Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina

Detalhes bibliográficos
Autor(a) principal: Stanchi, Nestor Oscar
Data de Publicação: 1993
Outros Autores: Balague, Laura Josefina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/23980
Resumo: Lyme Disease is a tick-borne (specially by Ixodes ticks) immune-mediated inflammatory disorder caused by a newly recognize spirochete, Borrelia burgdorferi. Indirect fluorescent antibody (IF) staining methods and enzyme-linked immunosorbent assay are frequently relied upon to confirm Lyme borreliosis infections. Although serologic testing for antibodies has limitations, it is still the only practical means of confirming B. burgdorferi infections. Because we have no previous report of Lyme disease in human inhabitants in Argentina, a study was designed as a seroepidemiologic investigation of the immune response to B. burgdorferi in farm workers of Argentina with arthritis symptoms. Three out of 28 sera were positive (#1,5 and 9). Serum # 1 was positive for Immunoglobulin G at dilution 1:320, serum # 5 and # 9 both to dilution 1:160; while for Immunoglobulin M all (#1, 5 and 9) were positive at low dilution (1:40) using IF. The results showed that antibodies against B. burgdorferi are present in an Argentinian population. Thus caution should be exercised in the clinical interpretation of arthritis until the presence of B. burgdorferi be confirmed by culture in specific media.
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spelling Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina Doença de Lyme: anticorpos anti Borrelia burgdorferi nos trabalhadores rurais da Argentina Doença de Lyme^i2^sdiagnóstBorrelia Burgdorferi^i2^simunoloTrabalhadores ruraisAnticorpos anti-bactériasLyme disease^i1^sdiagnosBorrelia burgdorferi^i1^simunolRural workersAntibodies^i1^sbacter Lyme Disease is a tick-borne (specially by Ixodes ticks) immune-mediated inflammatory disorder caused by a newly recognize spirochete, Borrelia burgdorferi. Indirect fluorescent antibody (IF) staining methods and enzyme-linked immunosorbent assay are frequently relied upon to confirm Lyme borreliosis infections. Although serologic testing for antibodies has limitations, it is still the only practical means of confirming B. burgdorferi infections. Because we have no previous report of Lyme disease in human inhabitants in Argentina, a study was designed as a seroepidemiologic investigation of the immune response to B. burgdorferi in farm workers of Argentina with arthritis symptoms. Three out of 28 sera were positive (#1,5 and 9). Serum # 1 was positive for Immunoglobulin G at dilution 1:320, serum # 5 and # 9 both to dilution 1:160; while for Immunoglobulin M all (#1, 5 and 9) were positive at low dilution (1:40) using IF. The results showed that antibodies against B. burgdorferi are present in an Argentinian population. Thus caution should be exercised in the clinical interpretation of arthritis until the presence of B. burgdorferi be confirmed by culture in specific media. A doença de Lyme, é uma desordem inflamatória, intermediada pelo sistema imunogênico, transmitida por carrapatos (especialmente do Gênero Ixodes) e causada por uma espiroqueta recentemente descoberta, a Borrelia burgdorferi. A técnica de Imunofluorescência Indireta (IF) é com freqüência usada para confirmar o diagnóstico da infecção por este microrganismo. Embora os métodos práticos tenham limitações, é no entanto o único método prático para seu diagnóstico. Devido a não existência de registros prévios dessa doença na Argentina, foi realizada pesquisa seroepidemiológica para determinar a presença de imunoglobulinas nos trabalhadores rurais da Argentina, com sintomas de artrite. Sobre um total de 28 soros analisados, 3 resultaram positivos (o soro número 1 com um título de 1:320 para IgG, embora os soros números 5 e 9 ambos foram reativos a diluição 1:160). Esses mesmos soros foram analisados para a IgM sendo todos eles levemente reativos (1:40), usando IF. Os resultados mostram que anticorpos anti Borrelia burgdorferi se encontram presentes na população da