Risk factors for HIV infection among patients infected with hepatitis C virus

Detalhes bibliográficos
Autor(a) principal: Silva, Anita Campos Mendonça
Data de Publicação: 2006
Outros Autores: Barone, Antônio Alci
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/32064
Resumo: OBJECTIVE: Human immunodeficiency virus and hepatitis C virus share the same routes of transmission. Currently, there is a high frequency of co-infection worldwide, especially among users of injectable drugs and in subjects with history of blood transfusions. The aim of the present study was to evaluate risk factors associated to human immunodeficiency virus infection in patients infected with hepatitis C virus. METHODS: We carried out an epidemiological case-control study, including 118 patients (cases) infected by both viruses and 233 patients (controls) infected only by the hepatitis C virus. Between January 1999 and November 2001, patients responded to a questionnaire assessing sociodemographic and professional characteristics, and major risk factors for virus infection. After description and initial comparison, variables were evaluated by univariate analysis and then by multivariate logistic regression for variables selected through the maximum likelihood test. RESULTS: Co-infection was associated with female sex (OR=2.89; 95% CI: 1.16-7.08), being divorced/widow (OR=3.91; 95% CI: 1.34-11.35), past or current use of illegal drugs (OR=3.96; 95% CI: 1.55-10.13) and to the habit of sharing pipes or needles (OR=10.28; 95% CI: 4.00-6.42). CONCLUSIONS: Among patients infected with hepatitis C virus, female sex is a risk factor for HIV infection after adjustment for the habit of sharing pipes and needles. Being divorced/widow, use of illegal drugs, and the habit of sharing pipes and syringes were associated to co-infection.
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spelling Risk factors for HIV infection among patients infected with hepatitis C virus Fatores de risco para infecção pelo HIV em pacientes com o vírus da hepatite C Risk factorsAcquired immunodeficiency syndrome^i2^sepidemiolAcquired immunodeficiency syndrome^i2^stransmissHepatitis C^i2^sepidemiolHepatitis C^i2^stransmissCase-control studiesQuestionnairesSocioeconomic factorsSexual behaviorFatores de riscoSíndrome de imunodeficiência adquirida^i1^sepidemioloSíndrome de imunodeficiência adquirida^i1^stransmisHepatite C^i1^sepidemioloHepatite C^i1^stransmisEstudos de casos e controlesQuestionáriosFatores socioeconômicosComportamento sexual OBJECTIVE: Human immunodeficiency virus and hepatitis C virus share the same routes of transmission. Currently, there is a high frequency of co-infection worldwide, especially among users of injectable drugs and in subjects with history of blood transfusions. The aim of the present study was to evaluate risk factors associated to human immunodeficiency virus infection in patients infected with hepatitis C virus. METHODS: We carried out an epidemiological case-control study, including 118 patients (cases) infected by both viruses and 233 patients (controls) infected only by the hepatitis C virus. Between January 1999 and November 2001, patients responded to a questionnaire assessing sociodemographic and professional characteristics, and major risk factors for virus infection. After description and initial comparison, variables were evaluated by univariate analysis and then by multivariate logistic regression for variables selected through the maximum likelihood test. RESULTS: Co-infection was associated with female sex (OR=2.89; 95% CI: 1.16-7.08), being divorced/widow (OR=3.91; 95% CI: 1.34-11.35), past or current use of illegal drugs (OR=3.96; 95% CI: 1.55-10.13) and to the habit of sharing pipes or needles (OR=10.28; 95% CI: 4.00-6.42). CONCLUSIONS: Among patients infected with hepatitis C virus, female sex is a risk factor for HIV infection after adjustment for the habit of sharing pipes and needles. Being divorced/widow, use of illegal drugs, and the habit of sharing pipes and syringes were associated to co-infection. OBJETIVO: Os vírus da imunodeficiência humana e o vírus da hepatite C apresentam fatores de transmissão em comum. Atualmente, há alta freqüência da co-infecção, principalmente em indivíduos usuários de drogas injetáveis e com história de transfusões. O objetivo do estudo foi avaliar os fatores de risco para infecção pelo HIV em pacientes infectados pelo vírus da hepatite C. MÉTODOS: Trata-se de estudo epidemiológico do tipo caso-controle, realizado com 118 pacientes (casos) infectados pelos vírus HIV e vírus da hepatite C e 233 pacientes (controles) infectados somente pelo vírus da hepatite C. Entre janeiro de 1999 a novembro de 2001, os pacientes foram submetidos a questionário sobre características sociodemográficas, profissionais, e principais fatores de risco para infecção pelos vírus. Após descritas e comparadas, as variáveis foram submetidas à análise univariada, e em seguida à análise de regressão logística para variáveis selecionadas pelo teste da razão da máxima verossimilhança. RESULTADOS: A co-infecção está associada ao sexo feminino (OR=2,89; IC 95%: 1,16-7,08), aos estados civis separado/viúvo (OR=3,91; IC 95%: 1,34-11,35), ao uso pregresso ou atual de drogas ilícitas (OR=3,96; IC 95%: 1,55-0,13) e ao hábito de compartilhar canudos ou seringas (OR=10,28; IC 95%: 4,00-6,42). CONCLUSÕES: Em pacientes infectados pelo vírus da hepatite C, o sexo feminino é fator de risco para a infecção pelo HIV quando ajustado à variável compartilhar canudos ou seringas. Os estados civis separado/viúvo, uso de drogas ilícitas e hábito de compartilhar canudos