Chemotherapy of tuberculosis

Detalhes bibliográficos
Autor(a) principal: Brólio, Roberto
Data de Publicação: 1975
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/4775
Resumo: A review of present knowledge on the treatment of Tuberculosis reveals as to how basic concepts on combination of drugs, prolonged treatment and continuity have evolved. It discloses the tendency towards adoption of new therapeutical schemes and the advantages of intermittent treatment, time reducing and the new concept denomination by which the word "continuity" doesn't necessarily mean "daily" but "with regularity" when medicines are given at regular intervals throughout the intermittent period. The basic principles of chemotherapy, the drugs at present being used as well as their efficacy, toxicity, doses and manner of administration are analysed. The criteria for choice of the best therapeutical scheme, continuity of treatment and main reasons for therapeutical failure are also reviewed.
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spelling Chemotherapy of tuberculosis Quimeoterapia da tuberculose TuberculoseQuimioterapiaMedicamentosEsquemas terapêuticosTuberculosisChemotherapyDrugsTherapeutical schemes A review of present knowledge on the treatment of Tuberculosis reveals as to how basic concepts on combination of drugs, prolonged treatment and continuity have evolved. It discloses the tendency towards adoption of new therapeutical schemes and the advantages of intermittent treatment, time reducing and the new concept denomination by which the word "continuity" doesn't necessarily mean "daily" but "with regularity" when medicines are given at regular intervals throughout the intermittent period. The basic principles of chemotherapy, the drugs at present being used as well as their efficacy, toxicity, doses and manner of administration are analysed. The criteria for choice of the best therapeutical scheme, continuity of treatment and main reasons for therapeutical failure are also reviewed. Uma revisão dos conhecimentos atuais sobre o tratamento da tuberculose revela como evoluiram os conceitos básicos de associação medicamentosa, continuidade e tempo prolongado. Evidencia a tendência para a adoção de novos esquemas terapêuticos e as vantagens do tratamento intermitente, da redução do período de tempo e a nova conotação de conceitos, em que "continuidade" nem sempre significa "diariamente" mas "regularidade", quando os medicamentos são administrados com intervalos, na intermitência. São analisados os princípios básicos da quimioterapia, os medicamentos em uso, sua eficácia, toxicidade, doses e vias de administração. São revistos os critérios para a escolha do melhor esquema terapêutico, continuidade do tratamento e as principais causas de insucesso terapêutico. Universidade de São Paulo. Faculdade de Saúde Pública1975-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/477510.1590/S0034-89101975000100011Revista de Saúde Pública; Vol. 9 No. 1 (1975); 71-85 Revista de Saúde Pública; Vol. 9 Núm. 1 (1975); 71-85 Revista de Saúde Pública; v. 9 n. 1 (1975); 71-85 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/4775/6305Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessBrólio, Roberto2012-04-27T19:10:51Zoai:revistas.usp.br:article/4775Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-04-27T19:10:51Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Chemotherapy of tuberculosis
Quimeoterapia da tuberculose
title Chemotherapy of tuberculosis
spellingShingle Chemotherapy of tuberculosis
Brólio, Roberto
Tuberculose
Quimioterapia
Medicamentos
Esquemas terapêuticos
Tuberculosis
Chemotherapy
Drugs
Therapeutical schemes
title_short Chemotherapy of tuberculosis
title_full Chemotherapy of tuberculosis
title_fullStr Chemotherapy of tuberculosis
title_full_unstemmed Chemotherapy of tuberculosis
title_sort Chemotherapy of tuberculosis
author Brólio, Roberto
author_facet Brólio, Roberto
author_role author
dc.contributor.author.fl_str_mv Brólio, Roberto
dc.subject.por.fl_str_mv Tuberculose
Quimioterapia
Medicamentos
Esquemas terapêuticos
Tuberculosis
Chemotherapy
Drugs
Therapeutical schemes
topic Tuberculose
Quimioterapia
Medicamentos
Esquemas terapêuticos
Tuberculosis
Chemotherapy
Drugs
Therapeutical schemes
description A review of present knowledge on the treatment of Tuberculosis reveals as to how basic concepts on combination of drugs, prolonged treatment and continuity have evolved. It discloses the tendency towards adoption of new therapeutical schemes and the advantages of intermittent treatment, time reducing and the new concept denomination by which the word "continuity" doesn't necessarily mean "daily" but "with regularity" when medicines are given at regular intervals throughout the intermittent period. The basic principles of chemotherapy, the drugs at present being used as well as their efficacy, toxicity, doses and manner of administration are analysed. The criteria for choice of the best therapeutical scheme, continuity of treatment and main reasons for therapeutical failure are also reviewed.
publishDate 1975
dc.date.none.fl_str_mv 1975-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4775
10.1590/S0034-89101975000100011
url https://www.revistas.usp.br/rsp/article/view/4775
identifier_str_mv 10.1590/S0034-89101975000100011
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4775/6305
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 9 No. 1 (1975); 71-85
Revista de Saúde Pública; Vol. 9 Núm. 1 (1975); 71-85
Revista de Saúde Pública; v. 9 n. 1 (1975); 71-85
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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