Multifactorial intervention for diabetes control among older users of insulin

Detalhes bibliográficos
Autor(a) principal: Machry,Rafael Vaz
Data de Publicação: 2018
Outros Autores: Pedroso,Henrique Umpierre, Vasconcellos,Luthiele Silva, Nunes,Rafaela Ramos, Evaldt,Cibelle de Abreu, Yunes Filho,Eduardo Bardou, Rodrigues,Ticiana da Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100247
Resumo: ABSTRACT OBJECTIVE: To evaluate if the closer follow-up with the supply of insulin pens and the measurement of capillary blood glucose improve the management of older patients with type 2 diabetes without adequate glycemic control despite extensive therapy. METHODS: This is a prospective, non-randomized, quasi-experimental study. We have included 45 patients over 60 years old, from both sexes, with glycated hemoglobin (HbA1c) > 8.5% using oral hypoglycemic agents and insulin. The intervention consisted of monthly medical visits, with the provision of insulin pens and strips for blood glucose measurement. All patients received insulin pen, refills of Neutral Protamine Hagedorn and regular insulin, needles for the pen, blood glucose meter, and capillary blood glucose tests (three tests/day). Treatment was adjusted with the same endocrinologist monthly for six months. Glycated hemoglobin was measured at baseline and 12 and 24 weeks after intervention. RESULTS: Glycated hemoglobin at baseline was 10.34% (SE = 0.22%) and 8.54% (SE = 0.24%, p < 0.001) and 8.09% (SE = 0.21%, p < 0.001) at 12 and 24 weeks after intervention, respectively, with a significant reduction from baseline. CONCLUSIONS: More frequent medical visits, with treatment inputs including the use of insulin pens and self-monitoring, have improved glycemic control (reduction of 2.25% in HbA1C, on average, at 24 weeks of follow-up). Our data support a change in the management and medical behavior of older patients with chronically decompensated diabetes.
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spelling Multifactorial intervention for diabetes control among older users of insulinAgedDiabetes Mellitus, prevention &amp; controlGlycemic Index, drug effectsHypoglycemic AgentsInsulin, administration &amp; dosageBlood Glucose Self-MonitoringClinical TrialABSTRACT OBJECTIVE: To evaluate if the closer follow-up with the supply of insulin pens and the measurement of capillary blood glucose improve the management of older patients with type 2 diabetes without adequate glycemic control despite extensive therapy. METHODS: This is a prospective, non-randomized, quasi-experimental study. We have included 45 patients over 60 years old, from both sexes, with glycated hemoglobin (HbA1c) > 8.5% using oral hypoglycemic agents and insulin. The intervention consisted of monthly medical visits, with the provision of insulin pens and strips for blood glucose measurement. All patients received insulin pen, refills of Neutral Protamine Hagedorn and regular insulin, needles for the pen, blood glucose meter, and capillary blood glucose tests (three tests/day). Treatment was adjusted with the same endocrinologist monthly for six months. Glycated hemoglobin was measured at baseline and 12 and 24 weeks after intervention. RESULTS: Glycated hemoglobin at baseline was 10.34% (SE = 0.22%) and 8.54% (SE = 0.24%, p < 0.001) and 8.09% (SE = 0.21%, p < 0.001) at 12 and 24 weeks after intervention, respectively, with a significant reduction from baseline. CONCLUSIONS: More frequent medical visits, with treatment inputs including the use of insulin pens and self-monitoring, have improved glycemic control (reduction of 2.25% in HbA1C, on average, at 24 weeks of follow-up). Our data support a change in the management and medical behavior of older patients with chronically decompensated diabetes.Faculdade de Saúde Pública da Universidade de São Paulo2018-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100247Revista de Saúde Pública v.52 2018reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.11606/s1518-8787.2018052000144info:eu-repo/semantics/openAccessMachry,Rafael VazPedroso,Henrique UmpierreVasconcellos,Luthiele SilvaNunes,Rafaela RamosEvaldt,Cibelle de AbreuYunes Filho,Eduardo BardouRodrigues,Ticiana da Costaeng2018-05-15T00:00:00Zoai:scielo:S0034-89102018000100247Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2018-05-15T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Multifactorial intervention for diabetes control among older users of insulin