ou seringas são, também, fatores associados ao risco para esta co-infecção. Universidade de São Paulo. Faculdade de Saúde Pública2006-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/3206410.1590/S0034-89102006000300017Revista de Saúde Pública; Vol. 40 No. 3 (2006); 482-488 Revista de Saúde Pública; Vol. 40 Núm. 3 (2006); 482-488 Revista de Saúde Pública; v. 40 n. 3 (2006); 482-488 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporenghttps://www.revistas.usp.br/rsp/article/view/32064/34114https://www.revistas.usp.br/rsp/article/view/32064/34115Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessSilva, Anita Campos MendonçaBarone, Antônio Alci2012-07-08T23:06:25Zoai:revistas.usp.br:article/32064Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-07-08T23:06:25Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Risk factors for HIV infection among patients infected with hepatitis C virus
Fatores de risco para infecção pelo HIV em pacientes com o vírus da hepatite C
title Risk factors for HIV infection among patients infected with hepatitis C virus
spellingShingle Risk factors for HIV infection among patients infected with hepatitis C virus
Silva, Anita Campos Mendonça
Risk factors
Acquired immunodeficiency syndrome^i2^sepidemiol
Acquired immunodeficiency syndrome^i2^stransmiss
Hepatitis C^i2^sepidemiol
Hepatitis C^i2^stransmiss
Case-control studies
Questionnaires
Socioeconomic factors
Sexual behavior
Fatores de risco
Síndrome de imunodeficiência adquirida^i1^sepidemiolo
Síndrome de imunodeficiência adquirida^i1^stransmis
Hepatite C^i1^sepidemiolo
Hepatite C^i1^stransmis
Estudos de casos e controles
Questionários
Fatores socioeconômicos
Comportamento sexual
title_short Risk factors for HIV infection among patients infected with hepatitis C virus
title_full Risk factors for HIV infection among patients infected with hepatitis C virus
title_fullStr Risk factors for HIV infection among patients infected with hepatitis C virus
title_full_unstemmed Risk factors for HIV infection among patients infected with hepatitis C virus
title_sort Risk factors for HIV infection among patients infected with hepatitis C virus
author Silva, Anita Campos Mendonça
author_facet Silva, Anita Campos Mendonça
Barone, Antônio Alci
author_role author
author2 Barone, Antônio Alci
author2_role author
dc.contributor.author.fl_str_mv Silva, Anita Campos Mendonça
Barone, Antônio Alci
dc.subject.por.fl_str_mv Risk factors
Acquired immunodeficiency syndrome^i2^sepidemiol
Acquired immunodeficiency syndrome^i2^stransmiss
Hepatitis C^i2^sepidemiol
Hepatitis C^i2^stransmiss
Case-control studies
Questionnaires
Socioeconomic factors
Sexual behavior
Fatores de risco
Síndrome de imunodeficiência adquirida^i1^sepidemiolo
Síndrome de imunodeficiência adquirida^i1^stransmis
Hepatite C^i1^sepidemiolo
Hepatite C^i1^stransmis
Estudos de casos e controles
Questionários
Fatores socioeconômicos
Comportamento sexual
topic Risk factors
Acquired immunodeficiency syndrome^i2^sepidemiol
Acquired immunodeficiency syndrome^i2^stransmiss
Hepatitis C^i2^sepidemiol
Hepatitis C^i2^stransmiss
Case-control studies
Questionnaires
Socioeconomic factors
Sexual behavior
Fatores de risco
Síndrome de imunodeficiência adquirida^i1^sepidemiolo
Síndrome de imunodeficiência adquirida^i1^stransmis
Hepatite C^i1^sepidemiolo
Hepatite C^i1^stransmis
Estudos de casos e controles
Questionários
Fatores socioeconômicos
Comportamento sexual
description OBJECTIVE: Human immunodeficiency virus and hepatitis C virus share the same routes of transmission. Currently, there is a high frequency of co-infection worldwide, especially among users of injectable drugs and in subjects with history of blood transfusions. The aim of the present study was to evaluate risk factors associated to human immunodeficiency virus infection in patients infected with hepatitis C virus. METHODS: We carried out an epidemiological case-control study, including 118 patients (cases) infected by both viruses and 233 patients (controls) infected only by the hepatitis C virus. Between January 1999 and November 2001, patients responded to a questionnaire assessing sociodemographic and professional characteristics, and major risk factors for virus infection. After description and initial comparison, variables were evaluated by univariate analysis and then by multivariate logistic regression for variables selected through the maximum likelihood test. RESULTS: Co-infection was associated with female sex (OR=2.89; 95% CI: 1.16-7.08), being divorced/widow (OR=3.91; 95% CI: 1.34-11.35), past or current use of illegal drugs (OR=3.96; 95% CI: 1.55-10.13) and to the habit of sharing pipes or needles (OR=10.28; 95% CI: 4.00-6.42). CONCLUSIONS: Among patients infected with hepatitis C virus, female sex is a risk factor for HIV infection after adjustment for the habit of sharing pipes and needles. Being divorced/widow, use of illegal drugs, and the habit of sharing pipes and syringes were associated to co-infection.
publishDate 2006
dc.date.none.fl_str_mv 2006-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/32064
10.1590/S0034-89102006000300017
url https://www.revistas.usp.br/rsp/article/view/32064
identifier_str_mv 10.1590/S0034-89102006000300017
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/32064/34114
https://www.revistas.usp.br/rsp/article/view/32064/34115
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 40 No. 3 (2006); 482-488
Revista de Saúde Pública; Vol. 40 Núm. 3 (2006); 482-488
Revista de Saúde Pública; v. 40 n. 3 (2006); 482-488
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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