Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights

Detalhes bibliográficos
Autor(a) principal: Zanotti-Magalhães, Eliana Maria
Data de Publicação: 1995
Outros Autores: Magalhães, Luiz Augusto, Carvalho, José Ferreira de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/24122
Resumo: The relationship between the development of hepatomegaly, splenomegaly, body weight and mortality rate and the degree of susceptibility of Biomphalaria glabrata and B. tenagophila at which infective cercariae developed was studied. The study utilized Swiss mice, SPF, as definitive hosts and populations of snails genetically selected for character susceptibility as intermediate hosts. Low body weight and smaller viscera were observed in infected mice with cercariae originating from snails that showed a high degree of susceptibility. The higher susceptibility of molluscs infected with S. mansoni corresponded to a lower survival of the infected mice. These results lead to the conclusion that the higher degree of adaptation of the parasite to its intermediate hosts, evidenced by the high indexes of susceptibility, leads to different behaviour on the part of this parasite in its definitive host.
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spelling Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights Relação entre a patogenicidade do Schistosoma mansoni em camundongos e a susceptibilidade do molusco vetor: III. Mortalidade, pesos corporal e das vísceras Biomphalaria^i1^sparasitoloSchistosoma mansoni^i1^spatogenicidHepatomegalia^i1^sepidemioloEsplenomegalia^i1^sepidemioloBiomphalaria^i2^sparasitolSchistosoma mansoni^i2^spathogenicHepatomegaly^i2^sepidemiolSplenomegaly^i2^sepidemiol The relationship between the development of hepatomegaly, splenomegaly, body weight and mortality rate and the degree of susceptibility of Biomphalaria glabrata and B. tenagophila at which infective cercariae developed was studied. The study utilized Swiss mice, SPF, as definitive hosts and populations of snails genetically selected for character susceptibility as intermediate hosts. Low body weight and smaller viscera were observed in infected mice with cercariae originating from snails that showed a high degree of susceptibility. The higher susceptibility of molluscs infected with S. mansoni corresponded to a lower survival of the infected mice. These results lead to the conclusion that the higher degree of adaptation of the parasite to its intermediate hosts, evidenced by the high indexes of susceptibility, leads to different behaviour on the part of this parasite in its definitive host. Estudou-se a relação entre o desenvolvimento da hepatomegalia, da esplenomegalia, peso corporal e taxa de mortalidade em camundongos experimentalmente infectados por Schistosoma mansoni com o grau de susceptibilidade de Biomphalaria glahrata e B. tenagophila nas quais se desenvolveram as cercárias infectantes respectivamente, das linhagens BH e SJ. Foram utilizados como hospedeiro definitivo camundongos Swiss, SPF e como hospedeiros intermediários populações de moluscos selecionados geneticamente para o caráter susceptibilidade. Foram observados menores pesos corporais e das visceras em camundongos infectados com cercárias provenientes de moluscos que apresentaram elevado grau de susceptibilidade. A maior susceptibilidade dos moluscos à infecção pelo S. mansoni correspondeu a uma menor sobrevivência dos camundongos infectados. Os resultados fazem crer que a maior adaptação do parasita ao hospedeiro intermediário, traduzidos pelas taxas mais elevadas de susceptibilidade, pode levar a um comportamento diferente deste parasita no hospedeiro definitivo. Universidade de São Paulo. Faculdade de Saúde Pública1995-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2412210.1590/S0034-89101995000400002Revista de Saúde Pública; Vol. 29 No. 4 (1995); 265-270 Revista de Saúde Pública; Vol. 29 Núm. 4 (1995); 265-270 Revista de Saúde Pública; v. 29 n. 4 (1995); 265-270 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/24122/26087Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessZanotti-Magalhães, Eliana MariaMagalhães, Luiz AugustoCarvalho, José Ferreira de2012-05-29T16:29:09Zoai:revistas.usp.br:article/24122Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-29T16:29:09Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
Relação entre a patogenicidade do Schistosoma mansoni em camundongos e a susceptibilidade do molusco vetor: III. Mortalidade, pesos corporal e das vísceras
title Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
spellingShingle Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
Zanotti-Magalhães, Eliana Maria
Biomphalaria^i1^sparasitolo
Schistosoma mansoni^i1^spatogenicid
Hepatomegalia^i1^sepidemiolo
Esplenomegalia^i1^sepidemiolo
Biomphalaria^i2^sparasitol
Schistosoma mansoni^i2^spathogenic
Hepatomegaly^i2^sepidemiol
Splenomegaly^i2^sepidemiol
title_short Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
title_full Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
title_fullStr Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
title_full_unstemmed Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
title_sort Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
author Zanotti-Magalhães, Eliana Maria
author_facet Zanotti-Magalhães, Eliana Maria
Magalhães, Luiz Augusto
Carvalho, José Ferreira de
author_role author
author2 Magalhães, Luiz Augusto
Carvalho, José Ferreira de
author2_role author
author
dc.contributor.author.fl_str_mv Zanotti-Magalhães, Eliana Maria
Magalhães, Luiz Augusto
Carvalho, José Ferreira de
dc.subject.por.fl_str_mv Biomphalaria^i1^sparasitolo
Schistosoma mansoni^i1^spatogenicid
Hepatomegalia^i1^sepidemiolo
Esplenomegalia^i1^sepidemiolo
Biomphalaria^i2^sparasitol
Schistosoma mansoni^i2^spathogenic
Hepatomegaly^i2^sepidemiol
Splenomegaly^i2^sepidemiol
topic Biomphalaria^i1^sparasitolo
Schistosoma mansoni^i1^spatogenicid
Hepatomegalia^i1^sepidemiolo
Esplenomegalia^i1^sepidemiolo
Biomphalaria^i2^sparasitol
Schistosoma mansoni^i2^spathogenic
Hepatomegaly^i2^sepidemiol
Splenomegaly^i2^sepidemiol
description The relationship between the development of hepatomegaly, splenomegaly, body weight and mortality rate and the degree of susceptibility of Biomphalaria glabrata and B. tenagophila at which infective cercariae developed was studied. The study utilized Swiss mice, SPF, as definitive hosts and populations of snails genetically selected for character susceptibility as intermediate hosts. Low body weight and smaller viscera were observed in infected mice with cercariae originating from snails that showed a high degree of susceptibility. The higher susceptibility of molluscs infected with S. mansoni corresponded to a lower survival of the infected mice. These results lead to the conclusion that the higher degree of adaptation of the parasite to its intermediate hosts, evidenced by the high indexes of susceptibility, leads to different behaviour on the part of this parasite in its definitive host.
publishDate 1995
dc.date.none.fl_str_mv 1995-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/24122
10.1590/S0034-89101995000400002
url https://www.revistas.usp.br/rsp/article/view/24122
identifier_str_mv 10.1590/S0034-89101995000400002
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/24122/26087
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 29 No. 4 (1995); 265-270
Revista de Saúde Pública; Vol. 29 Núm. 4 (1995); 265-270
Revista de Saúde Pública; v. 29 n. 4 (1995); 265-270
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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