Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital

Detalhes bibliográficos
Autor(a) principal: Barbosa, Victorio
Data de Publicação: 1975
Outros Autores: Stewien, Klaus E.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/4783
Resumo: The prevalence of neutralizing antibodies for the three types of polioviruses and the immunity levels of different age groups were determined through a seroepidemiological survey, in a population of 0 to 12 year old children, living in the city of S. Paulo and attending the Menino Jesus Hospital. The results showed a high number of children susceptible to infection by polioviruses, mainly in the 9-12 month age bracket where the proportion of individuals completeley susceptible was 42.5%. In this group the prevalence of type 1, 2 and 3 antibodies was only about 40%. For the 0-5 year old children only 60% were found to be double plus triple immune, among those who got three or more doses of oral trivalent vaccine. The results also showed that the immunity status of the children in this group was the same in the three geographical zones of city of S. Paulo, there being abount 50% of double plus triple immune children. These results show low levels of immunity mainly for those in the first year of life. These is then a clear necessity for new serological surveys, besides intensification and improving of routine vaccination against poliomyelitis in our region.
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spelling Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital Estado imunitário relativo à poliomielite das crianças de 0-12 anos, residentes no município de São Paulo, Brasil e assistidas pelo Hospital Menino Jesus PoliomieliteImunidadeInquérito EpidemiológicoSão PauloBrasilPoliovírusPoliomyelitisImmunityEpidemiologic survey^i2^sS. PauloBraPoliovirus The prevalence of neutralizing antibodies for the three types of polioviruses and the immunity levels of different age groups were determined through a seroepidemiological survey, in a population of 0 to 12 year old children, living in the city of S. Paulo and attending the Menino Jesus Hospital. The results showed a high number of children susceptible to infection by polioviruses, mainly in the 9-12 month age bracket where the proportion of individuals completeley susceptible was 42.5%. In this group the prevalence of type 1, 2 and 3 antibodies was only about 40%. For the 0-5 year old children only 60% were found to be double plus triple immune, among those who got three or more doses of oral trivalent vaccine. The results also showed that the immunity status of the children in this group was the same in the three geographical zones of city of S. Paulo, there being abount 50% of double plus triple immune children. These results show low levels of immunity mainly for those in the first year of life. These is then a clear necessity for new serological surveys, besides intensification and improving of routine vaccination against poliomyelitis in our region. A prevalência dos anticorpos neutralizantes contra os três tipos de poliovírus e os níveis de imunidade para diferentes grupos etários foram determinados, através de um inquérito soro-epidemiológico, numa população de crianças de 0-12 anos de idade, residentes no município de São Paulo, Brasil e assistidas pelo Hospital Menino Jesus. Os resultados mostraram um número elevado de crianças suscetíveis à infecção por poliovírus no primeiro ano de vida, particularmente no grupo etário de 9-12 meses, em que a proporção de crianças completamente desprotegidas (triplo-suscetíveis) alcançou 42,5%. Neste grupo, a prevalência de anticorpos dos tipos 1, 2 e 3 foi apenas em torno de 40%. Dentre as crianças do grupo etário de 0-5 anos, que receberam três ou mais doses de vacina oral trivalente, verificou-se a baixa proporção de 60% de duplo mais triplo-imunes. Os resultados mostraram que o estado imunitário das crianças deste grupo foi o mesmo nas três zonas geográficas da Capital, sendo em torno de apenas 50% a proporção de crianças duplo mais triplo-imunes. Estes resultados indicam níveis precários de imunidade, particularmente nas crianças do primeiro ano de vida. Existe, pois, uma necessidade evidente de realizar novos inquéritos sorológicos, além de intensificar e melhorar a vacinação de manutenção contra a poliomielite em nosso meio. Universidade de São Paulo. Faculdade de Saúde Pública1975-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/478310.1590/S0034-89101975000200006Revista de Saúde Pública; Vol. 9 No. 2 (1975); 137-153 Revista de Saúde Pública; Vol. 9 Núm. 2 (1975); 137-153 Revista de Saúde Pública; v. 9 n. 2 (1975); 137-153 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/rsp/article/view/4783/6313Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessBarbosa, VictorioStewien, Klaus E.2012-04-27T19:11:12Zoai:revistas.usp.br:article/4783Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-04-27T19:11:12Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
Estado imunitário relativo à poliomielite das crianças de 0-12 anos, residentes no município de São Paulo, Brasil e assistidas pelo Hospital Menino Jesus
title Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
spellingShingle Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
Barbosa, Victorio
Poliomielite
Imunidade
Inquérito Epidemiológico
São Paulo
Brasil
Poliovírus
Poliomyelitis
Immunity
Epidemiologic survey^i2^sS. Paulo
Bra
Poliovirus
title_short Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
title_full Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
title_fullStr Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
title_full_unstemmed Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
title_sort Immunity status to poliomyelitis of 0-12 years old children living in S. Paulo city, Brazil and using the Menino Jesus Hospital
author Barbosa, Victorio
author_facet Barbosa, Victorio
Stewien, Klaus E.
author_role author
author2 Stewien, Klaus E.
author2_role author
dc.contributor.author.fl_str_mv Barbosa, Victorio
Stewien, Klaus E.
dc.subject.por.fl_str_mv Poliomielite
Imunidade
Inquérito Epidemiológico
São Paulo
Brasil
Poliovírus
Poliomyelitis
Immunity
Epidemiologic survey^i2^sS. Paulo
Bra
Poliovirus
topic Poliomielite
Imunidade
Inquérito Epidemiológico
São Paulo
Brasil
Poliovírus
Poliomyelitis
Immunity
Epidemiologic survey^i2^sS. Paulo
Bra
Poliovirus
description The prevalence of neutralizing antibodies for the three types of polioviruses and the immunity levels of different age groups were determined through a seroepidemiological survey, in a population of 0 to 12 year old children, living in the city of S. Paulo and attending the Menino Jesus Hospital. The results showed a high number of children susceptible to infection by polioviruses, mainly in the 9-12 month age bracket where the proportion of individuals completeley susceptible was 42.5%. In this group the prevalence of type 1, 2 and 3 antibodies was only about 40%. For the 0-5 year old children only 60% were found to be double plus triple immune, among those who got three or more doses of oral trivalent vaccine. The results also showed that the immunity status of the children in this group was the same in the three geographical zones of city of S. Paulo, there being abount 50% of double plus triple immune children. These results show low levels of immunity mainly for those in the first year of life. These is then a clear necessity for new serological surveys, besides intensification and improving of routine vaccination against poliomyelitis in our region.
publishDate 1975
dc.date.none.fl_str_mv 1975-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4783
10.1590/S0034-89101975000200006
url https://www.revistas.usp.br/rsp/article/view/4783
identifier_str_mv 10.1590/S0034-89101975000200006
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/4783/6313
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 9 No. 2 (1975); 137-153
Revista de Saúde Pública; Vol. 9 Núm. 2 (1975); 137-153
Revista de Saúde Pública; v. 9 n. 2 (1975); 137-153
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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