Risk factors for HIV infection among patients infected with hepatitis C virus
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Data de Publicação: | 2006 |
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Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | https://www.revistas.usp.br/rsp/article/view/32064 |
Resumo: | OBJECTIVE: Human immunodeficiency virus and hepatitis C virus share the same routes of transmission. Currently, there is a high frequency of co-infection worldwide, especially among users of injectable drugs and in subjects with history of blood transfusions. The aim of the present study was to evaluate risk factors associated to human immunodeficiency virus infection in patients infected with hepatitis C virus. METHODS: We carried out an epidemiological case-control study, including 118 patients (cases) infected by both viruses and 233 patients (controls) infected only by the hepatitis C virus. Between January 1999 and November 2001, patients responded to a questionnaire assessing sociodemographic and professional characteristics, and major risk factors for virus infection. After description and initial comparison, variables were evaluated by univariate analysis and then by multivariate logistic regression for variables selected through the maximum likelihood test. RESULTS: Co-infection was associated with female sex (OR=2.89; 95% CI: 1.16-7.08), being divorced/widow (OR=3.91; 95% CI: 1.34-11.35), past or current use of illegal drugs (OR=3.96; 95% CI: 1.55-10.13) and to the habit of sharing pipes or needles (OR=10.28; 95% CI: 4.00-6.42). CONCLUSIONS: Among patients infected with hepatitis C virus, female sex is a risk factor for HIV infection after adjustment for the habit of sharing pipes and needles. Being divorced/widow, use of illegal drugs, and the habit of sharing pipes and syringes were associated to co-infection. |
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Risk factors for HIV infection among patients infected with hepatitis C virus Fatores de risco para infecção pelo HIV em pacientes com o vírus da hepatite C Risk factorsAcquired immunodeficiency syndrome^i2^sepidemiolAcquired immunodeficiency syndrome^i2^stransmissHepatitis C^i2^sepidemiolHepatitis C^i2^stransmissCase-control studiesQuestionnairesSocioeconomic factorsSexual behaviorFatores de riscoSíndrome de imunodeficiência adquirida^i1^sepidemioloSíndrome de imunodeficiência adquirida^i1^stransmisHepatite C^i1^sepidemioloHepatite C^i1^stransmisEstudos de casos e controlesQuestionáriosFatores socioeconômicosComportamento sexual OBJECTIVE: Human immunodeficiency virus and hepatitis C virus share the same routes of transmission. Currently, there is a high frequency of co-infection worldwide, especially among users of injectable drugs and in subjects with history of blood transfusions. The aim of the present study was to evaluate risk factors associated to human immunodeficiency virus infection in patients infected with hepatitis C virus. METHODS: We carried out an epidemiological case-control study, including 118 patients (cases) infected by both viruses and 233 patients (controls) infected only by the hepatitis C virus. Between January 1999 and November 2001, patients responded to a questionnaire assessing sociodemographic and professional characteristics, and major risk factors for virus infection. After description and initial comparison, variables were evaluated by univariate analysis and then by multivariate logistic regression for variables selected through the maximum likelihood test. RESULTS: Co-infection was associated with female sex (OR=2.89; 95% CI: 1.16-7.08), being divorced/widow (OR=3.91; 95% CI: 1.34-11.35), past or current use of illegal drugs (OR=3.96; 95% CI: 1.55-10.13) and to the habit of sharing pipes or needles (OR=10.28; 95% CI: 4.00-6.42). CONCLUSIONS: Among patients infected with hepatitis C virus, female sex is a risk factor for HIV infection after adjustment for the habit of sharing pipes and needles. Being divorced/widow, use of illegal drugs, and the habit of sharing pipes and syringes were associated to co-infection. OBJETIVO: Os vírus da imunodeficiência humana e o vírus da hepatite C apresentam fatores de transmissão em comum. Atualmente, há alta freqüência da co-infecção, principalmente em indivíduos usuários de drogas injetáveis e com história de transfusões. O objetivo do estudo foi avaliar os fatores de risco para infecção pelo HIV em pacientes infectados pelo vírus da hepatite C. MÉTODOS: Trata-se de estudo epidemiológico do tipo caso-controle, realizado com 118 pacientes (casos) infectados pelos vírus HIV e vírus da hepatite C e 233 pacientes (controles) infectados somente pelo vírus da hepatite C. Entre janeiro de 1999 a novembro de 2001, os pacientes foram submetidos a questionário sobre características sociodemográficas, profissionais, e principais fatores de risco para infecção pelos vírus. Após descritas e comparadas, as variáveis foram submetidas à análise univariada, e em seguida à análise de regressão logística para variáveis selecionadas pelo teste da razão da máxima verossimilhança. RESULTADOS: A co-infecção está associada ao sexo feminino (OR=2,89; IC 95%: 1,16-7,08), aos estados civis separado/viúvo (OR=3,91; IC 95%: 1,34-11,35), ao uso pregresso ou atual de drogas ilícitas (OR=3,96; IC 95%: 1,55-0,13) e ao hábito de compartilhar canudos ou seringas (OR=10,28; IC 95%: 4,00-6,42). CONCLUSÕES: Em pacientes infectados pelo vírus da hepatite C, o sexo feminino é fator de risco para a infecção pelo HIV quando ajustado à variável compartilhar canudos ou seringas. Os estados civis separado/viúvo, uso de drogas ilícitas e hábito de compartilhar canudos ou seringas são, também, fatores associados ao risco para esta co-infecção. Universidade de