Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs

Detalhes bibliográficos
Autor(a) principal: Mattos, Leda Ulson
Data de Publicação: 1975
Outros Autores: Salum, Mana Josefina Leuba, Amaral, Maria Leonor Correa Pimentel
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista da Escola de Enfermagem da USP (Online)
Texto Completo: https://www.revistas.usp.br/reeusp/article/view/135417
Resumo: In order to study protein-calorie malnutrition two experimental models-calorie deficient and protein deficient models-have been produced in young female rats. When the mean weight of the rats of both models were 48g, the animals were killed. The spleen, liver, kidney, heart and pancreas were studied in relation to weight and nitrogen content, and compared to a control group of the same body weight. In the calorie deficient model only the spleen lost weight, but apparently its composition was unchanged. In the protein deficient model the weight of the liver and pancreas remained similar to those of the control group, but their composition was modified: both organs lost nitiogen and the liver accumulated fat.
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spelling Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organsESTUDO PONDERAL E BIOQUÍMICO DE ALGUNS ÓRGÃOS DE RATAS SUBMETIDAS À DESNUTRIÇÃO PROTÉICA OU CALÓRICA, APÓS O DESMAMEIn order to study protein-calorie malnutrition two experimental models-calorie deficient and protein deficient models-have been produced in young female rats. When the mean weight of the rats of both models were 48g, the animals were killed. The spleen, liver, kidney, heart and pancreas were studied in relation to weight and nitrogen content, and compared to a control group of the same body weight. In the calorie deficient model only the spleen lost weight, but apparently its composition was unchanged. In the protein deficient model the weight of the liver and pancreas remained similar to those of the control group, but their composition was modified: both organs lost nitiogen and the liver accumulated fat.Os autores fizeram um estudo ponderal e bioquímico do fígado, baço, rim, coração e páncreas de ratas pertencentes a três grupos, com peso médio de 48 g, e que haviam sido alimentadas com três modelos experimentais de dietas, balanceada, deficiente em proteínas ou em calorias --, até atingirem o referido peso médio. Os animais dos modelos hipoprotéico e hipocalórico ao atingirem o peso pré-estabelecido tinham 47 dias de idade e os da dieta balanceada 26 dias. Verificaram que as maiores alterações no peso e no comportamento bioquímico dos órgãos ocorreram no fígado e páncreas dos animais com dieta hipoprotéico. Os órgãos dos animais que haviam sofrido restrição calórica não apresentaram diferenças significativas em relação aos dos animais considerados normais, com exceção do baço que. embora aparentemente não tivesse sua composição alterada, perdeu peso.Universidade de São Paulo. Escola de Enfermagem1975-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/reeusp/article/view/13541710.1590/0080-6234197500900100035Revista da Escola de Enfermagem da USP; v. 9 n. 1 (1975); 35-47Revista da Escola de Enfermagem da USP; Vol. 9 No. 1 (1975); 35-47Revista da Escola de Enfermagem da USP; Vol. 9 Núm. 1 (1975); 35-471980-220X0080-6234reponame:Revista da Escola de Enfermagem da USP (Online)instname:Universidade de São Paulo (USP)instacron:USPporhttps://www.revistas.usp.br/reeusp/article/view/135417/131269http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessMattos, Leda UlsonSalum, Mana Josefina LeubaAmaral, Maria Leonor Correa Pimentel2017-08-11T19:20:22Zoai:revistas.usp.br:article/135417Revistahttps://www.revistas.usp.br/reeuspPUBhttps://www.revistas.usp.br/reeusp/oai||nursingscholar@usp.br1980-220X0080-6234opendoar:2017-08-11T19:20:22Revista da Escola de Enfermagem da USP (Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
ESTUDO PONDERAL E BIOQUÍMICO DE ALGUNS ÓRGÃOS DE RATAS SUBMETIDAS À DESNUTRIÇÃO PROTÉICA OU CALÓRICA, APÓS O DESMAME
title Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
spellingShingle Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
Mattos, Leda Ulson
title_short Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
title_full Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
title_fullStr Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
title_full_unstemmed Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
title_sort Experimental protein-calorie malnutrition induced in early weaned female rats-Weight and biochemistry studies of some organs
author Mattos, Leda Ulson
author_facet Mattos, Leda Ulson
Salum, Mana Josefina Leuba
Amaral, Maria Leonor Correa Pimentel
author_role author
author2 Salum, Mana Josefina Leuba
Amaral, Maria Leonor Correa Pimentel
author2_role author
author
dc.contributor.author.fl_str_mv Mattos, Leda Ulson
Salum, Mana Josefina Leuba
Amaral, Maria Leonor Correa Pimentel
description In order to study protein-calorie malnutrition two experimental models-calorie deficient and protein deficient models-have been produced in young female rats. When the mean weight of the rats of both models were 48g, the animals were killed. The spleen, liver, kidney, heart and pancreas were studied in relation to weight and nitrogen content, and compared to a control group of the same body weight. In the calorie deficient model only the spleen lost weight, but apparently its composition was unchanged. In the protein deficient model the weight of the liver and pancreas remained similar to those of the control group, but their composition was modified: both organs lost nitiogen and the liver accumulated fat.
publishDate 1975
dc.date.none.fl_str_mv 1975-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/reeusp/article/view/135417
10.1590/0080-6234197500900100035
url https://www.revistas.usp.br/reeusp/article/view/135417
identifier_str_mv 10.1590/0080-6234197500900100035
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/reeusp/article/view/135417/131269
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Escola de Enfermagem
publisher.none.fl_str_mv Universidade de São Paulo. Escola de Enfermagem
dc.source.none.fl_str_mv Revista da Escola de Enfermagem da USP; v. 9 n. 1 (1975); 35-47
Revista da Escola de Enfermagem da USP; Vol. 9 No. 1 (1975); 35-47
Revista da Escola de Enfermagem da USP; Vol. 9 Núm. 1 (1975); 35-47
1980-220X
0080-6234
reponame:Revista da Escola de Enfermagem da USP (Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista da Escola de Enfermagem da USP (Online)
collection Revista da Escola de Enfermagem da USP (Online)
repository.name.fl_str_mv Revista da Escola de Enfermagem da USP (Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ||nursingscholar@usp.br
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