Contrast-induced acute kidney injury in patients submitted to coronary angioplasty: prospective cohort

• Autor(a) principal: Moitinho,Matheus Santos
• Data de Publicação: 2022
• Outros Autores: Silva Junior,Jumar Reis Da, Cunha,Maximina De Barros, Barbosa,Dulce Aparecida, Caixeta,Adriano Mendes, Pimpinato,Attilio Galhardo, Junglos,Alana Francine, Belasco,Angélica Gonçalves Da Silva, Fonseca,Cassiane Dezoti da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Revista da Escola de Enfermagem da USP (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0080-62342022000200406
• topic: Kidney Diseases; Acute Kidney Injury; Contrast Media; Percutaneous Coronary Intervention; Acute Coronary Syndrome

ABSTRACT Objective: To analyze the incidence, risk factors, and associations of clinical outcomes for contrast-induced acute kidney injury (CI-AKI) in patients with acute coronary syndrome (ACS) after coronary angioplasty. Method: Prospective cohort of 182 patients followed for three months after undergoing angioplasty, from July 2020 to June 2021. The analyzed variables were sociodemographic, clinical, and those related to the procedure. Results: The incidence of CI-AKI was 35.7% (n = 65) and was associated with old age, diabetes mellitus, and chronic kidney disease (p = 0.004, p < 0.001, and p = 0.009, respectively). Out of the 17 patients who died within 90 days, 76.5% had CI-AKI (n = 13), the odds ratio between death and CI-AKI was approximately 7.2 times (95% confidence interval (CI), [2.41;26.36]; p = 0.001). The decrease of one unit in the patient’s baseline hemoglobin showed a 6.5% increase for CI-AKI (95% CI, [−0.089; −0.040]; p < 0.0001). Conclusion: CI-AKI is prevalent in patients with ACS after angioplasty and is related to diabetes mellitus and chronic kidney disease, showing high mortality rates.