Seroprevalence of SARS-CoV-2 antibodies in schoolchildren in the city of São Paulo, 2020

• Autor(a) principal: Kamioka, Gabriela Akemi
• Data de Publicação: 2023
• Outros Autores: Madalosso, Geraldine, Albuquerque, José Olimpio Moura de, Costa, Selma Anequini, Ferreira, Paula Bisordi, Sato, Ana Paula Sayuri, Glasser, Paula Regina, Pino, Francisco Alberto, Burihan, Patrícia Carla Piragibe Ramos, Carvalho, Ana Carolina Aguiar de, Amorim, Ana Beatriz Pagliaro, Cavazzana, Cinthya Luzia, Aires, Caroline Cotrim, Kataoka, Ana Paula Arruda Geraldes, Savani, Elisa San Martin Mouriz, Bessa, Thirsa Alvares Franco, Aguiar, Breno Souza de, Failla, Marcelo Antunes, Santos, Edson Aparecido dos, Brito, Edjane Maria Torreão, Santos, Maria Cristina Honório dos, Caldeira, Luiz Artur Vieira, Saboia e Silva, Solange Maria, Zamarco, Luiz Carlos, Fonseca, Sandra Maria Sabino, Lima, Marcia Maria de Cerqueira, Marques, Ivanilda Argenau, Mauro, Athenê Maria de Marco França, Masi, Eduardo de
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Revista de Saúde Pública
• Texto Completo: https://www.revistas.usp.br/rsp/article/view/212138
• topic: Criança; Adolescente; COVID-19, epidemiologia; SARS-CoV-2; Estudos Soroepidemiológicos; Child; Adolescent; COVID-19, epidemiology; SARS-CoV-2; Seroepidemiologic Studies

OBJECTIVE: To estimate seroprevalence of SARS-CoV-2 antibodies in schoolchildren aged 4 to 14 years living in the city of São Paulo, according to clinical, demographic, epidemiological, and social variables, during the school closure period as a measure against covid-19 spread. METHODS: A serological survey was made in September 2020 with a random sample stratified by school system (municipal public, state public and private) type. A venous blood sample was collected using the Wondfo SARS-CoV-2 Antibody Test (lateral flow method) for detection of total SARS-CoV-2 virus antibodies. Semi-structured questionnaires were applied to collect clinical, demographic, social, and epidemiological data. RESULTS: Seroprevalence of SARS-CoV-2 antibodies in schoolchildren was of 16.6% (95%CI 15.4–17.8). The study found higher seroprevalence in the municipal (18.5%; 95%CI 16.6–20.6) and state (16.2%; 95%CI 14.4–18.2) public school systems compared to the private school system (11.7; 95%CI 10.0–13.7), among black and brown students (18.4%; 95%CI 16.8–20.2) and in the most vulnerable social stratum (18.5 %;95%CI 16.9–20.2). Lower seroprevalence was identified in schoolchildren who reported following the recommended protective measures against covid-19. CONCLUSION: Seroprevalence of SARS-CoV-2 antibodies is found mainly in the most socially vulnerable schoolchildren. This study can contribute to support public policies that reinforce the importance of suspending face-to-face classes and developing strategies aimed at protective measures and monitoring of the serological status of those who have not yet been included in the vaccination schedule.