Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights
Autor(a) principal: | |
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Data de Publicação: | 1995 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista de Saúde Pública |
Texto Completo: | https://www.revistas.usp.br/rsp/article/view/24122 |
Resumo: | The relationship between the development of hepatomegaly, splenomegaly, body weight and mortality rate and the degree of susceptibility of Biomphalaria glabrata and B. tenagophila at which infective cercariae developed was studied. The study utilized Swiss mice, SPF, as definitive hosts and populations of snails genetically selected for character susceptibility as intermediate hosts. Low body weight and smaller viscera were observed in infected mice with cercariae originating from snails that showed a high degree of susceptibility. The higher susceptibility of molluscs infected with S. mansoni corresponded to a lower survival of the infected mice. These results lead to the conclusion that the higher degree of adaptation of the parasite to its intermediate hosts, evidenced by the high indexes of susceptibility, leads to different behaviour on the part of this parasite in its definitive host. |
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Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights Relação entre a patogenicidade do Schistosoma mansoni em camundongos e a susceptibilidade do molusco vetor: III. Mortalidade, pesos corporal e das vísceras Biomphalaria^i1^sparasitoloSchistosoma mansoni^i1^spatogenicidHepatomegalia^i1^sepidemioloEsplenomegalia^i1^sepidemioloBiomphalaria^i2^sparasitolSchistosoma mansoni^i2^spathogenicHepatomegaly^i2^sepidemiolSplenomegaly^i2^sepidemiol The relationship between the development of hepatomegaly, splenomegaly, body weight and mortality rate and the degree of susceptibility of Biomphalaria glabrata and B. tenagophila at which infective cercariae developed was studied. The study utilized Swiss mice, SPF, as definitive hosts and populations of snails genetically selected for character susceptibility as intermediate hosts. Low body weight and smaller viscera were observed in infected mice with cercariae originating from snails that showed a high degree of susceptibility. The higher susceptibility of molluscs infected with S. mansoni corresponded to a lower survival of the infected mice. These results lead to the conclusion that the higher degree of adaptation of the parasite to its intermediate hosts, evidenced by the high indexes of susceptibility, leads to different behaviour on the part of this parasite in its definitive host. Estudou-se a relação entre o desenvolvimento da hepatomegalia, da esplenomegalia, peso corporal e taxa de mortalidade em camundongos experimentalmente infectados por Schistosoma mansoni com o grau de susceptibilidade de Biomphalaria glahrata e B. tenagophila nas quais se desenvolveram as cercárias infectantes respectivamente, das linhagens BH e SJ. Foram utilizados como hospedeiro definitivo camundongos Swiss, SPF e como hospedeiros intermediários populações de moluscos selecionados geneticamente para o caráter susceptibilidade. Foram observados menores pesos corporais e das visceras em camundongos infectados com cercárias provenientes de moluscos que apresentaram elevado grau de susceptibilidade. A maior susceptibilidade dos moluscos à infecção pelo S. mansoni correspondeu a uma menor sobrevivência dos camundongos infectados. Os resultados fazem crer que a maior adaptação do parasita ao hospedeiro intermediário, traduzidos pelas taxas mais elevadas de susceptibilidade, pode levar a um comportamento diferente deste parasita no hospedeiro definitivo. Universidade de São Paulo. Faculdade de Saúde Pública1995-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2412210.1590/S0034-89101995000400002Revista de Saúde Pública; Vol. 29 No. 4 (1995); 265-270 Revista de Saúde Pública; Vol. 29 Núm. 4 (1995); 265-270 Revista de Saúde Pública; v. 29 n. 4 (1995); 265-270 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/24122/26087Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessZanotti-Magalhães, Eliana MariaMagalhães, Luiz AugustoCarvalho, José Ferreira de2012-05-29T16:29:09Zoai:revistas.usp.br:article/24122Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-29T16:29:09Revista de Saúde Pública - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights Relação entre a patogenicidade do Schistosoma mansoni em camundongos e a susceptibilidade do molusco vetor: III. Mortalidade, pesos corporal e das vísceras |
title |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights |
spellingShingle |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights Zanotti-Magalhães, Eliana Maria Biomphalaria^i1^sparasitolo Schistosoma mansoni^i1^spatogenicid Hepatomegalia^i1^sepidemiolo Esplenomegalia^i1^sepidemiolo Biomphalaria^i2^sparasitol Schistosoma mansoni^i2^spathogenic Hepatomegaly^i2^sepidemiol Splenomegaly^i2^sepidemiol |
title_short |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights |
title_full |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights |
title_fullStr |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights |
title_full_unstemmed |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights |
title_sort |
Relationship between the pathogenicity of Schistosoma mansoni in mice and the susceptibility of the vector mollusc: III. Mortality, body weight and viscera weights |
author |
Zanotti-Magalhães, Eliana Maria |
author_facet |
Zanotti-Magalhães, Eliana Maria Magalhães, Luiz Augusto Carvalho, José Ferreira de |
author_role |
author |
author2 |
Magalhães, Luiz Augusto Carvalho, José Ferreira de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Zanotti-Magalhães, Eliana Maria Magalhães, Luiz Augusto Carvalho, José Ferreira de |
dc.subject.por.fl_str_mv |
Biomphalaria^i1^sparasitolo Schistosoma mansoni^i1^spatogenicid Hepatomegalia^i1^sepidemiolo Esplenomegalia^i1^sepidemiolo Biomphalaria^i2^sparasitol Schistosoma mansoni^i2^spathogenic Hepatomegaly^i2^sepidemiol Splenomegaly^i2^sepidemiol |
topic |
Biomphalaria^i1^sparasitolo Schistosoma mansoni^i1^spatogenicid Hepatomegalia^i1^sepidemiolo Esplenomegalia^i1^sepidemiolo Biomphalaria^i2^sparasitol Schistosoma mansoni^i2^spathogenic Hepatomegaly^i2^sepidemiol Splenomegaly^i2^sepidemiol |
description |
The relationship between the development of hepatomegaly, splenomegaly, body weight and mortality rate and the degree of susceptibility of Biomphalaria glabrata and B. tenagophila at which infective cercariae developed was studied. The study utilized Swiss mice, SPF, as definitive hosts and populations of snails genetically selected for character susceptibility as intermediate hosts. Low body weight and smaller viscera were observed in infected mice with cercariae originating from snails that showed a high degree of susceptibility. The higher susceptibility of molluscs infected with S. mansoni corresponded to a lower survival of the infected mice. These results lead to the conclusion that the higher degree of adaptation of the parasite to its intermediate hosts, evidenced by the high indexes of susceptibility, leads to different behaviour on the part of this parasite in its definitive host. |
publishDate |
1995 |
dc.date.none.fl_str_mv |
1995-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/24122 10.1590/S0034-89101995000400002 |
url |
https://www.revistas.usp.br/rsp/article/view/24122 |
identifier_str_mv |
10.1590/S0034-89101995000400002 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/rsp/article/view/24122/26087 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Revista de Saúde Pública info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Revista de Saúde Pública |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Saúde Pública |
dc.source.none.fl_str_mv |
Revista de Saúde Pública; Vol. 29 No. 4 (1995); 265-270 Revista de Saúde Pública; Vol. 29 Núm. 4 (1995); 265-270 Revista de Saúde Pública; v. 29 n. 4 (1995); 265-270 1518-8787 0034-8910 reponame:Revista de Saúde Pública instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Revista de Saúde Pública |
collection |
Revista de Saúde Pública |
repository.name.fl_str_mv |
Revista de Saúde Pública - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
revsp@org.usp.br||revsp1@usp.br |
_version_ |
1800221777632165888 |