Effectiveness Of 2% And 4% Papain Gels In The Healing Of Venous Ulcers

• Autor(a) principal: Ribeiro,Andréa Pinto Leite
• Data de Publicação: 2015
• Outros Autores: Oliveira,Beatriz Guitton Renaud Baptista de, Soares,Marja Ferreira, Barreto,Bruna Maiara Ferreira, Futuro,Débora Omena, Castilho,Selma Rodrigues de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Escola de Enfermagem da USP (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342015000300394
• topic: Varicose Ulcer; Leg Ulcer; Papain; Treatment Outcome; Nursing

OBJECTIVE To analyze the effectiveness of 2% and 4% papain gels in tissue repair of venous ulcers. METHOD Quasi-experimental study with consecutive sample of 16 patients with 30 venous ulcers treated at the outpatient clinic of a teaching hospital, from April to November in 2011, using a form for clinical assessment of the patient and its lesion. Variables were analyzed by Wilcoxon and McNemar test (p < 0.05). RESULTS Most participants were female; aged between 51 and 59 years; obese; with hypertension. Regarding ulcers, there was an average decrease of 7.9 cm2 (50% of its original size) in 90 days; 20% of the ulcers completely healed within 56.67 days. There was an increase in epithelialization, significant reduction in the slough and edema, improved depth, in the type and amount of exudate (p < 0.0001). CONCLUSION 2% and 4% papain gels were effective in healing venous ulcers.