title Multifactorial intervention for diabetes control among older users of insulin
spellingShingle Multifactorial intervention for diabetes control among older users of insulin
Machry,Rafael Vaz
Aged
Diabetes Mellitus, prevention &amp; control
Glycemic Index, drug effects
Hypoglycemic Agents
Insulin, administration &amp; dosage
Blood Glucose Self-Monitoring
Clinical Trial
title_short Multifactorial intervention for diabetes control among older users of insulin
title_full Multifactorial intervention for diabetes control among older users of insulin
title_fullStr Multifactorial intervention for diabetes control among older users of insulin
title_full_unstemmed Multifactorial intervention for diabetes control among older users of insulin
title_sort Multifactorial intervention for diabetes control among older users of insulin
author Machry,Rafael Vaz
author_facet Machry,Rafael Vaz
Pedroso,Henrique Umpierre
Vasconcellos,Luthiele Silva
Nunes,Rafaela Ramos
Evaldt,Cibelle de Abreu
Yunes Filho,Eduardo Bardou
Rodrigues,Ticiana da Costa
author_role author
author2 Pedroso,Henrique Umpierre
Vasconcellos,Luthiele Silva
Nunes,Rafaela Ramos
Evaldt,Cibelle de Abreu
Yunes Filho,Eduardo Bardou
Rodrigues,Ticiana da Costa
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Machry,Rafael Vaz
Pedroso,Henrique Umpierre
Vasconcellos,Luthiele Silva
Nunes,Rafaela Ramos
Evaldt,Cibelle de Abreu
Yunes Filho,Eduardo Bardou
Rodrigues,Ticiana da Costa
dc.subject.por.fl_str_mv Aged
Diabetes Mellitus, prevention &amp; control
Glycemic Index, drug effects
Hypoglycemic Agents
Insulin, administration &amp; dosage
Blood Glucose Self-Monitoring
Clinical Trial
topic Aged
Diabetes Mellitus, prevention &amp; control
Glycemic Index, drug effects
Hypoglycemic Agents
Insulin, administration &amp; dosage
Blood Glucose Self-Monitoring
Clinical Trial
description ABSTRACT OBJECTIVE: To evaluate if the closer follow-up with the supply of insulin pens and the measurement of capillary blood glucose improve the management of older patients with type 2 diabetes without adequate glycemic control despite extensive therapy. METHODS: This is a prospective, non-randomized, quasi-experimental study. We have included 45 patients over 60 years old, from both sexes, with glycated hemoglobin (HbA1c) > 8.5% using oral hypoglycemic agents and insulin. The intervention consisted of monthly medical visits, with the provision of insulin pens and strips for blood glucose measurement. All patients received insulin pen, refills of Neutral Protamine Hagedorn and regular insulin, needles for the pen, blood glucose meter, and capillary blood glucose tests (three tests/day). Treatment was adjusted with the same endocrinologist monthly for six months. Glycated hemoglobin was measured at baseline and 12 and 24 weeks after intervention. RESULTS: Glycated hemoglobin at baseline was 10.34% (SE = 0.22%) and 8.54% (SE = 0.24%, p < 0.001) and 8.09% (SE = 0.21%, p < 0.001) at 12 and 24 weeks after intervention, respectively, with a significant reduction from baseline. CONCLUSIONS: More frequent medical visits, with treatment inputs including the use of insulin pens and self-monitoring, have improved glycemic control (reduction of 2.25% in HbA1C, on average, at 24 weeks of follow-up). Our data support a change in the management and medical behavior of older patients with chronically decompensated diabetes.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100247
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102018000100247
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.11606/s1518-8787.2018052000144
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
dc.source.none.fl_str_mv Revista de Saúde Pública v.52 2018
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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