Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus

Detalhes bibliográficos
Autor(a) principal: Stewien, Klaus Eberhard
Data de Publicação: 1971
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/4599
Resumo: A comparative study of the susceptibility of different strains of human diploid cells (FH1, FH3, FH4, FH11, FH13, FH14, FH15) to cytomegalovirus disclosed a relation between the capacity of growing and producing a consistent cytophatic effect of human cytomegalovirus strains and the homogeneous characteristics of the tissue cultures. The cell strains FH3 and FH16 were insusceptible when fibroblasts and epithelial cells were present in the same culture. After a certain number of passages, when the fibroblastic characteristics of cells in the cultures was established, the cytophatic effect could be consistently observed.
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spelling Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus Estudo comparativo da susceptibilidade de linhagens de células diplóides humanas ao vírus da citomegalia (VCM) Vírus citomegálicoCélulas diplóides humanasCorpúsculos de inclusãoCytomegalovirusHuman diploid strainsBodiesinclusion A comparative study of the susceptibility of different strains of human diploid cells (FH1, FH3, FH4, FH11, FH13, FH14, FH15) to cytomegalovirus disclosed a relation between the capacity of growing and producing a consistent cytophatic effect of human cytomegalovirus strains and the homogeneous characteristics of the tissue cultures. The cell strains FH3 and FH16 were insusceptible when fibroblasts and epithelial cells were present in the same culture. After a certain number of passages, when the fibroblastic characteristics of cells in the cultures was established, the cytophatic effect could be consistently observed. São apresentados os resultados de um estudo comparativo da susceptibilidade de diversas linhagens de células diplóides humanas (FH1, FH3, FH4, FH11 , FH13, FH14, FH16) ao vírus da citomegalia (VCM). Das linhagens referidas, tôdas se mostraram sensíveis aos vírus estudados, com exceção das linhagens FH3 e FH16; estas vieram mostrar o mesmo grau de susceptibilidade depois de várias sub-culturas, no momento em que o aspecto morfológico da camada celular passou de heterogêneo - células fibroblásticas e epiteliais - a homogêneo - células fibroblásticas. Universidade de São Paulo. Faculdade de Saúde Pública1971-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/459910.1590/S0034-89101971000100007Revista de Saúde Pública; Vol. 5 No. 1 (1971); 59-65 Revista de Saúde Pública; Vol. 5 Núm. 1 (1971); 59-65 Revista de Saúde Pública; v. 5 n. 1 (1971); 59-65 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/4599/6128Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessStewien, Klaus Eberhard2012-04-27T19:01:06Zoai:revistas.usp.br:article/4599Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-04-27T19:01:06Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
Estudo comparativo da susceptibilidade de linhagens de células diplóides humanas ao vírus da citomegalia (VCM)
title Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
spellingShingle Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
Stewien, Klaus Eberhard
Vírus citomegálico
Células diplóides humanas
Corpúsculos de inclusão
Cytomegalovirus
Human diploid strains
Bodies
inclusion
title_short Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
title_full Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
title_fullStr Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
title_full_unstemmed Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
title_sort Comparative study of the susceptibility of human diploid cell strains to the cytomegalovirus
author Stewien, Klaus Eberhard
author_facet Stewien, Klaus Eberhard
author_role author
dc.contributor.author.fl_str_mv Stewien, Klaus Eberhard
dc.subject.por.fl_str_mv Vírus citomegálico
Células diplóides humanas
Corpúsculos de inclusão
Cytomegalovirus
Human diploid strains
Bodies
inclusion
topic Vírus citomegálico
Células diplóides humanas
Corpúsculos de inclusão
Cytomegalovirus
Human diploid strains
Bodies
inclusion
description A comparative study of the susceptibility of different strains of human diploid cells (FH1, FH3, FH4, FH11, FH13, FH14, FH15) to cytomegalovirus disclosed a relation between the capacity of growing and producing a consistent cytophatic effect of human cytomegalovirus strains and the homogeneous characteristics of the tissue cultures. The cell strains FH3 and FH16 were insusceptible when fibroblasts and epithelial cells were present in the same culture. After a certain number of passages, when the fibroblastic characteristics of cells in the cultures was established, the cytophatic effect could be consistently observed.
publishDate 1971
dc.date.none.fl_str_mv 1971-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4599
10.1590/S0034-89101971000100007
url https://www.revistas.usp.br/rsp/article/view/4599
identifier_str_mv 10.1590/S0034-89101971000100007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4599/6128
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 5 No. 1 (1971); 59-65
Revista de Saúde Pública; Vol. 5 Núm. 1 (1971); 59-65
Revista de Saúde Pública; v. 5 n. 1 (1971); 59-65
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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