Alumina applied in bone regeneration: Porous α-alumina and transition alumina

Detalhes bibliográficos
Autor(a) principal: Silva,J. R. S.
Data de Publicação: 2022
Outros Autores: Santos,L. N. R. M., Farias,R. M. C., Sousa,B. V., Neves,G. A., Menezes,R. R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Cerâmica (São Paulo. Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132022000300355
Resumo: Abstract Alumina is a polymorphic bioceramic that has been extensively investigated for application in bone regeneration. Dense α-alumina has been considered a suitable biomaterial for dental and orthopedic implants due to its superior mechanical properties. However, its use is limited due to its high inertia in a biological environment. Recent investigations have focused on its distinct phases and surface characteristics through the control of morphology, physical properties, and chemical composition to enhance bioactivity. This article presents a brief review of the developments in porous α-alumina and amorphous-γ-alumina transition. Most studies have shown that composites and alumina coated with bioactive materials, high surface area, and hydroxylated surface can significantly improve biological properties. Cellular responses such as fixation, growth, and proliferation, as well as biomineralization, are the main studies to validate improvements in bioactive properties.
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spelling Alumina applied in bone regeneration: Porous α-alumina and transition aluminaporous α-aluminaalumina transitionbioactivitybone tissueAbstract Alumina is a polymorphic bioceramic that has been extensively investigated for application in bone regeneration. Dense α-alumina has been considered a suitable biomaterial for dental and orthopedic implants due to its superior mechanical properties. However, its use is limited due to its high inertia in a biological environment. Recent investigations have focused on its distinct phases and surface characteristics through the control of morphology, physical properties, and chemical composition to enhance bioactivity. This article presents a brief review of the developments in porous α-alumina and amorphous-γ-alumina transition. Most studies have shown that composites and alumina coated with bioactive materials, high surface area, and hydroxylated surface can significantly improve biological properties. Cellular responses such as fixation, growth, and proliferation, as well as biomineralization, are the main studies to validate improvements in bioactive properties.Associação Brasileira de Cerâmica2022-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132022000300355Cerâmica v.68 n.387 2022reponame:Cerâmica (São Paulo. Online)instname:Universidade de São Paulo (USP)instacron:USP10.1590/0366-69132022683873335info:eu-repo/semantics/openAccessSilva,J. R. S.Santos,L. N. R. M.Farias,R. M. C.Sousa,B. V.Neves,G. A.Menezes,R. R.eng2022-09-12T00:00:00Zoai:scielo:S0366-69132022000300355Revistahttps://www.scielo.br/j/ce/PUBhttps://old.scielo.br/oai/scielo-oai.phpceram.abc@gmail.com||ceram.abc@gmail.com1678-45530366-6913opendoar:2022-09-12T00:00Cerâmica (São Paulo. Online) - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Alumina applied in bone regeneration: Porous α-alumina and transition alumina
title Alumina applied in bone regeneration: Porous α-alumina and transition alumina
spellingShingle Alumina applied in bone regeneration: Porous α-alumina and transition alumina
Silva,J. R. S.
porous α-alumina
alumina transition
bioactivity
bone tissue
title_short Alumina applied in bone regeneration: Porous α-alumina and transition alumina
title_full Alumina applied in bone regeneration: Porous α-alumina and transition alumina
title_fullStr Alumina applied in bone regeneration: Porous α-alumina and transition alumina
title_full_unstemmed Alumina applied in bone regeneration: Porous α-alumina and transition alumina
title_sort Alumina applied in bone regeneration: Porous α-alumina and transition alumina
author Silva,J. R. S.
author_facet Silva,J. R. S.
Santos,L. N. R. M.
Farias,R. M. C.
Sousa,B. V.
Neves,G. A.
Menezes,R. R.
author_role author
author2 Santos,L. N. R. M.
Farias,R. M. C.
Sousa,B. V.
Neves,G. A.
Menezes,R. R.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Silva,J. R. S.
Santos,L. N. R. M.
Farias,R. M. C.
Sousa,B. V.
Neves,G. A.
Menezes,R. R.
dc.subject.por.fl_str_mv porous α-alumina
alumina transition
bioactivity
bone tissue
topic porous α-alumina
alumina transition
bioactivity
bone tissue
description Abstract Alumina is a polymorphic bioceramic that has been extensively investigated for application in bone regeneration. Dense α-alumina has been considered a suitable biomaterial for dental and orthopedic implants due to its superior mechanical properties. However, its use is limited due to its high inertia in a biological environment. Recent investigations have focused on its distinct phases and surface characteristics through the control of morphology, physical properties, and chemical composition to enhance bioactivity. This article presents a brief review of the developments in porous α-alumina and amorphous-γ-alumina transition. Most studies have shown that composites and alumina coated with bioactive materials, high surface area, and hydroxylated surface can significantly improve biological properties. Cellular responses such as fixation, growth, and proliferation, as well as biomineralization, are the main studies to validate improvements in bioactive properties.
publishDate 2022
dc.date.none.fl_str_mv 2022-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132022000300355
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0366-69132022000300355
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0366-69132022683873335
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Cerâmica
publisher.none.fl_str_mv Associação Brasileira de Cerâmica
dc.source.none.fl_str_mv Cerâmica v.68 n.387 2022
reponame:Cerâmica (São Paulo. Online)
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Cerâmica (São Paulo. Online)
collection Cerâmica (São Paulo. Online)
repository.name.fl_str_mv Cerâmica (São Paulo. Online) - Universidade de São Paulo (USP)
repository.mail.fl_str_mv ceram.abc@gmail.com||ceram.abc@gmail.com
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