Argentina. Deve-se ter, portanto, precaução na interpretação clínica das artrites até que a presença de Borrelia burgdorferi seja confirmada pelo cultivo nos meios específicos. Universidade de São Paulo. Faculdade de Saúde Pública1993-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/2398010.1590/S0034-89101993000400011Revista de Saúde Pública; Vol. 27 No. 4 (1993); 305-307 Revista de Saúde Pública; Vol. 27 Núm. 4 (1993); 305-307 Revista de Saúde Pública; v. 27 n. 4 (1993); 305-307 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/rsp/article/view/23980/25945Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessStanchi, Nestor OscarBalague, Laura Josefina2012-05-29T16:13:30Zoai:revistas.usp.br:article/23980Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-05-29T16:13:30Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
Doença de Lyme: anticorpos anti Borrelia burgdorferi nos trabalhadores rurais da Argentina
title Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
spellingShingle Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
Stanchi, Nestor Oscar
Doença de Lyme^i2^sdiagnóst
Borrelia Burgdorferi^i2^simunolo
Trabalhadores rurais
Anticorpos anti-bactérias
Lyme disease^i1^sdiagnos
Borrelia burgdorferi^i1^simunol
Rural workers
Antibodies^i1^sbacter
title_short Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
title_full Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
title_fullStr Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
title_full_unstemmed Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
title_sort Lyme Disease: antibodies against Borrelia burgdorferi in farm workers in Argentina
author Stanchi, Nestor Oscar
author_facet Stanchi, Nestor Oscar
Balague, Laura Josefina
author_role author
author2 Balague, Laura Josefina
author2_role author
dc.contributor.author.fl_str_mv Stanchi, Nestor Oscar
Balague, Laura Josefina
dc.subject.por.fl_str_mv Doença de Lyme^i2^sdiagnóst
Borrelia Burgdorferi^i2^simunolo
Trabalhadores rurais
Anticorpos anti-bactérias
Lyme disease^i1^sdiagnos
Borrelia burgdorferi^i1^simunol
Rural workers
Antibodies^i1^sbacter
topic Doença de Lyme^i2^sdiagnóst
Borrelia Burgdorferi^i2^simunolo
Trabalhadores rurais
Anticorpos anti-bactérias
Lyme disease^i1^sdiagnos
Borrelia burgdorferi^i1^simunol
Rural workers
Antibodies^i1^sbacter
description Lyme Disease is a tick-borne (specially by Ixodes ticks) immune-mediated inflammatory disorder caused by a newly recognize spirochete, Borrelia burgdorferi. Indirect fluorescent antibody (IF) staining methods and enzyme-linked immunosorbent assay are frequently relied upon to confirm Lyme borreliosis infections. Although serologic testing for antibodies has limitations, it is still the only practical means of confirming B. burgdorferi infections. Because we have no previous report of Lyme disease in human inhabitants in Argentina, a study was designed as a seroepidemiologic investigation of the immune response to B. burgdorferi in farm workers of Argentina with arthritis symptoms. Three out of 28 sera were positive (#1,5 and 9). Serum # 1 was positive for Immunoglobulin G at dilution 1:320, serum # 5 and # 9 both to dilution 1:160; while for Immunoglobulin M all (#1, 5 and 9) were positive at low dilution (1:40) using IF. The results showed that antibodies against B. burgdorferi are present in an Argentinian population. Thus caution should be exercised in the clinical interpretation of arthritis until the presence of B. burgdorferi be confirmed by culture in specific media.
publishDate 1993
dc.date.none.fl_str_mv 1993-08-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/23980
10.1590/S0034-89101993000400011
url https://www.revistas.usp.br/rsp/article/view/23980
identifier_str_mv 10.1590/S0034-89101993000400011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/23980/25945
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 27 No. 4 (1993); 305-307
Revista de Saúde Pública; Vol. 27 Núm. 4 (1993); 305-307
Revista de Saúde Pública; v. 27 n. 4 (1993); 305-307
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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