in the State of Rio de Janeiro, Southeastern Brazil. Hospitalizations from the Brazilian Health System's national hospital database during the period between 1999 and 2002 were assessed. Admitted cases including suspected drug adverse event cases with ICD-10 (2000) coding in the main diagnosis and/or secondary diagnosis fields were included in the study. Means and standard deviations of continuous variables as well as the statistical significance of differences were estimated using variance analysis (ANOVA with a 95% confidence interval). RESULTS: There were identified 3,421 drug-related adverse events, and a prevalence of 1.8 cases per 1,000 hospitalizations was estimated. Most cases occurred in males (64.5%) admitted in contracted (34.9%) and local public hospitals (23.1%) in the departments of psychiatry (51.4%) and internal medicine (45.2%), of them, 84.1% were discharged. Most of them were adverse drug reactions or drug poisoning, and there were significant difference (p |
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Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil Agravos provocados por medicamentos em hospitais do Estado do Rio de Janeiro, Brasil Preparações farmacêuticas^i1^sefeitos adverToxicidade de drogasFarmacoepidemiologiaSistemas de Informação HospitalarSistema Único de SaúdePharmaceutical preparations^i2^sadverse effeDrug toxicityPharmacoepidemiologyHospital Information SystemsNational Health System (BR) OBJECTIVE: The occurrence of drug adverse events in hospital settings is high and generates cost excess. The purpose of the study was to identify drug-related events during hospital admissions and to estimate their prevalence. METHODS: A retrospective study was carried out in the State of Rio de Janeiro, Southeastern Brazil. Hospitalizations from the Brazilian Health System's national hospital database during the period between 1999 and 2002 were assessed. Admitted cases including suspected drug adverse event cases with ICD-10 (2000) coding in the main diagnosis and/or secondary diagnosis fields were included in the study. Means and standard deviations of continuous variables as well as the statistical significance of differences were estimated using variance analysis (ANOVA with a 95% confidence interval). RESULTS: There were identified 3,421 drug-related adverse events, and a prevalence of 1.8 cases per 1,000 hospitalizations was estimated. Most cases occurred in males (64.5%) admitted in contracted (34.9%) and local public hospitals (23.1%) in the departments of psychiatry (51.4%) and internal medicine (45.2%), of them, 84.1% were discharged. Most of them were adverse drug reactions or drug poisoning, and there were significant difference (p OBJETIVO: A ocorrência de agravos provocados por medicamentos no meio hospitalar é elevada e gera custos excedentes. O objetivo do estudo foi identificar problemas relacionados a medicamentos ocorridos durante a internação hospitalar e estimar a prevalência desses agravos. MÉTODOS: Estudo retrospectivo realizado no Estado do Rio de Janeiro. Foram analisadas as internações pagas pelo Sistema Único de Saúde entre 1999 e 2002. Os dados foram extraídos do Sistema de Informações Hospitalares. Selecionaram-se as internações que apresentaram um dos códigos da CID-10 (2000) suspeitos de serem agravos provocados por medicamentos, que estivessem nos campos do diagnóstico principal e/ou do diagnóstico secundário. Para as variáveis contínuas estimou-se a média, e o desvio-padrão, sendo a significância estatística entre as diferenças testada por meio de análise de variância (ANOVA, com intervalo de confiança de 95%). RESULTADOS: Foram identificados 3.421 casos equivalentes à freqüência de 1,8 casos/1.000 internações, ocorridos, sobretudo, em homens (64,5%), nos hospitais contratados (34,9%) e nos municipais (23,1%), nos leitos de psiquiatria (51,4%) e de clínica médica (45,2%), dos quais 84,1% resultaram em alta. A maioria dos agravos foi por reações adversas e de intoxicações e, entre essas categorias, há diferenças significativas (pUniversidade de São Paulo. Faculdade de Saúde Pública2007-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/3220010.1590/S0034-89102006005000012Revista de Saúde Pública; Vol. 41 No. 1 (2007); 108-115 Revista de Saúde Pública; Vol. 41 Núm. 1 (2007); 108-115 Revista de Saúde Pública; v. 41 n. 1 (2007); 108-115 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/32200/34305Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessRozenfeld, Suely2012-07-09T00:29:12Zoai:revistas.usp.br:article/32200Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-07-09T00:29:12Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil Agravos provocados por medicamentos em hospitais do Estado do Rio de Janeiro, Brasil |
title |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil |
spellingShingle |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil Rozenfeld, Suely Preparações farmacêuticas^i1^sefeitos adver Toxicidade de drogas Farmacoepidemiologia Sistemas de Informação Hospitalar Sistema Único de Saúde Pharmaceutical preparations^i2^sadverse effe Drug toxicity Pharmacoepidemiology Hospital Information Systems National Health System (BR) |
title_short |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil |
title_full |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil |
title_fullStr |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil |
title_full_unstemmed |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil |
title_sort |
Drug adverse events in hospitals in the State of Rio de Janeiro, Brazil |
author |
Rozenfeld, Suely |
author_facet |
Rozenfeld, Suely |
author_role |
author |
dc.contributor.author.fl_str_mv |
Rozenfeld, Suely |
dc.subject.por.fl_str_mv |
Preparações farmacêuticas^i1^sefeitos adver Toxicidade de drogas Farmacoepidemiologia Sistemas de Informação Hospitalar Sistema Único de Saúde Pharmaceutical preparations^i2^sadverse effe Drug toxicity Pharmacoepidemiology Hospital Information Systems National Health System (BR) |
topic |
Preparações farmacêuticas^i1^sefeitos adver Toxicidade de drogas Farmacoepidemiologia Sistemas de Informação Hospitalar Sistema Único de Saúde Pharmaceutical preparations^i2^sadverse effe Drug toxicity Pharmacoepidemiology Hospital Information Systems National Health System (BR) |
description |
OBJECTIVE: The occurrence of drug adverse events in hospital settings is high and generates cost excess. The purpose of the study was to identify drug-related events during hospital admissions and to estimate their prevalence. METHODS: A retrospective study was carried out in the State of Rio de Janeiro, Southeastern Brazil. Hospitalizations from the Brazilian Health System's national hospital database during the period between 1999 and 2002 were assessed. Admitted cases including suspected drug adverse event cases with ICD-10 (2000) coding in the main diagnosis and/or secondary diagnosis fields were included in the study. Means and standard deviations of continuous variables as well as the statistical significance of differences were estimated using variance analysis (ANOVA with a 95% confidence interval). RESULTS: There were identified 3,421 drug-related adverse events, and a prevalence of 1.8 cases per 1,000 hospitalizations was estimated. Most cases occurred in males (64.5%) admitted in contracted (34.9%) and local public hospitals (23.1%) in the departments of psychiatry (51.4%) and internal medicine (45.2%), of them, 84.1% were discharged. Most of them were adverse drug reactions or drug poisoning, and there were significant difference (p |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/32200 10.1590/S0034-89102006005000012 |
url |
https://www.revistas.usp.br/rsp/article/view/32200 |
identifier_str_mv |
10.1590/S0034-89102006005000012 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/32200/34305 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Revista de Saúde Pública info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Revista de Saúde Pública |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
dc.source.none.fl_str_mv |
Revista de Saúde Pública; Vol. 41 No. 1 (2007); 108-115 Revista de Saúde Pública; Vol. 41 Núm. 1 (2007); 108-115 Revista de Saúde Pública; v. 41 n. 1 (2007); 108-115 1518-8787 0034-8910 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1800221786015531008 |