São Paulo. Faculdade de Saúde Pública2006-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/3206410.1590/S0034-89102006000300017Revista de Saúde Pública; Vol. 40 No. 3 (2006); 482-488 Revista de Saúde Pública; Vol. 40 Núm. 3 (2006); 482-488 Revista de Saúde Pública; v. 40 n. 3 (2006); 482-488 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporenghttps://www.revistas.usp.br/rsp/article/view/32064/34114https://www.revistas.usp.br/rsp/article/view/32064/34115Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessSilva, Anita Campos MendonçaBarone, Antônio Alci2012-07-08T23:06:25Zoai:revistas.usp.br:article/32064Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-07-08T23:06:25Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Risk factors for HIV infection among patients infected with hepatitis C virus Fatores de risco para infecção pelo HIV em pacientes com o vírus da hepatite C |
title |
Risk factors for HIV infection among patients infected with hepatitis C virus |
spellingShingle |
Risk factors for HIV infection among patients infected with hepatitis C virus Silva, Anita Campos Mendonça Risk factors Acquired immunodeficiency syndrome^i2^sepidemiol Acquired immunodeficiency syndrome^i2^stransmiss Hepatitis C^i2^sepidemiol Hepatitis C^i2^stransmiss Case-control studies Questionnaires Socioeconomic factors Sexual behavior Fatores de risco Síndrome de imunodeficiência adquirida^i1^sepidemiolo Síndrome de imunodeficiência adquirida^i1^stransmis Hepatite C^i1^sepidemiolo Hepatite C^i1^stransmis Estudos de casos e controles Questionários Fatores socioeconômicos Comportamento sexual |
title_short |
Risk factors for HIV infection among patients infected with hepatitis C virus |
title_full |
Risk factors for HIV infection among patients infected with hepatitis C virus |
title_fullStr |
Risk factors for HIV infection among patients infected with hepatitis C virus |
title_full_unstemmed |
Risk factors for HIV infection among patients infected with hepatitis C virus |
title_sort |
Risk factors for HIV infection among patients infected with hepatitis C virus |
author |
Silva, Anita Campos Mendonça |
author_facet |
Silva, Anita Campos Mendonça Barone, Antônio Alci |
author_role |
author |
author2 |
Barone, Antônio Alci |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Silva, Anita Campos Mendonça Barone, Antônio Alci |
dc.subject.por.fl_str_mv |
Risk factors Acquired immunodeficiency syndrome^i2^sepidemiol Acquired immunodeficiency syndrome^i2^stransmiss Hepatitis C^i2^sepidemiol Hepatitis C^i2^stransmiss Case-control studies Questionnaires Socioeconomic factors Sexual behavior Fatores de risco Síndrome de imunodeficiência adquirida^i1^sepidemiolo Síndrome de imunodeficiência adquirida^i1^stransmis Hepatite C^i1^sepidemiolo Hepatite C^i1^stransmis Estudos de casos e controles Questionários Fatores socioeconômicos Comportamento sexual |
topic |
Risk factors Acquired immunodeficiency syndrome^i2^sepidemiol Acquired immunodeficiency syndrome^i2^stransmiss Hepatitis C^i2^sepidemiol Hepatitis C^i2^stransmiss Case-control studies Questionnaires Socioeconomic factors Sexual behavior Fatores de risco Síndrome de imunodeficiência adquirida^i1^sepidemiolo Síndrome de imunodeficiência adquirida^i1^stransmis Hepatite C^i1^sepidemiolo Hepatite C^i1^stransmis Estudos de casos e controles Questionários Fatores socioeconômicos Comportamento sexual |
description |
OBJECTIVE: Human immunodeficiency virus and hepatitis C virus share the same routes of transmission. Currently, there is a high frequency of co-infection worldwide, especially among users of injectable drugs and in subjects with history of blood transfusions. The aim of the present study was to evaluate risk factors associated to human immunodeficiency virus infection in patients infected with hepatitis C virus. METHODS: We carried out an epidemiological case-control study, including 118 patients (cases) infected by both viruses and 233 patients (controls) infected only by the hepatitis C virus. Between January 1999 and November 2001, patients responded to a questionnaire assessing sociodemographic and professional characteristics, and major risk factors for virus infection. After description and initial comparison, variables were evaluated by univariate analysis and then by multivariate logistic regression for variables selected through the maximum likelihood test. RESULTS: Co-infection was associated with female sex (OR=2.89; 95% CI: 1.16-7.08), being divorced/widow (OR=3.91; 95% CI: 1.34-11.35), past or current use of illegal drugs (OR=3.96; 95% CI: 1.55-10.13) and to the habit of sharing pipes or needles (OR=10.28; 95% CI: 4.00-6.42). CONCLUSIONS: Among patients infected with hepatitis C virus, female sex is a risk factor for HIV infection after adjustment for the habit of sharing pipes and needles. Being divorced/widow, use of illegal drugs, and the habit of sharing pipes and syringes were associated to co-infection. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/32064 10.1590/S0034-89102006000300017 |
url |
https://www.revistas.usp.br/rsp/article/view/32064 |
identifier_str_mv |
10.1590/S0034-89102006000300017 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/32064/34114 https://www.revistas.usp.br/rsp/article/view/32064/34115 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Revista de Saúde Pública info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Revista de Saúde Pública |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
dc.source.none.fl_str_mv |
Revista de Saúde Pública; Vol. 40 No. 3 (2006); 482-488 Revista de Saúde Pública; Vol. 40 Núm. 3 (2006); 482-488 Revista de Saúde Pública; v. 40 n. 3 (2006); 482-488 1518-8787 0034-8910 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1800221784642945024 |